Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Takashi, Kagari"'
Autor:
Toshihiko Doi, Yasuhiro Matsumura, Masahiro Yasunaga, Kenji Hirotani, Takashi Kagari, Naoyuki Maeda, Mayumi Yamauchi, Takashi Kojima, Yoshikatsu Koga, Yasutoshi Kuboki, Shigehiro Koganemaru
Body weight changes in tumor-xenografted mice treated with U3-1402.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::504eefbac9bcd74cca356bcd78ecefd0
https://doi.org/10.1158/1535-7163.22505760.v1
https://doi.org/10.1158/1535-7163.22505760.v1
Autor:
Kazuhiko Nakagawa, Kazuto Nishio, Takashi Kagari, Kenji Hirotani, Yuuri Hashimoto, Masanori Funabashi, Ryoto Yoshimoto, Maki Kobayashi, Hiroaki Okida, Eri Otsuka, Hiroki Goto, Asuka Tsuya, Yasutaka Chiba, Kazuko Sakai, Hidetoshi Hayashi, Kaoru Tanaka, Hisato Kawakami, Koji Haratani, Osamu Maenishi, Junko Tanizaki, Kimio Yonesaka
Supplementary Table from HER3 Augmentation via Blockade of EGFR/AKT Signaling Enhances Anticancer Activity of HER3-Targeting Patritumab Deruxtecan in EGFR-Mutated Non–Small Cell Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193a3c11e4e3e804b1cd4a8031602911
https://doi.org/10.1158/1078-0432.22487915.v1
https://doi.org/10.1158/1078-0432.22487915.v1
Autor:
Kazuhiko Nakagawa, Kazuto Nishio, Takashi Kagari, Kenji Hirotani, Yuuri Hashimoto, Masanori Funabashi, Ryoto Yoshimoto, Maki Kobayashi, Hiroaki Okida, Eri Otsuka, Hiroki Goto, Asuka Tsuya, Yasutaka Chiba, Kazuko Sakai, Hidetoshi Hayashi, Kaoru Tanaka, Hisato Kawakami, Koji Haratani, Osamu Maenishi, Junko Tanizaki, Kimio Yonesaka
Supplementary Figure from HER3 Augmentation via Blockade of EGFR/AKT Signaling Enhances Anticancer Activity of HER3-Targeting Patritumab Deruxtecan in EGFR-Mutated Non–Small Cell Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318557b3f697f81f5990207a8834d461
https://doi.org/10.1158/1078-0432.22487939.v1
https://doi.org/10.1158/1078-0432.22487939.v1
Autor:
Toshinori Agatsuma, Suguru Ueno, Masato Murakami, Yuki Abe, Takashi Kagari, Kenichi Wakita, Taisei Nomura, Takashi Nakada, Koji Morita, Ichiro Hayakawa, Tsuyoshi Karibe, Tomomichi Ishizaka, Takuma Iguchi, Yoshinobu Shiose, Naoyuki Maeda, Yuki Kaneda, Manabu Abe, Akiko Zembutsu, Yusuke Ogitani, Kenji Hirotani, Yasuki Kamai, Kumiko Koyama, Yuuri Hashimoto
Growth inhibition activity in 8 cell lines with different HER3 expression levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880231614c871ee8daf9d171aeb6f711
https://doi.org/10.1158/1078-0432.22471701
https://doi.org/10.1158/1078-0432.22471701
Autor:
Toshinori Agatsuma, Suguru Ueno, Masato Murakami, Yuki Abe, Takashi Kagari, Kenichi Wakita, Taisei Nomura, Takashi Nakada, Koji Morita, Ichiro Hayakawa, Tsuyoshi Karibe, Tomomichi Ishizaka, Takuma Iguchi, Yoshinobu Shiose, Naoyuki Maeda, Yuki Kaneda, Manabu Abe, Akiko Zembutsu, Yusuke Ogitani, Kenji Hirotani, Yasuki Kamai, Kumiko Koyama, Yuuri Hashimoto
Cell surface expression of HER3 and HER2 on human cancer cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d196b076a66226bf5f6c138392bf157
https://doi.org/10.1158/1078-0432.22471704.v1
https://doi.org/10.1158/1078-0432.22471704.v1
Autor:
