Zobrazeno 1 - 10
of 267
pro vyhledávání: '"Takashi, Ohtsuki"'
Autor:
Takashi Ohtsuki, Yi Huang, Ayane Kamiya, Yuki Nakayama, Miyuki Matsushita, Satoru Morikawa, Hiroshi Matsufuji
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract We developed a reliable high-performance liquid chromatographic analysis method using a relative molar sensitivity (RMS) technique that does not require an authentic, identical reference analyte material to quantify blood serum carbamazepine
Externí odkaz:
https://doaj.org/article/3e65f5fab2bb4bf78c4f7880f4ef47a8
Autor:
Yuka Ikawa, Takuya Wakai, Hiroaki Funahashi, Tet Htut Soe, Kazunori Watanabe, Takashi Ohtsuki
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-6 (2023)
Abstract Single-cell-specific delivery of small RNAs, such as short hairpin RNA (shRNA) and small noncoding RNAs, allows us to elucidate the roles of specific upregulation of RNA expression and RNAi-mediated gene suppression in early embryo developme
Externí odkaz:
https://doaj.org/article/81a0e7c4238b4c78bc879fd8b2544e20
Autor:
Shengli Zhou, Kaname Tsutsumiuchi, Ritsuko Imai, Yukiko Miki, Anna Kondo, Hiroshi Nakagawa, Kazunori Watanabe, Takashi Ohtsuki
Publikováno v:
Molecules, Vol 29, Iss 11, p 2632 (2024)
Cancer cells have higher heat sensitivity compared to normal cells; therefore, hyperthermia is a promising approach for cancer therapy because of its ability to selectively kill cancer cells by heating them. However, the specific and rapid heating of
Externí odkaz:
https://doaj.org/article/c1c7d2e835b74eeea578b30e63cf8f7e
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Methods to spatially induce apoptosis are useful for cancer therapy. To control the induction of apoptosis, methods using light, such as photochemical internalization (PCI), have been developed. We hypothesized that photoinduced delivery of
Externí odkaz:
https://doaj.org/article/e89e738ac0294ecab0e853010feb3939
Autor:
Yoshiyuki Hakata, Kazuma Yamashita, Sonoko Hashimoto, Takashi Ohtsuki, Masaaki Miyazawa, Mizuki Kitamatsu
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1048 (2023)
A connection of a functional peptide with a cell-penetrating peptide (CPP) used a heterodimeric coiled-coil as a molecular zipper can improve the intracellular delivery and activity of the functional peptide. However, the chain length of the coiled c
Externí odkaz:
https://doaj.org/article/1f3c12d4798d404d9e0b8ce6e174dfa7
Autor:
Abdul Basith Fithroni, Kazuko Kobayashi, Hirotaka Uji, Manabu Ishimoto, Masaru Akehi, Takashi Ohtsuki, Eiji Matsuura
Publikováno v:
Cells, Vol 11, Iss 20, p 3307 (2022)
BNCT is a non-invasive cancer therapy that allows for cancer cell death without harming adjacent cells. However, the application is limited, owing to the challenges of working with clinically approved boron (B) compounds and drug delivery systems (DD
Externí odkaz:
https://doaj.org/article/68a8bfb420814ca387b6702d77dde302
Autor:
Hanqiao Xu, Nobumichi Ohoka, Hidetomo Yokoo, Kanako Nemoto, Takashi Ohtsuki, Hiroshi Matsufuji, Mikihiko Naito, Takao Inoue, Genichiro Tsuji, Yosuke Demizu
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Liver X receptors (LXRs) belong to the nuclear hormone receptor superfamily and function as ligand-dependent transcription factors that regulate cholesterol homeostasis, lipid homeostasis, and immune responses. LXR antagonists are promising treatment
Externí odkaz:
https://doaj.org/article/ae88e5afc088454faabd03455637e750
Publikováno v:
The Journal of Japan Society for Laser Surgery and Medicine. 44:62-68
Publikováno v:
ACS Omega, Vol 3, Iss 12, Pp 17287-17294 (2018)
Externí odkaz:
https://doaj.org/article/f5d80a00696a4edeaeaf906d434b1b67
Publikováno v:
Analyst. 148(11):2626-2632
Technologies for visualizing and tracking RNA are essential in molecular biology, including in disease-related fields. In this study, we propose a novel probe set (DAt-probe and T-probe) that simultaneously detects two mutations in the same RNA using