Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Takashi, Shimokawa"'
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/18d84c74f7fc4936a6efc1e015ab2617
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The effects of Carbon ion radiation (C-ion) alone or in combination with fused toes homolog (FTS) silencing on Notch signaling were investigated in uterine cervical cancer cell lines (ME180 and CaSki). In both cell lines, upon irradiation with C-ion,
Externí odkaz:
https://doaj.org/article/b494205be51d4fb2bf14a06d01a9f0a5
Autor:
Lulu Zhang, Yihai Cao, Lin Xie, Ming-Rong Zhang, Kuan Hu, Yanhong Duo, Takashi Shimokawa, Katsushi Kumata, Yiding Zhang, Cuiping Jiang, Nobuki Nengaki, Hidekatsu Wakizaka
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Background Indoleamine-2,3-dioxygenase 1 (IDO1) has been intensively pursued as a therapeutic target to reverse the immunosuppressive cancer-immune milieu and promote tumor elimination. However, recent failures of phase III clinical trials with IDO1
Externí odkaz:
https://doaj.org/article/0cf1076d0abc42ddb32111deb107daf7
Autor:
Akinori Morita, Bing Wang, Kaoru Tanaka, Takanori Katsube, Masahiro Murakami, Takashi Shimokawa, Yuichi Nishiyama, Shintaro Ochi, Hidetoshi Satoh, Mitsuru Nenoi, Shin Aoki
Publikováno v:
Frontiers in Public Health, Vol 8 (2020)
Radiation damage to normal tissues is one of the most serious concerns in radiation therapy, and the tolerance dose of the normal tissues limits the therapeutic dose to the patients. p53 is well known as a transcription factor closely associated with
Externí odkaz:
https://doaj.org/article/088a697ee94041e89325b14a23b3a05d
Publikováno v:
Cancer Science. 114:1108-1117
DNA double-strand breaks (DSBs) seriously damage DNA and promote genomic instability that can lead to cell death. They are the source of conditions such as carcinogenesis and aging, but also have important applications in cancer therapy. Therefore, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6e03486336f4b49c193a3adf4f255a
https://doi.org/10.1111/cas.15659
https://doi.org/10.1111/cas.15659
Autor:
Tomoya Hosoguchi, Yuna Uchiyama, Hinata Komazawa, Masaki Yahata, Takashi Shimokawa, Akiyoshi Tominaga
Publikováno v:
Plants, Vol 10, Iss 7, p 1480 (2021)
Gerbera in vitro shoots were irradiated using three types of ion beams with different line energy transfers (LETs) to investigate the effective LET and absorbed doses for mutagenesis. Furthermore, genomic mutation analyses were conducted on the obtai
Externí odkaz:
https://doaj.org/article/af1e842c9dae424589b65ba4298d13b7
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
In recent years, advanced radiation therapy techniques, including stereotactic body radiotherapy and carbon–ion radiotherapy, have progressed to such an extent that certain types of cancer can be treated with radiotherapy alone. The therapeutic out
Externí odkaz:
https://doaj.org/article/3a5c34aab0f94442bfd34c56407e12b1
Autor:
Takashi Shimokawa, Takashi Imai, Akihisa Takahashi, Tsuguhide Takeshima, Hiromi Otsuka, Ken Ando, Liqiu Ma, Kazuhiro Kakimi, Yoshimitsu Sakamoto, Daniel K. Ebner, Hidetoshi Fujita
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 112:780-789
Purpose: The goal of this study is to clarify the underlying mechanisms of metastasis suppression by CiDC (carbon-ion radiotherapy (CIRT) combined with immature dendritic cell (iDC) immunotherapy), which was previously shown to significantly suppress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17095e25e6df987ef3e6714d448953e7
https://doi.org/10.1016/j.ijrobp.2021.10.141
https://doi.org/10.1016/j.ijrobp.2021.10.141
Autor:
Liqiu Ma, Yoshimitsu Sakamoto, Akinori Kanai, Hiromi Otsuka, Akihisa Takahashi, Kazuhiro Kakimi, Takashi Imai, Takashi Shimokawa
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8, p 2829 (2020)
The establishment of cancer cell lines, which have different metastatic abilities compared with the parental cell, is considered as an effective approach to investigate mechanisms of metastasis. A highly metastatic potential mouse colon cancer cell s
Externí odkaz:
https://doaj.org/article/568bddbb899d42808dafa4e44a7dad96
Autor:
Ma, Liqiu, Sakamoto, Yoshimitsu, Ando, Ken, Fujita, Hidetoshi, Takahashi, Akihisa, Takeshima, Tsuguhide, Otsuka, Hiromi, K Ebner, Daniel, Kakimi, Kazuhiro, Imai, Takashi, Shimokawa, Takashi, Yoshimitsu, Sakamoto, Ken, Ando, Hidetoshi, Fujita, Akihisa, Takahashi, Tsuguhide, Takeshima, Ebner, Daniel, Takashi, Imai, Takashi, Shimokawa
Publikováno v:
International journal of radiation oncology, biology, physics. 112(3):780-789
The goal of this study is to clarify the underlying mechanisms of metastasis suppression by carbon-ion radiotherapy combined with immature dendritic cell immunotherapy (CiDC), which was shown previously to suppress pulmonary metastasis in an NR-S1-be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::47d6143b5381bb7200d3554808964315
https://repo.qst.go.jp/records/85044
https://repo.qst.go.jp/records/85044