Toshinori Agatsuma, Suguru Ueno, Masato Murakami, Yuki Abe, Takashi Kagari, Kenichi Wakita, Taisei Nomura, Takashi Nakada, Koji Morita, Ichiro Hayakawa, Tsuyoshi Karibe, Tomomichi Ishizaka, Takuma Iguchi, Yoshinobu Shiose, Naoyuki Maeda, Yuki Kaneda, Manabu Abe, Akiko Zembutsu, Yusuke Ogitani, Kenji Hirotani, Yasuki Kamai, Kumiko Koyama, Yuuri Hashimoto
Purpose:HER3 is a compelling target for cancer treatment; however, no HER3-targeted therapy is currently clinically available. Here, we produced U3-1402, an anti-HER3 antibody–drug conjugate with a topoisomerase I inhibitor exatecan derivative (DXd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d33bfc877155e5b7eac75bca137859
https://doi.org/10.1158/1078-0432.c.6527970.v1
https://doi.org/10.1158/1078-0432.c.6527970.v1
Autor:
Toshinori Agatsuma, Suguru Ueno, Masato Murakami, Yuki Abe, Takashi Kagari, Kenichi Wakita, Taisei Nomura, Takashi Nakada, Koji Morita, Ichiro Hayakawa, Tsuyoshi Karibe, Tomomichi Ishizaka, Takuma Iguchi, Yoshinobu Shiose, Naoyuki Maeda, Yuki Kaneda, Manabu Abe, Akiko Zembutsu, Yusuke Ogitani, Kenji Hirotani, Yasuki Kamai, Kumiko Koyama, Yuuri Hashimoto
Summary of repeated dose toxicity studies in rats and monkeys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31345a27ba184e20db8d45cca77a20fe
https://doi.org/10.1158/1078-0432.22471692.v1
https://doi.org/10.1158/1078-0432.22471692.v1
Autor:
Toshinori Agatsuma, Suguru Ueno, Masato Murakami, Yuki Abe, Takashi Kagari, Kenichi Wakita, Taisei Nomura, Takashi Nakada, Koji Morita, Ichiro Hayakawa, Tsuyoshi Karibe, Tomomichi Ishizaka, Takuma Iguchi, Yoshinobu Shiose, Naoyuki Maeda, Yuki Kaneda, Manabu Abe, Akiko Zembutsu, Yusuke Ogitani, Kenji Hirotani, Yasuki Kamai, Kumiko Koyama, Yuuri Hashimoto
Supplementary materials and methods for xenograft studies and IHC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317dd6d312800e53a11d97fafe984b3c
https://doi.org/10.1158/1078-0432.22471695
https://doi.org/10.1158/1078-0432.22471695
Autor:
Kazuhiko Nakagawa, Kazuto Nishio, Takashi Kagari, Kenji Hirotani, Yuuri Hashimoto, Masanori Funabashi, Ryoto Yoshimoto, Maki Kobayashi, Hiroaki Okida, Eri Otsuka, Hiroki Goto, Asuka Tsuya, Yasutaka Chiba, Kazuko Sakai, Hidetoshi Hayashi, Kaoru Tanaka, Hisato Kawakami, Koji Haratani, Osamu Maenishi, Junko Tanizaki, Kimio Yonesaka
Purpose:EGFR-tyrosine kinase inhibitor (TKI) is a standard first-line therapy for activated EGFR-mutated non–small cell lung cancer (NSCLC). Treatment options for patients with acquired EGFR-TKI resistance are limited. HER3 mediates EGFR-TKI resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c6ed051d8ae4eb6ca20cb9d295f077e
https://doi.org/10.1158/1078-0432.c.6532610.v1
https://doi.org/10.1158/1078-0432.c.6532610.v1
Autor:
Toshinori Agatsuma, Suguru Ueno, Masato Murakami, Yuki Abe, Takashi Kagari, Kenichi Wakita, Taisei Nomura, Takashi Nakada, Koji Morita, Ichiro Hayakawa, Tsuyoshi Karibe, Tomomichi Ishizaka, Takuma Iguchi, Yoshinobu Shiose, Naoyuki Maeda, Yuki Kaneda, Manabu Abe, Akiko Zembutsu, Yusuke Ogitani, Kenji Hirotani, Yasuki Kamai, Kumiko Koyama, Yuuri Hashimoto
Antitumor activity of U3-1402 in HER3-positive HCC1569 and MDA-MB-453 xenograft models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76515d7e683828132d78db8334c31315
https://doi.org/10.1158/1078-0432.22471698.v1
https://doi.org/10.1158/1078-0432.22471698.v1