Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Takashi Hironaka"'
Autor:
Brian Gazzard, Makoto Inoue, Etienne Karita, Angela Lombardo, Omu Anzala, Hiroto Hara, Julien Nyombayire, Takashi Hironaka, Gloria Omosa-Manyonyi, Jill Gilmour, Patricia E. Fast, Jean Bizimana, Tsugumine Shu, Josephine H. Cox, Akil Jackson, Peter Hayes, Christopher L. Parks, Philip Bergin, Bashir Farah, Eddy Sayeed, Burc Barin, Dagna Laufer, Tetsuro Matano, Jakub Kopycinski, Len Dally, Jean-Louis Excler, Harriet Park
Publikováno v:
The Journal of Infectious Diseases
Background. We report the first-in-human safety and immunogenicity assessment of a prototype intranasally administered, replication-competent Sendai virus (SeV)–vectored, human immunodeficiency virus type 1 (HIV-1) vaccine. Methods. Sixty-five HIV-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af5c1ce6ce30f2efd2da21275c631ee0
https://doi.org/10.1093/infdis/jiw500
https://doi.org/10.1093/infdis/jiw500
Autor:
Kamila M Pytel, Jean-François Gélinas, Deborah R. Gill, Lee A. Davies, Amit C. Nathwani, Stephen C. Hyde, Lidia Cammack, Makoto Inoue, Ian A. Pringle, Caroline Moran, Eric W.F.W. Alton, S Tsugumine, Michael C. Paul-Smith, Mario Chan, Takashi Hironaka, Loren Cameron, Cuixiang Meng, Uta Griesenbach, Jenny McIntosh, Robyn V. Bell
Publikováno v:
Gene Therapy
We have shown that a lentiviral vector (rSIV.F/HN) pseudotyped with the F and HN proteins from Sendai virus generates high levels of intracellular proteins after lung transduction. Here, we evaluate the use of rSIV.F/HN for production of secreted pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e3b640266d52e588db1236db1240c8
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Autor:
Hitoshi Iwasaki, Makoto Inoue, Hiroshi Ban, Mariko Yoshizaki, Mamoru Hasegawa, Yumiko Tokusumi, Takashi Hironaka, Akihiro Iida, Yoshiyuki Nagai
Publikováno v:
The Journal of Gene Medicine. 8:1151-1159
Background Sendai virus (SeV) is a new class of cytoplasmic RNA vector that is free from genotoxicity that infects and multiplies in most mammalian cells, and directs high-level transgene expression. We improved the vector by deleting all of the enve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c04831ac8f8585aa3e2cc40d9c49ff03
https://doi.org/10.1002/jgm.938
https://doi.org/10.1002/jgm.938
Autor:
Hou X, Takashi Hironaka, T Shiraki-Iida, Jie Zhu, Eric W.F.W. Alton, Uta Griesenbach, Duncan M. Geddes, T Shu, John A. Williams, Mamoru Hasegawa, Peter K. Jeffery, Stefano Ferrari
Publikováno v:
Gene Therapy. 11:1659-1664
Recombinant Sendai virus (SeV)-mediated gene transfer to differentiated airway epithelial cells has shown to be very efficient, because of its ability to overcome the intra- and extracellular barriers known to limit gene delivery. However, this virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd5f2e054e43de9fc34085f45a80ee81
https://doi.org/10.1038/sj.gt.3302334
https://doi.org/10.1038/sj.gt.3302334
Autor:
Mariko Yoshizaki, Takumi Kanaya, Takashi Hironaka, Hiroshi Ban, Makoto Inoue, Masayuki Shirakura, Yumiko Tokusumi, Mamoru Hasegawa, Akihiro Iida, Yoshiyuki Nagai
Publikováno v:
The Journal of Gene Medicine. 6:1069-1081
Background Sendai virus (SeV) is a new type of cytoplasmic RNA vector, which infects and replicates in most mammalian cells, directs high-level expression of the genes on its genome and is free from genotoxicity. In order to improve this vector, both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f7c932c6f82a806c86c40223ca070c
https://doi.org/10.1002/jgm.597
https://doi.org/10.1002/jgm.597
Autor:
Kanji Hirai, Toshiaki Oka, Hiroshi Azuma, Yoko Sakata, Takashi Hironaka, Akimasa Okuno, Toyoro Osato, Shosuke Imai, Kazuhiro Sasaki
Publikováno v:
Journal of Pediatric Hematology/Oncology. 18:387-391
Purpose: We described for the first time a patient with long-lasting, extremely high serum antibody titer against Epstein-Barr virus (EBV) viral capsid antigen and early antigen without clinical symptoms suggestive of active EBV infection; the patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8a7b570f30fbf1d89777806a0feff9
