Zobrazeno 1 - 10
of 1 172
pro vyhledávání: '"Takashi Shimizu"'
Autor:
Takemasa Nakamura, Takashi Shimizu, Naho Nishinakama, Reika Takahashi, Kohei Arasaki, Akihiko Uda, Kenta Watanabe, Masahisa Watarai
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Francisella tularensis, the causative agent of tularemia, is a facultative intracellular bacterium. Although the life cycle of this bacterium inside phagocytic cells (e.g., macrophages, neutrophils) has been well analyzed, the dif
Externí odkaz:
https://doaj.org/article/083329645f4d420786f1afc280220473
Publikováno v:
BMC Sports Science, Medicine and Rehabilitation, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Although recent studies have investigated the effects of flywheel (FW) training on muscle function, the effects of transient FW exercise on jump performance in athletes are unknown. This study examined the effects of single and re
Externí odkaz:
https://doaj.org/article/936d1114c0484645a02fe174a4b1653a
Publikováno v:
European Journal of Entomology, Vol 121, Iss 1, Pp 7-18 (2024)
The degeneration in flight ability in beetles has rarely been studied in detail with regard to the polymorphism of flight traits within species. However, intraspecific diversity in flight traits means that the flight ability of species is in the proc
Externí odkaz:
https://doaj.org/article/2fc36c958d15488c8765c15fb765cc8d
Publikováno v:
PLoS ONE, Vol 19, Iss 9, p e0310120 (2024)
Francisella tularensis is a causative agent of the zoonotic disease tularemia, and is highly pathogenic to humans. The pathogenicity of this bacterium is largely attributed to intracellular growth in host cells. Although several bacterial factors imp
Externí odkaz:
https://doaj.org/article/287fce3324fe4b899a518f3d9dabc5cc
Autor:
Takashi Shimizu, Eisuke Inoue, Ryotaro Ohkuma, Shinichi Kobayashi, Takuya Tsunoda, Satoshi Wada
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/1afbfe292d48439c963acc6084437cfe
Autor:
Takashi Shimizu, Eisuke Inoue, Ryotaro Ohkuma, Shinichi Kobayashi, Takuya Tsunoda, Satoshi Wada
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionCurrently, first-line immune checkpoint inhibitors (ICIs), including programmed cell death protein-1 (PD-1) inhibitors, are utilized as monotherapy in advanced non-small cell lung cancer (NSCLC) patients with high programmed death ligand-
Externí odkaz:
https://doaj.org/article/79df360ee61b4247bc78ebaffe4da883
Autor:
Ryotaro Ohkuma, Sakiko Miura, Satoshi Muto, Yoshitaka Toyomasu, Yuki Fujimoto, Katsuaki Ieguchi, Nobuyuki Onishi, Takashi Shimizu, Makoto Watanabe, Daisuke Takayanagi, Tsubasa Goshima, Atsushi Horiike, Kazuyuki Hamada, Hirotsugu Ariizumi, Masahiro Shimokawa, Yuya Hirasawa, Tomoyuki Ishiguro, Risako Suzuki, Nana Iriguchi, Toshiaki Tsurui, Emiko Mura, Sachiko Takenoshita, Kazuki Numajiri, Naoyuki Okabe, Kiyoshi Yoshimura, Mayumi Tsuji, Yuji Kiuchi, Toshiki Yajima, Hideyuki Ishida, Hiroyuki Suzuki, Toshiko Yamochi, Shinichi Kobayashi, Takuya Tsunoda, Satoshi Wada
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionProgrammed cell death ligand 1 (PD-L1) expression in tumor tissues is measured as a predictor of the therapeutic efficacy of immune checkpoint inhibitors (ICIs) in many cancer types. PD-L1 expression is evaluated by immunohistochemical st
Externí odkaz:
https://doaj.org/article/ae7a3794a1b04272bd831501907f335c
Autor:
Kensuke Shibata, Chihiro Motozono, Masamichi Nagae, Takashi Shimizu, Eri Ishikawa, Daisuke Motooka, Daisuke Okuzaki, Yoshihiro Izumi, Masatomo Takahashi, Nao Fujimori, James B. Wing, Takahide Hayano, Yoshiyuki Asai, Takeshi Bamba, Yoshihiro Ogawa, Makoto Furutani-Seiki, Mutsunori Shirai, Sho Yamasaki
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
MR1 functions as an antigen presenting protein on cells in addition to MAIT cells. Here the authors use an early T cell-specific Bcl11b-deficient mouse that develops autoimmunity through a population of nonconventional MR1-restricted T cells and char
Externí odkaz:
https://doaj.org/article/1ce0fcb8575d4b299f6edbd60a8b61b6
Autor:
Takashi Shimizu
As the world's third-ranking economic power, Japan's style of management, such as the lifetime employment system, the seniority system, and an enterprise union, has been well studied. However, little else is known about the Japanese management contro
Autor:
Hanako Hagio, Wataru Koyama, Shiori Hosaka, Aysenur Deniz Song, Janchiv Narantsatsral, Koji Matsuda, Tomohiro Sugihara, Takashi Shimizu, Mitsumasa Koyanagi, Akihisa Terakita, Masahiko Hibi
Publikováno v:
eLife, Vol 12 (2023)
G-protein-coupled receptors (GPCRs) transmit signals into cells depending on the G protein type. To analyze the functions of GPCR signaling, we assessed the effectiveness of animal G-protein-coupled bistable rhodopsins that can be controlled into act
Externí odkaz:
https://doaj.org/article/a4d2f0bc6e104590a7e2dd56d30dbabe