Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Takashi Kajima"'
Autor:
Hirofumi Kuroda, Huiming Zhang, Yuki Komatsu, Naoki Asakawa, Yongbo Hu, Akio Kayano, Takashi Hasebe, Takashi Kajima, Xiang Niu, Yorihisa Hoshino, Charles E. Chase, Francis G. Fang, Tomohiro Watanabe, Hiroyuki Ishizuka, Thomas Noland, Matthew J. Schnaderbeck, Thomas E. Horstmann, Naoki Asai, Mamoru Miyazawa, Katsuya Tagami, Brian Austad, Manabu Kubota, John D. Orr, Trevor Lee Calkins, Hiroyuki Chiba, Bryan M. Lewis
Publikováno v:
Synlett. 24:333-337
The evolution of the synthesis of Halaven® (E7389, INN eribulin mesylate) from a medicinal chemistry process to the execution of the final process on pilot scale is described. The completion of the synthesis of Halaven® from C1–C13 ester and C14
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 40:345-352
An on-line purification method for cationic compounds and their metabolites in rat bile was investigated using a column-switching technique. 8-Hydroxyquinoline and its glucuronide were used as test compounds. Bile samples were injected directly into
Publikováno v:
Journal of Pharmaceutical Sciences. 91:933-942
We developed a rapid screening method for determination of pKa of candidate drugs by pressure-assisted capillary electrophoresis (CE) coupled with a photodiode array detector. Application of pressure during CE analysis allowed completion of one CE ru
Publikováno v:
Journal of Chromatography A. 829:411-415
This is a report on a capillary electrophoretic approach for the quantitation of the counter ions of drugs that are insoluble or slightly soluble in water. Using a nonaqueous run buffer, the sample solvents were not restricted, which is not the case
Autor:
Teruaki Yuzuriha, Yutaka Yoshida, Tsuneo Wakabayashi, Hiroyasu Yamamoto, Takashi Kajima, Takashi Shigematsu, Kazuto Yamazaki, Yoshindo Kawaguchi
Publikováno v:
Journal of Bone and Mineral Metabolism. 13:87-92
Accumulation of aluminum (Al) in the brain and bone has been implicated in the development of encephalopathy and osteodystrophy in patients with renal failure, and it has been reported that citric acid enhances Al absorption and retention. Oral iron
Autor:
Takashi Kajima, Yoshihisa Kawamura
Publikováno v:
IEEJ Transactions on Industry Applications. 114:769-777
Development of a solenoid which was used for the high-speed solenoidvalve with a 1 ms switching time is discussed in this paper.First, by using the mathematical model, we quantitatively studied the effects of design particu lars, such as the dimensio
Publikováno v:
TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series C. 60:2744-2751
Publikováno v:
Pharmaceutical Research. :997-1001
An on-line simultaneous assay for the enantiomers of verapamil (VA) and its three metabolites in plasma was developed with column-switching HPLC. This system consists of an ovomucoid protein chiral stationary phase coupled to an achiral reversed-phas
Publikováno v:
Journal of Chromatography A. 541:411-418
High-performance liquid chromatography (HPLC) with column switching was applied to the on-line determination and resolution of the enantiomers of verapamil (VA). This system employs an achiral reversed-phase column coupled to a chiral ovomucoid colum
Autor:
Takashi Kajima
Publikováno v:
JOURNAL OF THE MARINE ENGINEERING SOCIETY IN JAPAN. 26:277-286