Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Takashi Homan"'
Autor:
Takashi Homan, Tetsunori Tsuzuki, Koji Dogishi, Hisashi Shirakawa, Tatsuya Oyama, Takayuki Nakagawa, Shuji Kaneko
Publikováno v:
Journal of Pharmacological Sciences, Vol 121, Iss 4, Pp 327-337 (2013)
Abstract.: There is so far no generally accepted animal model of chronic cystitis by which potential therapies can be evaluated. In this study, we aimed to establish a new mouse model of cystitis based on the proinflammatory effects of reactive oxyge
Externí odkaz:
https://doaj.org/article/7924349959434522acb32772fe7c9fd2
Autor:
Naoki Yoshimura, Takayuki Nakagawa, Shohei Oyama, Ken Okamoto, Koji Dogishi, Tatsuya Oyama, Shizuka Konishi‐Shiotsu, Takashi Homan, Shuji Kaneko, Mizuki Kodera, Tsuyoshi Majima, Hisashi Shirakawa
Publikováno v:
Physiological Reports
Novel longer lasting inflammatory bladder animal models are needed to better understand the pathophysiology of chronic cystitis. We previously developed a relatively long‐lasting mouse cystitis model by intravesical injection of hydrogen peroxide (
Autor:
Tetsuya Asakawa, Takashi Homan, Atsu Todo, Yuko Mizuno-Matsumoto, Yasumasa Hitomi, Yoshihiro Tsuji, Masanori Yoshioka
Publikováno v:
Journal of the Japanese Society of Intensive Care Medicine. 21:24-28
Autor:
Hisashi Shirakawa, Tetsunori Tsuzuki, Tatsuya Oyama, Takayuki Nakagawa, Takashi Homan, Shuji Kaneko, Koji Dogishi
Publikováno v:
Journal of Pharmacological Sciences, Vol 121, Iss 4, Pp 327-337 (2013)
There is so far no generally accepted animal model of chronic cystitis by which potential therapies can be evaluated. In this study, we aimed to establish a new mouse model of cystitis based on the proinflammatory effects of reactive oxygen species.
Publikováno v:
European Journal of Pharmacology. 676:75-80
Tramadol is a widely used analgesic that stimulates the μ opioid receptor and inhibits serotonin and noradrenalin reuptake. There have been studies on the analgesic effects of tramadol based on the tail-flick test, the formalin test, and the inducti
Autor:
Yukihiko Sugimoto, Shuh Narumiya, Ken Ichiro Tanaka, Toshiharu Suzuki, Tatsuya Hoshino, Masami Narita, Takashi Homan, Tohru Mizushima, Tadashi Nakaya, Wataru Araki
Publikováno v:
Journal of Biological Chemistry. 282:32676-32688
Amyloid-beta peptides (Abeta), generated by proteolysis of the beta-amyloid precursor protein (APP) by beta- and gamma-secretases, play an important role in the pathogenesis of Alzheimer disease (AD). Inflammation is also believed to be integral to t
Publikováno v:
Neuroscience letters. 562
(±)-Tramadol hydrochloride (tramadol) is a widely used analgesic for the treatment of cancer pain and chronic pain. Although many animal studies have shown antinociceptive effects of tramadol in both acute and chronic pain, little is known about the
Autor:
Shinji Mima, Tohru Mizushima, Takashi Homan, Tomoko Nishimura, Takushi Namba, Tatsuya Hoshino
Publikováno v:
The Journal of biological chemistry. 284(7)
Epidemiological studies have revealed that prolonged use of non-steroidal anti-inflammatory drugs (NSAIDs) reduces the risk of cancer. Various mechanisms, including induction of apoptosis and inhibition of the growth and invasion of cancer cells, hav