Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Takashi, Saitou"'
Autor:
Yusuke Okujima, Takao Watanabe, Takeshi Ito, Yasumichi Inoue, Yutaka Kasai, Yusuke Imai, Yoshiko Nakamura, Mitsuhito Koizumi, Osamu Yoshida, Yoshio Tokumoto, Masashi Hirooka, Masanori Abe, Ryosuke Kawakami, Takashi Saitou, Takeshi Imamura, Yoshinori Murakami, Yoichi Hiasa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract RNA-dependent protein kinase (PKR) may have a positive regulatory role in controlling tumor growth and progression in hepatocellular carcinoma (HCC). However, the downstream substrates and the molecular mechanism of PKR in the growth and pro
Externí odkaz:
https://doaj.org/article/dd42980cfe6a449483d6c8e426e3ad7c
Autor:
Motoki Tamura, Ryota Ishikawa, Yuki Nakanishi, Juan Pascual-Anaya, Makiko Fukui, Takashi Saitou, Fumiaki Sugahara, Filippo M. Rijli, Shigeru Kuratani, Daichi G. Suzuki, Yasunori Murakami
Publikováno v:
Zoological Letters, Vol 9, Iss 1, Pp 1-14 (2023)
Abstract The evolutionary origin of the jaw remains one of the most enigmatic events in vertebrate evolution. The trigeminal nerve is a key component for understanding jaw evolution, as it plays a crucial role as a sensorimotor interface for the effe
Externí odkaz:
https://doaj.org/article/bde9a43fe6224220b93d3a215aca3ce5
Autor:
Yutaka Nakamura, Mitsuru Saitou, Shingo Komura, Kazu Matsumoto, Hiroyasu Ogawa, Takaki Miyagawa, Takashi Saitou, Takeshi Imamura, Yuuki Imai, Hiroshi Takayanagi, Haruhiko Akiyama
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Developmental dysplasia of the hip (DDH) is characterized by anatomical abnormalities of the hip joint, ranging from mild acetabular dysplasia to hip subluxation and eventually dislocation. The mechanism underlying the cartilage degeneration
Externí odkaz:
https://doaj.org/article/67d23bc7b5df42918222feb2cd685fa6
Autor:
Sakirul Khan, Akihide Takeuchi, Hiroaki Nabeka, Farzana Khan, Tetsuya Shimokawa, Sota Takanezawa, Takashi Saitou, Takeshi Imamura, Tetsuya Tachibana, Akira Nishizono, Fumihiko Hamada, Seiji Matsuda
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106277- (2023)
Summary: Neural tube defects (NTDs) cause fetal and pediatric deaths or lifelong neurological disabilities. No effective treatment is currently available for NTDs. We attempted to elucidate the pathogenesis of NTDs and propose a therapeutic strategy.
Externí odkaz:
https://doaj.org/article/128380307a99435e8ad3e3918d24e6fe
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Here, the authors present a two-photon light-sheet microscopy with an extended Bessel beam for a tunable field of view and reduced photodamage. They demonstrate long-term imaging of cellular dynamics over the whole body of medaka fish.
Externí odkaz:
https://doaj.org/article/90559b29e26841108de03ff6b2703874
Autor:
Junichi Kushioka, Takashi Kaito, Rintaro Okada, Hiroyuki Ishiguro, Zeynep Bal, Joe Kodama, Ryota Chijimatsu, Melanie Pye, Masahiro Narimatsu, Jeffrey L. Wrana, Yasumichi Inoue, Hiroko Ninomiya, Shin Yamamoto, Takashi Saitou, Hideki Yoshikawa, Takeshi Imamura
Publikováno v:
Bone Research, Vol 8, Iss 1, Pp 1-10 (2020)
Abstract Transforming growth factor-β (TGF-β) and bone morphogenetic protein (BMP) play important roles in bone metabolism. Smad ubiquitination regulatory factors (Smurfs) regulate TGF-β/BMP signaling via ubiquitination, resulting in degradation o
Externí odkaz:
https://doaj.org/article/486bd53363764461b17c581167aaf5a8
Autor:
Kana Kobayashi-Taguchi, Takashi Saitou, Yoshiaki Kamei, Akari Murakami, Kanako Nishiyama, Reina Aoki, Erina Kusakabe, Haruna Noda, Michiko Yamashita, Riko Kitazawa, Takeshi Imamura, Yasutsugu Takada
Publikováno v:
Molecules, Vol 27, Iss 10, p 3340 (2022)
Fibroadenomas (FAs) and phyllodes tumors (PTs) are major benign breast tumors, pathologically classified as fibroepithelial tumors. Although the clinical management of PTs differs from FAs, distinction by core needle biopsy diagnoses is still challen
Externí odkaz:
https://doaj.org/article/5c516d29c5ea4df8990f41ee1ac5e44b
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Osteoarthritis (OA) is a chronic joint disorder involving degeneration of articular cartilage and subchondral bone in joints. We previously established a second harmonic generation (SHG) imaging technique for evaluating degenerative changes
Externí odkaz:
https://doaj.org/article/90dbae1df58543c1a462d5489c64bc05
Autor:
Ji-Won Lee, Akiyoshi Hoshino, Kazuki Inoue, Takashi Saitou, Shunsuke Uehara, Yasuhiro Kobayashi, Satoshi Ueha, Kouji Matsushima, Akira Yamaguchi, Yuuki Imai, Tadahiro Iimura
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
CCR5 is a co-receptor for HIV, and loss of function is associated with lower incidence of HIV but also with bone-destructive diseases. Here the authors show that ablation of CCR5 impairs osteoclast function and improves resistance to osteoporosis in
Externí odkaz:
https://doaj.org/article/6fe7e4dd266040a8baeee5dab56aa280
Autor:
Imamura, Takashi Saitou, Takeshi
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 10186
Two-photon excitation in light-sheet microscopy advances applications to live imaging of multicellular organisms. In a previous study, we developed a two-photon Bessel beam light-sheet microscope with a nearly 1-mm field of view and less than 4-μm a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::fba1148f27ec453059ce245572c3e275