Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Takaoki, Koyanagi"'
Autor:
Ju-Young Lee, Jin Han Nam, Youngpyo Nam, Hye Yeon Nam, Gwangho Yoon, Eunhwa Ko, Sang-Bum Kim, Mahealani R Bautista, Christina C Capule, Takaoki Koyanagi, Geoffray Leriche, Hwan Geun Choi, Jerry Yang, Jeongyeon Kim, Hyang-Sook Hoe
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-23 (2018)
Abstract Background Neuroinflammation is associated with neurodegenerative diseases, including Alzheimer’s disease (AD). Thus, modulating the neuroinflammatory response represents a potential therapeutic strategy for treating neurodegenerative dise
Externí odkaz:
https://doaj.org/article/dfda851a974a40adb2093666dc7b1d5f
Publikováno v:
The Journal of Organic Chemistry. 85:1115-1125
The rate constants for the aqueous reaction, between pH 0 and 14, have been determined for a series of amide substituted N-(hydroxybenzyl)benzamide derivatives, in H2O, at 25 °C, I = 1.0 M (KCl). T...
Autor:
Loren Jon, Ananda Herath, Andrew Valiere, Jim Yuchen Chang, Ashley Chong, Takaoki Koyanagi, Valentina Molteni, Maxim Ratnikov
Publikováno v:
Organic Letters. 21:816-820
A one-pot electrochemical nickel-catalyzed decarboxylative sp2–sp3 cross-coupling reaction has been developed using redox-active esters prepared in situ from alkyl carboxylates and N-hydroxyphthalimide tetramethyluronium hexafluorophosphate (PITU).
Autor:
Gregory P. Holland, Jerry Yang, Geoffray Leriche, Takaoki Koyanagi, Dillan Stengel, David Onofrei
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
A major challenge in liposomal research is to minimize the leakage of encapsulated cargo from either uncontrolled passive permeability across the liposomal membrane or upon fusion with other membranes. We previously showed that liposomes made from pu
Autor:
Takaoki Koyanagi, Kate L. Edler, Raleigh W. Parrott II, Shawn R. Hitchcock, Gregory M. Ferrence
Publikováno v:
Acta Crystallographica Section E, Vol 66, Iss 4, Pp o898-o899 (2010)
In the title compound, C23H31NO2, the lone pair on the nitrogen atom is oriented to facilitate intramolecular hydrogen bonding with the hydroxy group residing on the phenyl substituent. The five-membered ring adopts an envelope confornmation with the
Externí odkaz:
https://doaj.org/article/353e4600c47245bc8ecc978f9ee6d038
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:4319-4322
Although liposomal nanoparticles are one of the most versatile class of drug delivery systems, stable liposomal formulation of small neutral drug molecules still constitutes a challenge due to the low drug retention of current lipid membrane technolo
Autor:
Takaoki, Koyanagi, Ananda, Herath, Ashley, Chong, Maxim, Ratnikov, Andrew, Valiere, Jim, Chang, Valentina, Molteni, Jon, Loren
Publikováno v:
Organic letters. 21(3)
A one-pot electrochemical nickel-catalyzed decarboxylative sp
Autor:
Jerry Yang, David Sept, Young Hun Kim, Kaifu Gao, Michael Mayer, Michael K. Gilson, David Onofrei, Nathan C. Gianneschi, Anirvan Guha, Joseph P. Patterson, Gregory P. Holland, Geoffray Leriche, Takaoki Koyanagi, Karthik Diraviyam
Publikováno v:
Science Advances
Restricted rotation through tethering of lipids as found in archaea helps maintain barrier function at elevated temperatures.
Maintaining membrane integrity is a challenge at extreme temperatures. Biochemical synthesis of membrane-spanning lipid
Maintaining membrane integrity is a challenge at extreme temperatures. Biochemical synthesis of membrane-spanning lipid
Autor:
Michael Mayer, Gregory P. Holland, Takaoki Koyanagi, Geoffray Leriche, Jerry Yang, David Onofrei
Publikováno v:
Angewandte Chemie (International ed. in English), vol 55, iss 5
Koyanagi, T; Leriche, G; Onofrei, D; Holland, GP; Mayer, M; & Yang, J. (2016). Cyclohexane Rings Reduce Membrane Permeability to Small Ions in Archaea-Inspired Tetraether Lipids. Angewandte Chemie-International Edition. doi: 10.1002/anie.201510445. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/7f09f8gx
Koyanagi, T; Leriche, G; Onofrei, D; Holland, GP; Mayer, M; & Yang, J. (2016). Cyclohexane Rings Reduce Membrane Permeability to Small Ions in Archaea-Inspired Tetraether Lipids. Angewandte Chemie-International Edition. doi: 10.1002/anie.201510445. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/7f09f8gx
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Extremophile archaeal organisms overcome problems of membrane permeability by producing lipids with structural elements that putatively improve membrane integrity compared to lipids from other life
Autor:
Geoffray Leriche, Gwangho Yoon, Hye Yeon Nam, Jin Han Nam, Kim Sang Bum, Juyoung Lee, Christina C. Capule, Hwan Geun Choi, Jeongyeon Kim, Takaoki Koyanagi, Hyang-Sook Hoe, Eunhwa Ko, Jerry Yang, Mahealani R. Bautista, Youngpyo Nam
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-23 (2018)
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-23 (2018)
Background Neuroinflammation is associated with neurodegenerative diseases, including Alzheimer’s disease (AD). Thus, modulating the neuroinflammatory response represents a potential therapeutic strategy for treating neurodegenerative diseases. Sev