Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Takashi K. Ito"'
Autor:
Takashi K. Ito, Tomohito Sato, Yusuke Takanashi, Zinat Tamannaa, Takuya Kitamoto, Keiichi Odagiri, Mitsutoshi Setou
Publikováno v:
Translational Medicine of Aging, Vol 5, Iss , Pp 43-51 (2021)
A decrease in nicotinamide adenine dinucleotide (NAD+) levels is a hallmark of aging in multiple species, including humans. Our previous clinical trial showed that supplementation of 200 mg nicotinamide, a form of vitamin B3, increased blood NAD+ lev
Externí odkaz:
https://doaj.org/article/2049627f6360406f8f653386934dc2ab
Autor:
Takashi K. Ito, Tomohito Sato, Akio Hakamata, Yuki Onoda, Shumpei Sato, Fumiyoshi Yamazaki, Makoto Horikawa, Yutaka Takahashi, Takuya Kitamoto, Masako Suzuki, Shinya Uchida, Keiichi Odagiri, Mitsutoshi Setou
Publikováno v:
Translational Medicine of Aging, Vol 4, Iss , Pp 45-54 (2020)
A decrease in nicotinamide adenine dinucleotide (NAD+) levels is a hallmark of aging in multiple organisms, including humans. We report a human clinical trial designed to assess the efficacy of single-dose supplementation of nicotinamide, a form of v
Externí odkaz:
https://doaj.org/article/f4fdfd2190064feea97ad4bed3f1f17e
Autor:
Md. Al Mamun, Shumpei Sato, Eiji Naru, Osamu Sakata, Emi Hoshikawa, Ayako Suzuki, Ariful Islam, Tomoaki Kahyo, Tomohito Sato, Takashi K. Ito, Makoto Horikawa, Reimu Fukui, Kenji Izumi, Mitsutoshi Setou
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8, p 2807 (2020)
The vermilion of the human lip is a unique facial area because of certain distinguishing features from the adjacent tissues such as the white lip (skin) and oral mucosa. However, the distinction in terms of molecular distribution between the vermilio
Externí odkaz:
https://doaj.org/article/d0cd1f2024784e87a8a66a6e9b0509bc
Autor:
Emiko Takeyama, Ariful Islam, Nakamichi Watanabe, Hiroe Tsubaki, Masako Fukushima, Md. Al Mamun, Shumpei Sato, Tomohito Sato, Fumihiro Eto, Ikuko Yao, Takashi K. Ito, Makoto Horikawa, Mitsutoshi Setou
Publikováno v:
Nutrients, Vol 11, Iss 10, p 2371 (2019)
Docosahexaenoic acid (DHA), an omega-3 polyunsaturated fatty acid, has significant health benefits. Previous studies reported decreased levels of DHA and DHA-containing phosphatidylcholines in the brain of animals suffering from Alzheimer’s disease
Externí odkaz:
https://doaj.org/article/e72b8388e3ad43b0b68d62ce1ed64fd8
Autor:
Takashi K. Ito, Chenhao Lu, Jacob Khan, Quy Nguyen, Heather Z. Huang, Dayae Kim, James J. Phillips, Jo Tan, Yenna Lee, Tuyet Nguyen, Samy Khessib, Natalie Lim, Surapat Mekvanich, Joshua Oh, Victor V. Pineda, Weirong Wang, Alessandro Bitto, Jonathan Y. An, John F. Morton, Mitsutoshi Setou, Warren C. Ladiges, Matt Kaeberlein
Publikováno v:
Frontiers in Genetics, Vol 8 (2017)
Externí odkaz:
https://doaj.org/article/c99404f4c52046d6b736e90ad388d71e
Autor:
Takashi K. Ito, Chenhao Lu, Jacob Khan, Quy Nguyen, Heather Z. Huang, Dayae Kim, James Phillips, Jo Tan, Yenna Lee, Tuyet Nguyen, Samy Khessib, Natalie Lim, Surapat Mekvanich, Joshua Oh, Victor V. Pineda, Weirong Wang, Alessandro Bitto, Jonathan Y. An, John F. Morton, Mitsutoshi Setou, Warren C. Ladiges, Matt Kaeberlein
Publikováno v:
Frontiers in Genetics, Vol 8 (2017)
The inactivation of ribosomal protein S6 kinase 1 (S6K1) recapitulates aspects of caloric restriction and mTORC1 inhibition to achieve prolonged longevity in invertebrate and mouse models. In addition to delaying normative aging, inhibition of mTORC1
Externí odkaz:
https://doaj.org/article/b9e4abcd91a34deea0dfa54c43c48b29
Autor:
Kosuke Hashimoto, Soichiro Ide, Mayumi Arata, Akiko Nakata, Akihiro Ito, Takashi K. Ito, Norio Kudo, Bangzhong Lin, Kazuto Nunomura, Keiko Tsuganezawa, Minoru Yoshida, Yasuo Nagaoka, Takaaki Sumiyoshi
Publikováno v:
ACS Medicinal Chemistry Letters. 13:1077-1082
Inhibition of histone deacetylase 6 (HDAC6) in the brain is a highly attractive therapeutic target for the treatment of neurodegenerative diseases. The low blood-brain barrier permeability of most known HDAC6 inhibitors, however, prevents their appli
Autor:
Zinat Tamannaa, Mitsutoshi Setou, Keiichi Odagiri, Yusuke Takanashi, Takashi K. Ito, Tomohito Sato, Takuya Kitamoto
Publikováno v:
Translational Medicine of Aging, Vol 5, Iss, Pp 43-51 (2021)
A decrease in nicotinamide adenine dinucleotide (NAD+) levels is a hallmark of aging in multiple species, including humans. Our previous clinical trial showed that supplementation of 200 mg nicotinamide, a form of vitamin B3, increased blood NAD+ lev
Autor:
Takuya Kitamoto, Yuki Onoda, Akio Hakamata, Shumpei Sato, Tomohito Sato, Yutaka Takahashi, Fumiyoshi Yamazaki, Mitsutoshi Setou, Masako Suzuki, Shinya Uchida, Makoto Horikawa, Keiichi Odagiri, Takashi K. Ito
Publikováno v:
Translational Medicine of Aging, Vol 4, Iss, Pp 45-54 (2020)
A decrease in nicotinamide adenine dinucleotide (NAD+) levels is a hallmark of aging in multiple organisms, including humans. We report a human clinical trial designed to assess the efficacy of single-dose supplementation of nicotinamide, a form of v
Autor:
Ayako Suzuki, Kenji Izumi, Tomohito Sato, Reimu Fukui, Osamu Sakata, Tomoaki Kahyo, Shumpei Sato, Eiji Naru, Takashi K. Ito, Ariful Islam, Makoto Horikawa, Mitsutoshi Setou, Emi Hoshikawa, Md. Al Mamun
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 8
International Journal of Molecular Sciences, Vol 21, Iss 2807, p 2807 (2020)
Volume 21
Issue 8
International Journal of Molecular Sciences, Vol 21, Iss 2807, p 2807 (2020)
The vermilion of the human lip is a unique facial area because of certain distinguishing features from the adjacent tissues such as the white lip (skin) and oral mucosa. However, the distinction in terms of molecular distribution between the vermilio