Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Takashi, Toyama"'
Autor:
Xi Zheng, Takashi Toyama, Stephanie Siu, Takayuki Kaneko, Hikari Sugiura, Shota Yamashita, Yoshiteru Shimoda, Masayuki Kanamori, Kotoko Arisawa, Hidenori Endo, Yoshiro Saito
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Glioblastoma (GBM) is one of the most aggressive and deadly brain tumors; however, its current therapeutic strategies are limited. Selenoprotein P (SeP; SELENOP, encoded by the SELENOP gene) is a unique selenium-containing protein that exhib
Externí odkaz:
https://doaj.org/article/c3b2bf493f134c6dbae7e02d1fbf1497
Autor:
Xinying Ye, Takashi Toyama, Keiko Taguchi, Kotoko Arisawa, Takayuki Kaneko, Ryouhei Tsutsumi, Masayuki Yamamoto, Yoshiro Saito
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-9 (2023)
Abstract Selenoprotein P (SeP) is a major selenoprotein in serum predominantly produced in the liver. Excess SeP impairs insulin secretion from the pancreas and insulin sensitivity in skeletal muscle, thus inhibition of SeP could be a therapeutic str
Externí odkaz:
https://doaj.org/article/038aa5dfb13447abb55a8e8f2603a42f
Autor:
Kentaro Matsumoto, Shenwei Ni, Hiroyuki Arai, Takashi Toyama, Yoshiro Saito, Takehiro Suzuki, Naoshi Dohmae, Kojiro Mukai, Tomohiko Taguchi
Publikováno v:
Cell Structure and Function, Vol 48, Iss 1, Pp 59-70 (2022)
Stimulator of interferon genes (STING) is an ER-localized transmembrane protein and the receptor for 2',3'-cyclic guanosine monophosphate–adenosine monophosphate (cGAMP), which is a second messenger produced by cGAMP synthase (cGAS), a cytosolic do
Externí odkaz:
https://doaj.org/article/107fff2f745949abad01f44bf228cfb1
Autor:
Takashi Toyama, Takayuki Hoshi, Takuya Noguchi, Yoshiro Saito, Atsushi Matsuzawa, Akira Naganuma, Gi-Wook Hwang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract We recently found that tumor necrosis factor-α (TNF-α) may be involved in neuronal cell death induced by methylmercury in the mouse brain. Here, we examined the cells involved in the induction of TNF-α expression by methylmercury in the m
Externí odkaz:
https://doaj.org/article/aca787f298bc4591813bd5c3c424b4f7
Autor:
Takuya Noguchi, Yuto Sekiguchi, Yuki Kudoh, Rio Naganuma, Tomohiro Kagi, Akiko Nishidate, Kazuhiro Maeda, Chizuru Ishii, Takashi Toyama, Yusuke Hirata, Gi-Wook Hwang, Atsushi Matsuzawa
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-17 (2021)
Abstract Anticancer drug gefitinib causes inflammation-based side effects, such as interstitial pneumonitis. However, its mechanisms remain unknown. Here, we provide evidence that gefitinib elicits pro-inflammatory responses by promoting mature-inter
Externí odkaz:
https://doaj.org/article/8caaaf62bd0b45138093e5fa58c4ec7a
Autor:
Kentaro Matsumoto, Shenwei Ni, Hiroyuki Arai, Takashi Toyama, Yoshiro Saito, Takehiro Suzuki, Naoshi Dohmae, Kojiro Mukai, Tomohiko Taguchi
Publikováno v:
Cell Structure and Function. 48:59-70
Stimulator of interferon genes (STING) is an ER-localized transmembrane protein and the receptor for 2',3'-cyclic guanosine monophosphateendash;adenosine monophosphate (cGAMP), which is a second messenger produced by cGAMP synthase (cGAS), a cytosoli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd284aeef5cf54b1e395f177aebf826a
https://doi.org/10.1247/csf.22085
https://doi.org/10.1247/csf.22085
Autor:
Sayaka Oda, Takuro Numaga-Tomita, Naoyuki Kitajima, Takashi Toyama, Eri Harada, Tsukasa Shimauchi, Akiyuki Nishimura, Tatsuya Ishikawa, Yoshito Kumagai, Lutz Birnbaumer, Motohiro Nishida
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Excess production of reactive oxygen species (ROS) caused by hyperglycemia is a major risk factor for heart failure. We previously reported that transient receptor potential canonical 3 (TRPC3) channel mediates pressure overload-induced mala
Externí odkaz:
https://doaj.org/article/1d2ac9be588947d783316c98deccb3ba
Low temperature synthesis of aluminum nitride from anhydrous aluminum chloride-organic amine complex
Publikováno v:
Journal of the Ceramic Society of Japan. 130:707-714
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88a5e6aa7186f45d75715a9700e4a5c2
https://doi.org/10.2109/jcersj2.22041
https://doi.org/10.2109/jcersj2.22041
Autor:
Takashi Toyama, Sidi Xu, Yoshitomi Kanemitsu, Takashi Hasegawa, Takuya Noguchi, Jin-Yong Lee, Atsushi Matsuzawa, Akira Naganuma, Gi-Wook Hwang
Publikováno v:
Archives of Toxicology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10b89578542f871dd0f8521872337013
https://doi.org/10.1007/s00204-023-03520-5
https://doi.org/10.1007/s00204-023-03520-5
Publikováno v:
BPB Reports. 5:74-79
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c583980c4f97146135aa89a3dc9cc85
https://doi.org/10.1248/bpbreports.5.4_74
https://doi.org/10.1248/bpbreports.5.4_74