Zobrazeno 1 - 10
of 1 053
pro vyhledávání: '"Takashi, Okada"'
Autor:
Shion Hosoda, Hisashi Iwata, Takuya Miura, Maiko Tanabe, Takashi Okada, Atsushi Mochizuki, Miwa Sato
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-21 (2024)
Abstract Background Chemical bioproduction has attracted attention as a key technology in a decarbonized society. In computational design for chemical bioproduction, it is necessary to predict changes in metabolic fluxes when up-/down-regulating enzy
Externí odkaz:
https://doaj.org/article/a6b021fcc0804e1db510cc5e2c0213ed
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
IntroductionThis study aimed to estimate prevalence and incidence of attention deficit/hyperactivity disorder (ADHD) and comorbid relationships between ADHD and other psychiatric disorders in Japan.MethodsUsing the real-world JMDC Claims Database, we
Externí odkaz:
https://doaj.org/article/96d56d6276d04f6ba40ab6ab3b759735
Autor:
Tzuyao Lo, Itaru Kushima, Hiroki Kimura, Branko Aleksic, Takashi Okada, Hidekazu Kato, Toshiya Inada, Yoshihiro Nawa, Youta Torii, Maeri Yamamoto, Ryo Kimura, Yasuko Funabiki, Hirotaka Kosaka, Shusuke Numata, Kiyoto Kasai, Tsukasa Sasaki, Shigeru Yokoyama, Toshio Munesue, Ryota Hashimoto, Yuka Yasuda, Michiko Fujimoto, Masahide Usami, Masanari Itokawa, Makoto Arai, Kazutaka Ohi, Toshiyuki Someya, Yuichiro Watanabe, Jun Egawa, Tsutomu Takahashi, Michio Suzuki, Hidenori Yamasue, Nakao Iwata, Masashi Ikeda, Norio Ozaki
Publikováno v:
Neuropsychopharmacology Reports, Vol 44, Iss 1, Pp 42-50 (2024)
Abstract Aim The present study aimed to examine the association between copy number variations (CNVs) in parkin (PRKN) and schizophrenia (SCZ) and autism spectrum disorder (ASD) in a large case–control sample. Method Array comparative genomic hybri
Externí odkaz:
https://doaj.org/article/7c5247e49f9446b48f67640ae93b6ce0
Autor:
Masatoshi Ukezono, Yoshiyuki Kasahara, Chihiro Yoshida, Yuki Murakami, Takashi Okada, Yuji Takano
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 18 (2024)
BackgroundA rodent autism spectrum disorder (ASD) model based on prenatal exposure to valproic acid (VPA) is widely recognized as a prominent model. Social behavior in rodent ASD models has primarily been evaluated through a three-chamber approach te
Externí odkaz:
https://doaj.org/article/92299f9990cb4778b690fad96d3462bc
Autor:
Noa Tsujii, Kosuke Okazaki, Hiroaki Kihara, Masahide Usami, Junichi Fujita, Fumie Horiuchi, Takashi Okada, Hideki Negoro
Publikováno v:
PCN Reports, Vol 3, Iss 2, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/4247696fa2bb403fa406079fc7a3e39f
Autor:
Yuko Nitahara-Kasahara, Guillermo Posadas-Herrera, Kunio Hirai, Yuki Oda, Noriko Snagu-Miyamoto, Yuji Yamanashi, Takashi Okada
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
IntroductionDuchenne muscular dystrophy (DMD) is a genetic disorder caused by mutations in the dystrophin-encoding gene that leads to muscle necrosis and degeneration with chronic inflammation during growth, resulting in progressive generalized weakn
Externí odkaz:
https://doaj.org/article/e2a973ee24df45b998f81b57b85e6b1a
Publikováno v:
Biomolecules, Vol 14, Iss 11, p 1477 (2024)
Mitochondrial DNA (mtDNA) supplementation can rescue poor oocyte quality and overcome embryonic arrest. Here, we investigated a series of sexually mature pigs generated through autologous and heterologous mtDNA supplementation. Brain, liver and heart
Externí odkaz:
https://doaj.org/article/aa4ef23b6b5744239aa445a721e115c0
Autor:
QinQin Yu, Joao A Ascensao, Takashi Okada, COVID-19 Genomics UK (COG-UK) Consortium, Olivia Boyd, Erik Volz, Oskar Hallatschek
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1012090 (2024)
Genetic drift in infectious disease transmission results from randomness of transmission and host recovery or death. The strength of genetic drift for SARS-CoV-2 transmission is expected to be high due to high levels of superspreading, and this is ex
Externí odkaz:
https://doaj.org/article/54499924c55b4d6fbf11f47395fc77d6
Autor:
Yuki Motomura, Sayuri Hayashi, Ryousei Kurose, Hiroki Yoshida, Takashi Okada, Shigekazu Higuchi
Publikováno v:
Journal of Physiological Anthropology, Vol 42, Iss 1, Pp 1-14 (2023)
Abstract Background The aim of this study was to examine the effect of others’ gaze on an observer’s microsaccades. We also aimed to conduct preliminary investigations on the relationship between the microsaccadic response to a gaze and a gazer
Externí odkaz:
https://doaj.org/article/81f4742ef07d49749f64e158816b49ee
Autor:
Masafumi Arakawa, Yuki Sakamoto, Yoshitaka Miyagawa, Chikako Nito, Shiro Takahashi, Yuko Nitahara-Kasahara, Satoshi Suda, Yoshiyuki Yamazaki, Mashito Sakai, Kazumi Kimura, Takashi Okada
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 333-349 (2023)
Induced pluripotent stem cell-derived mesenchymal stem cells (iMSCs) hold great promise as a cell source for transplantation into injured tissues to alleviate inflammation. However, the therapeutic efficacy of iMSC transplantation for ischemic stroke
Externí odkaz:
https://doaj.org/article/de77c9267be3494292d9022ead8fa26d