https://doi.org/10.1097/00043426-199611000-00011
https://doi.org/10.1097/00043426-199611000-00011
Autor:
Mamoru Hasegawa, Stephen C. Hyde, Johanna F. Dekkers, Takashi Hironaka, Stephanie G. Sumner-Jones, Kamila M Pytel, S Tsugumine, Marguerite W. Wasowicz, Tracy E. Higgins, Deborah R. Gill, A J Innes, Eric W.F.W. Alton, Ian A. Pringle, Makoto Inoue, Christopher Boyd, Lee A. Davies, Jane C. Davies, Jeffery M. Beekman, Uta Griesenbach
Publikováno v:
Molecular Therapy. 24:S214
Background: We have recently shown that non-viral gene therapy can stabilise the decline of lung function in cystic fibrosis (CF) patients. However, the effect was modest, and it is important to develop more potent gene transfer agents in parallel. F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8f02062ded14b9cb5a7362d22a3e633
https://doi.org/10.1016/s1525-0016(16)33343-3
https://doi.org/10.1016/s1525-0016(16)33343-3
Autor:
Yuzo Endo, A. Bernard, M. Ghoneim, Naoyuki Kitamura, Yasuhiro Amagasaki, Mian-Shin Tan, Lucia Spitali, Akira Inoue, Yau-Jiunn Lee, Tetsuya Mitarai, Peter Nilsson-Ehle, Seunghun Lee, Sun Ae Yoon, Masateru Tanegashima, Hiroyuki Shimatake, M.L.N.G. Malbrain, Fumihiko Hinoshita, M. Andújar, Ali Anarat, H.T. Heidemann, Sait Polat, G.L.Y. Lambrecht, D.J. Nikolic-Paterson, J. Gonzalez-Lorenzo, Hee Kyung Chun, Byung Kee Bang, Valery Waisbrut, Takao Kohsaka, Young Suk Yoon, Hiroko Yoshikawa, Mahito Nakayama, Ryuji Nagasawa, M. Mij, Naoki Maruyama, M.T. Medina-Cano, Shigeru Taketani, G. Virga, A. Cruz, Chul Woo Yang, Yoshiko Nakamura, G. Inselmann, Yosuke Ogura, Kimio Tomita, Shyi-Jang Shin, N.R. Robles, H. Verhaegen, Ilhan Tuncer, F. Fiorini, H. Hänel, Kanji Hirai, Teruaki Suzuki, M. Sobh, Takako Yamamoto, Atsushi Ono, H.Y. Lan, Takashi Hironaka, R.C. Atkins, Kazuo Isoda, Akira Hasegawa, Yasuhiro Nishimura, S. Hamed, V. Savić, Yoon Sik Chang, E. Siles, Yong Soo Kim, G. Amici, Yong Bok Koh, Seong S. Moon, Marcellino Corvinelli, Shiu-Ru Lin, Camillo Del Vecchio Blanco, V. Stefanović, Masayasu Inoue, J. Aneiros, Massimo Cirillo, Sonoo Mizuiri, Omasu Matsumura, Misa Sasai-Takedatsu, Raisa Kushnier, R. Čukuranović, Yohnosuke Kobayashi, M. Gómez-Morales, Sten-Erik Bäck, Ki Bae Seung, F. Moustafa, P.G. Kerr, W. Kottny, S. Bertolini, P. Hotz, Takatsugu Kojima, Lazaro Gotloib, Shozo Ishikawa, Kyu Bo Choi, Hiromichi Hemmi, P. Masturzo, C. Ramírez, P. Coremans, Yutaka Nakajima, Takehiro Ohara, Gülfiliz Gönlüşen, Yung-Hsiung Lai, Avshalom Shostak, L. Verbist, D. Aguilar, Yong Seok Oh, G.H. Tesch, A. Montes, R. Lauwerys, Juei-Hsiung Tsai, Masahiko Yamamoto, Tatsuo Fushimi, A. Blöhmer, Pietro Anastasio, R. García del Moral, Aytül Noyan, U. Nellessen, Tatsuo Sato, C. Gomez-Ainsua, Natale G. DeSanto, G. Trujillano, Jan Kurkus, Carmela Loguercio, D. Dojčinov, Masaaki Ishigami, M. Bustos, F. O’Valle, Akio Nakamura
Publikováno v:
Nephron. 70:I-VII
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfede1684023f66991a628c91165b1a3
https://doi.org/10.1159/000188633
https://doi.org/10.1159/000188633
Autor:
Toshiaki Oka, Yukio Sakiyama, Takashi Hironaka, Tsutomu Oh-ishi, Takashi Nakano, Hideaki Kikuta, Tetsurou Nagashima, Kanji Hirai, Shuzo Matsumoto
Publikováno v:
Blood. 82:3259-3264
A virus-associated hemophagocytic syndrome is characterized by high fever, liver dysfunction, coagulation abnormalities, pancytopenia, and a benign histiocytic proliferation with prominent hemophagocytosis in bone marrow, lymph node, spleen, and live
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a6e59b5840bd464c5c9afdef228631
https://doi.org/10.1182/blood.v82.11.3259.bloodjournal82113259
https://doi.org/10.1182/blood.v82.11.3259.bloodjournal82113259
Publikováno v:
Journal of Virological Methods. 44:141-154
We report a simple procedure for the detection of Epstein-Barr virus (EBV) by in situ DNA-RNA hybridization with an alkaline phosphatase-linked oligonucleotide probe. EBV-producing cell lines P3HR-1 and Akata were treated with phorbol ester and n-but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea61d7b7e2b565341c44c4c64d7c515c
https://doi.org/10.1016/0166-0934(93)90050-2
https://doi.org/10.1016/0166-0934(93)90050-2