Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Takashi, Inui"'
Autor:
Chisato Tanaka, Naoki Harada, Yoshiaki Teraoka, Hiroki Urushizaki, Yoh Shinmori, Teruaki Onishi, Yusuke Yotsumoto, Yuta Ito, Tomoya Kitakaze, Takashi Inui, Yuji Murata, Hiroshi Inui, Ryoichi Yamaji
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Target identification is a crucial step in elucidating the mechanisms by which functional food components exert their functions. Here, we identified the G-protein-coupled bile acid receptor 1 (GPBAR1, also known as TGR5) as a target of the t
Externí odkaz:
https://doaj.org/article/99b467968bce4d39b54ac8314d6bfb3e
Autor:
Masatoshi Nakatsuji, Natsuki Sato, Shiho Sakamoto, Koji Watanabe, Yoko Teruuchi, Minoru Takeuchi, Takashi Inui, Hideki Ishihara
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Bacterial aggregation by mixing with polymers is applied as pretreatment to identify pathogens in patients with infectious diseases. However, the detailed interaction between polymers and bacteria has yet to be fully understood. Here, we inv
Externí odkaz:
https://doaj.org/article/44f59f7a8e1645a1b554d08f3d073289
Autor:
Akira Imamura, Tetsuya Okada, Hikaru Mase, Takuya Otani, Tomoka Kobayashi, Manatsu Tamura, Bruno Kilunga Kubata, Katsuaki Inoue, Robert P. Rambo, Susumu Uchiyama, Kentaro Ishii, Shigenori Nishimura, Takashi Inui
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Trypanosoma brucei guanosine 5′-monophosphate reductase (TbGMPR) catalyses the conversion of GMP to inosine 5′-monophosphate and contains a cystathionine-β-synthase (CBS) domain. Here the authors combine X-ray crystallography and kinetic measure
Externí odkaz:
https://doaj.org/article/285564165cb4499dbcb3b1543a57c253
Autor:
Osamu Ishibashi, Mika Hayashi, Aya Horikawa, Hitoshi Owada, Ryotaro Miyamoto, Naoya Mizukami, Takashi Inui
Publikováno v:
Non-Coding RNA, Vol 8, Iss 3, p 43 (2022)
Podocytes, alternatively called glomerular epithelial cells, are terminally differentiated cells that wrap around glomerular capillaries and function as a part of the glomerular filtration barrier in the kidney. Therefore, podocyte injury with morpho
Externí odkaz:
https://doaj.org/article/133e46b3976041888252d085e9fa714c
Autor:
Tomoo Jikuzono, Aya Horikawa, Tomoko Ishikawa, Mitsuyoshi Hirokawa, Iwao Sugitani, Takashi Inui, Osamu Ishibashi
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-6 (2018)
Abstract Objective Fine-needle aspiration biopsy (FNAB), an important diagnostic tool given its simplicity, safety, and cost-effectiveness, is fast becoming a popular procedure in the diagnosis of thyroid diseases. Generally, cells isolated from biop
Externí odkaz:
https://doaj.org/article/d6746630e4de440ca7b697b289e3a952
Autor:
Tsutomu Takeuchi, Nobuyuki Miyasaka, Takashi Inui, Toshiro Yano, Toru Yoshinari, Tohru Abe, Takao Koike
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-11 (2017)
Abstract Background Although both rheumatoid factor (RF) and anticyclic citrullinated peptide antibodies (anti-CCP) are useful for diagnosing rheumatoid arthritis (RA), the impact of these autoantibodies on the efficacy of tumor necrosis factor (TNF)
Externí odkaz:
https://doaj.org/article/03209e4a4150436186284aa8ff8451c0
Publikováno v:
Data in Brief, Vol 23, Iss , Pp - (2019)
Macrophages are classified mainly into two subtypes, M1 and M2, which exhibit distinct phenotypes, based on their microenvironment. We have recently demonstrated that Gpr137b is abundantly expressed in RAW264 macrophages, “Gpr137b is an orphan G-pr
Externí odkaz:
https://doaj.org/article/9a83b05d5bf742cfbe7fb2f827c3d0d5
Publikováno v:
The FEBS Journal.
Thermodynamic stability of human lipocalin-type prostaglandin D synthase under various pH conditions
Autor:
Tsukimi Iida, Masatoshi Nakatsuji, Yoshiaki Teraoka, Yuji Goto, Takaki Yamamura, Takashi Inui
Publikováno v:
The Journal of Biochemistry.
Lipocalin-type prostaglandin D synthase (L-PGDS) binds various hydrophobic small molecules. Since we aim to use human L-PGDS as a carrier in a drug delivery system (DDS) for poorly water-soluble drugs, quality control of the protein is indispensable.