Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Takashi Kakinuma"'
Publikováno v:
SAE Technical Paper Series.
Autor:
Shinichi Sato, Manabu Tomita, Hanako Ohmatsu, Yoshihide Asano, Yayoi Tada, Takafumi Kadono, Makoto Sugaya, Hiromichi Kai, Takashi Kakinuma
Publikováno v:
Pathology - Research and Practice. 207:43-48
C-C chemokine receptor (CCR)10 is a specific receptor for chemokine ligand (CCL)27, a selective chemoattractant for skin-associated memory T cells to cutaneous sites. In melanoma, CCR10 increases the ability of neoplastic cells to grow, invade tissue
Autor:
Takafumi Kadono, Tomomitsu Miyagaki, Shinichi Sato, Hideki Fujita, Hanako Ohmatsu, Takashi Kakinuma, Kunihiko Tamaki, Makoto Sugaya
Publikováno v:
Journal of Investigative Dermatology. 130(9):2304-2311
CC chemokine receptor 3 (CCR3), the sole receptor for eotaxins, is expressed on eosinophils and T helper type 2 (Th2) cells. In Hodgkin's disease, eotaxin-1 secreted by fibroblasts collects Th2 cells and eosinophils within the tissue. Similarly, many
Autor:
Waldemar L. Olszewski, Emily Cha, Hong Zhang, Marzanna Zaleska, Lei Fang, Vivian C. Lee, Anke S. Lonsdorf, Takashi Kakinuma, Victor Huang, Keisuke Nagao, Samuel T Hwang
Publikováno v:
The Journal of Immunology. 180:6462-6466
CC chemokine receptor 10 and its ligand, CCL27, are important components of T cell-mediated cutaneous immunity, but whether they influence lymph node (LN) homing by T cells is unknown. In this study, CCL27 protein was detected in skin-draining LN by
Autor:
Takashi Kakinuma, Yasmine Belkaid, Hari Nadiminti, Samuel T Hwang, Takashi Murakami, Bradford A. Perez, Anke S. Lonsdorf, Gulnar Pothiawala, Steven E. Finkelstein, Hisataka Kobayashi
Publikováno v:
Cancer Immunology, Immunotherapy. 56:1119-1131
Luciferase-transduced B16 murine melanoma cells (luc-B16) inoculated in ear skin do not form tumors but prevent tumor formation by luc-B16 cells injected into the footpad. To determine the requirements for such immunity, we followed the fate of luc-B
Autor:
Takashi Kakinuma, Samuel T Hwang
Publikováno v:
Journal of Leukocyte Biology. 79:639-651
It is clear from large clinical studies that selected chemokine receptors are often up-regulated in a large number of common human cancers, including those of the breast, lung, prostate, colon, and melanoma. Chemokine receptors and their correspondin
Autor:
Akihiko Asahina, Mayumi Komine, Shinji Kagami, Takashi Kakinuma, Koichiro Nakamura, Kunihiko Tamaki, Hidehisa Saeki, Kiyo Sasaki, Yuichiro Tsunemi
Publikováno v:
Experimental Dermatology. 15:95-100
Both CCL27 and CCL28 are ligands for CCR10 and attract CCR10(+) lymphocytes. We previously demonstrated that CCL27 and CCL28 were strongly expressed in sera and lesional keratinocytes of patients with atopic dermatitis and psoriasis vulgaris. However
Autor:
Mayumi Komine, Takashi Kakinuma, S. Kagami, Yasushi Hanakawa, Koji Hashimoto, Kunihiko Tamaki
Publikováno v:
Journal of Investigative Dermatology. 125:491-498
Stimulation with tumor necrosis factor (TNF)alpha and interferon (IFN)gamma synergistically induced thymus- and activation-regulated chemokine (TARC)/CCL17 production from HaCaT keratinocytes (KC). Inhibitors for nuclear factor kappa B (NFkappaB), pa
Autor:
S. Kagami, Akihiko Asahina, Kunihiko Tamaki, Mayumi Komine, Kiyo Sasaki, Hidehisa Saeki, Takashi Kakinuma, Yuichiro Tsunemi, Koichiro Nakamura
Publikováno v:
Clinical and Experimental Immunology. 141:459-466
SummaryEotaxin-2/CCL24 and eotaxin-3/CCL26 are CC chemokines and their receptor, CC chemokine receptor 3 is preferentially expressed on eosinophils. It was reported that vascular endothelial cells and dermal fibroblasts produced CCL26. However, the r
Autor:
Ken Ohta, Shinji Kagami, Takashi Kakinuma, Koichi Hirai, Yuichiro Tsunemi, Motoshi Wakugawa, Takashi Sekiya, Koichiro Nakamura, Noriko Asano, Hideki Fujita, Hideshi Torii, Kunihiko Tamaki, Hidehisa Saeki, Yuka Tanida
Publikováno v:
Acta Dermato-Venereologica. 84:187-190
CCR4, a member of the CC chemokine receptor family, is believed to play an important role in the pathogenesis of atopic dermatitis. To examine whether CCR4 single nucleotide polymorphism (SNP) is associated with susceptibility to atopic dermatitis, w