Zobrazeno 1 - 10
of 409
pro vyhledávání: '"Takashi, Yamamura"'
Autor:
Takashi Yamamura, Noriko Isobe, Izumi Kawachi, Chiyoko Nohara, Yusei Miyazaki, Minami Tomita, Takahiko Tsumuraya, Katsuhisa Yamashita, Jin Nakahara, Ichiro Nakashima, Kazuo Fujihara
Publikováno v:
Neurology and Therapy, Vol 13, Iss 5, Pp 1361-1383 (2024)
Abstract Introduction Satralizumab, an anti-interleukin-6 receptor antibody, is approved in Japan for relapse prevention in neuromyelitis optica spectrum disorder (NMOSD) and is undergoing post-marketing surveillance (PMS) of clinical use. We aimed t
Externí odkaz:
https://doaj.org/article/cacd9763b99f4053953f8a9a3963e85e
Autor:
Misako Minote, Wakiro Sato, Kimitoshi Kimura, Atsuko Kimura, Youwei Lin, Tomoko Okamoto, Ryosuke Takahashi, Takashi Yamamura
Publikováno v:
Immunological Medicine, Vol 47, Iss 3, Pp 151-165 (2024)
‘No evidence of disease activity (NEDA)’, judged by clinical and radiological findings, is a therapeutic goal in patients with multiple sclerosis (MS). It is, however, unclear if distinct biological mechanisms contribute to the maintenance of NED
Externí odkaz:
https://doaj.org/article/2818c12adf8f4488bdfb5691502b7be2
Autor:
Qingqi Lin, Yair Dorsett, Ali Mirza, Helen Tremlett, Laura Piccio, Erin E. Longbrake, Siobhan Ni Choileain, David A. Hafler, Laura M. Cox, Howard L. Weiner, Takashi Yamamura, Kun Chen, Yufeng Wu, Yanjiao Zhou
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Previous studies have identified a diverse group of microbial taxa that differ between patients with multiple sclerosis (MS) and the healthy population. However, interpreting findings on MS-associated microbiota is challenging, as
Externí odkaz:
https://doaj.org/article/fdb2ecafbcc14cf782be9fc55e5cfd28
Autor:
Yuji Takahashi, Noriko Sato, Wakiro Sato, Reiko Saika, Motohiro Okumura, Kazumasa Sekiguchi, Tomoko Okamoto, Hiroyuki Maki, Takashi Yamamura
Publikováno v:
BMJ Neurology Open, Vol 6, Iss 1 (2024)
Introduction Recently, there have been a few reports of atypical post-coronavirus disease 2019 (COVID-19) myelopathy manifesting tract-specific lesions similar to those due to vitamin B12 deficiency. However, the precise characteristics of imaging or
Externí odkaz:
https://doaj.org/article/a98466b5f7684aa4867381f70e2c1c14
Publikováno v:
The Journal of Reproduction and Development, Vol 69, Iss 4, Pp 218-222 (2023)
Secretion of pulsatile gonadotropin-releasing hormone (GnRH) is essential for reproduction. Kisspeptin neurons in the arcuate nucleus (ARC), which coexpress neurokinin B (NKB) and its receptor (NK3R), are believed to be components of the GnRH pulse g
Externí odkaz:
https://doaj.org/article/61597db9a9434bb09ab57c130e7fc651
Autor:
Simon Faissner, Marielena Bongert, Paulina Trendelenburg, Sandra Thiel, Takashi Yamamura, Kerstin Hellwig, Ralf Gold
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Background: Pregnancy in patients with multiple sclerosis (MS) is accompanied by a decline of relapse activity with increased risk of relapses 3 months post-partum, for unknown reasons. Eomesodermin + T-helper cells (Eomes + Th cells) are known to me
Externí odkaz:
https://doaj.org/article/def04d32359b4f41adfa56938d6d416f
Autor:
Tomoko Okamoto, Takami Ishizuka, Reiko Shimizu, Yasuko Asahina, Harumasa Nakamura, Yuko Shimizu, Yoichiro Nishida, Takanori Yokota, Youwei Lin, Wakiro Sato, Takashi Yamamura
Publikováno v:
JMIR Research Protocols, Vol 13, p e46709 (2024)
BackgroundMultiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system that causes myelin sheath damage and axonal degeneration. The glycolipid (2S, 3S, 4R)-1-O-(α-d-galactosyl)-2-tetracosanoylamino-1,3,4-nonaetriol (O
Externí odkaz:
https://doaj.org/article/a052a7e6077a44dea89f381c7681eb88
Autor:
Ben JE Raveney, Yosif El‐Darawish, Wakiro Sato, Yoshiyuki Arinuma, Kunihiro Yamaoka, Shohei Hori, Takashi Yamamura, Shinji Oki
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 10, Pp 1-20 (2022)
Abstract Pathogenic T helper cells (Th cells) that respond to self‐antigen cannot be easily distinguished from beneficial Th cells. These cells can generate systemic autoimmune disease in response to widely expressed self‐antigens. In this study,
Externí odkaz:
https://doaj.org/article/908a364dfebf4087845d57b4c24a7770
Autor:
Wakiro Sato, Daisuke Noto, Manabu Araki, Tomoko Okamoto, Youwei Lin, Hiromi Yamaguchi, Ryoko Kadowaki-Saga, Atsuko Kimura, Yukio Kimura, Noriko Sato, Takami Ishizuka, Harumasa Nakamura, Sachiko Miyake, Takashi Yamamura
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 16 (2023)
Background: Multiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system that causes the damage to the myelin sheath as well as axonal degeneration. Individuals with MS appear to have changes in the numbers and function
Externí odkaz:
https://doaj.org/article/2ec57a84f74c469d8c2030fb36813dfd
Autor:
Junichiro Takahashi, Tomoko Okamoto, Youwei Lin, Reiko Saika, Atsuko Katsumoto, Wakiro Sato, Takashi Yamamura, Yuji Takahashi
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundIndividuals with multiple sclerosis (MS) are vulnerable to all types of infection, because MS itself involves immunodeficiency, in addition to involving treatment with immunosuppressants. Simple predictive variables for infection that are e
Externí odkaz:
https://doaj.org/article/b058f1beba7e4c198d06d36223b86ee4