Zobrazeno 1 - 10
of 848
pro vyhledávání: '"Takao Saruta"'
Autor:
Nlandu Roger Ngatu, Maiko K. Okajima, Maki Yokogawa, Ryoji Hirota, Mikiro Takaishi, Masamitsu Eitoku, Basilua Andre Muzembo, Asif Bhati Sabah, Takao Saruta, Mitsuhiko Miyamura, Tatsuo Kaneko, Shigetoshi Sano, Narufumi Suganuma
Publikováno v:
Allergology International, Vol 61, Iss 4, Pp 597-607 (2012)
Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by pruritic and ec- zematous skin lesions. In this study, AD-like disease was induced in NC/Nga mice so as to evaluate the antiallergic effects of Vernonia amygda
Externí odkaz:
https://doaj.org/article/b9574e7ef09240bb83135430f841f2f6
Publikováno v:
Journal of Pharmacological Sciences, Vol 100, Iss 1, Pp 29-33 (2006)
Abstract.: Rho/Rho-kinase plays an important role not only in the vasoconstrictor mechanism but also in cellular morphology, motility, adhesion, and proliferation. This pathway also serves to modulate the structure and function of various kidney cell
Externí odkaz:
https://doaj.org/article/24e7d75d2b4e427aa3e5a1235e97a1fc
Publikováno v:
Journal of Pharmacological Sciences, Vol 99, Iss 3, Pp 221-227 (2005)
Since conventional Ca2+ antagonists, with predominant blockade of L-type voltage-dependent Ca2+ channels, elicit preferential dilation of afferent arterioles, they might ostensibly aggravate glomerular hypertension. Recently, novel Ca2+ antagonists,
Externí odkaz:
https://doaj.org/article/0300bb811c6a4cc0aa24f81e3692e033
Autor:
Kazuo, Kitagawa, Hisatomi, Arima, Yasumasa, Yamamoto, Shinichiro, Ueda, Hiromi, Rakugi, Takahide, Kohro, Koji, Yonemoto, Masayasu, Matsumoto, Takao, Saruta, Kazuyuki, Shimada, Seigo, Nakada
Publikováno v:
Hypertension research : official journal of the Japanese Society of Hypertension. 45(4)
The Recurrent Stroke Prevention Clinical Outcome (RESPECT) Study and its pooled analysis showed that intensive blood pressure (BP) lowering reduced recurrent stroke risk by 22% in patients with a history of stroke. Here, we report the effect of inten
Autor:
Milad Nazarzadeh, Morris J. Brown, Anthony Rodgers, Henry R. Black, Takao Saruta, Hiromichi Suzuki, Sverre E. Kjeldsen, Barry R. Davis, Anushka Patel, Edmund J. Lewis, John B. Kostis, Stevo Julius, Giuseppe Remuzzi, Jan A. Staessen, Stephan Lueders, Lutgarde Thijs, Ji-Guang Wang, Jan Lanke, Rory Collins, Amanda I Adler, Ray Estacio, Gianpaolo Reboldi, Yoshiki Yui, Yoshihiko Kanno, Michel Lievre, Ajay Gupta, Hiroshi Ogawa, Piero Ruggenenti, Maria H Mehlum, Peter Sleight, Craig S. Anderson, Tsuguya Fukui, Ale Algra, Jamie P. Dwyer, William C. Cushman, MA Pfeffer, Ettore Malacco, Julia B. Lewis, Kenji Ueshima, Peter S. Sever, Lars H Lindholm, Steven E. Nissen, Larry Agodoa, Dexter Canoy, Christopher J. Bulpitt, Robert P Byington, Zeinab Bidel, Richard J McManus, Giancarlo Viberti, N Beckett, Jasper J Brugts, Eivind Berge, Frank P. Brouwers, Jacobus Lubsen, Robert W. Schrier, Johan Sundström, Salim Yusuf, Lindon Wing, Zhen-Yu Zhang, Paul K. Whelton, Colin Baigent, Alberto Zanchetti, Toshio Ogihara, Barry M. Brenner, Jeffrey Cutler, Bruce Neal, Paolo Verdecchia, Dick de Zeeuw, Stephen MacMahon, Takayoshi Ohkubo, Emma Copland, Wiek H. van Gilst, Folkert W. Asselbergs, Neil R Poulter, Kristian Wachtell, Vlado Perkovic, Kazem Rahimi, Christopher M. Reid, Peter M. Rothwell, Seiji Umemoto, Hiromi Rakugi, Koon K. Teo, Kim Fox, Malgorzata Wamil, Masao Ishii, Mark Woodward, Fiona Turnbull, Kizuku Kuramoto, Richard B Devereaux, Christopher R. Palmer, Joachim Schrader, Carl J. Pepine, Robert Fagard, Giuseppe Mancia, Rury R. Holman, Masunori Matsuzaki, Eric Boersma, John Chalmers, Jeannette Majert, Gholamreza Salimi-Khorshidi, Bertram Pitt, Yutaka Imai
Publikováno v:
The Lancet, 398(10305), 1053-1064. Elsevier Ltd.
Background The effects of pharmacological blood-pressure-lowering on cardiovascular outcomes in individuals aged 70 years and older, particularly when blood pressure is not substantially increased, is uncertain. We compared the effects of blood-press
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b32b7994875e1d4ad1d2b712dd71cf4f
https://doi.org/10.1016/s0140-6736(21)01921-8
https://doi.org/10.1016/s0140-6736(21)01921-8
Autor:
Yoshiki Yui, Barry M. Brenner, Lutgarde Thijs, Stevo Julius, Seiji Umemoto, Peter M. Rothwell, Kristian Wachtell, Yutaka Imai, Giuseppe Remuzzi, Masao Ishii, Robert W. Schrier, Hiromi Rakugi, Ajay Gupta, Piero Ruggenenti, Mark Woodward, Ana-Catarina Pinho-Gomes, Paolo Verdecchia, Stephen MacMahon, Gholamreza Salimi-Khorshidi, Michel Lievre, Vlado Perkovic, Koon K. Teo, Neil R Poulter, Christopher M. Reid, Anthony Rodgers, Lindon Wing, Peter Sleight, Maria H Mehlum, Giancarlo Viberti, Ray Estacio, Jeffrey Cutler, Paul K. Whelton, Steven E. Nissen, Giuseppe Mancia, Bruce Neal, Milad Nazarzadeh, Ettore Malacco, Morris J. Brown, Kim Fox, Yoshihiko Kanno, Kenji Ueshima, Alberto Zanchetti, Toshio Ogihara, Craig S. Anderson, Anushka Patel, Masunori Matsuzaki, Jan Lanke, Fiona Turnbull, Gianpaolo Reboldi, Ale Algra, Kizuku Kuramoto, Richard B Devereaux, Larry Agodoa, Henry R. Black, John Chalmers, Colin Baigent, Christopher J. Bulpitt, Hiromichi Suzuki, Rory Collins, Robert Fagard, Edmund J. Lewis, Hiroshi Ogawa, Dick de Zeeuw, Tsuguya Fukui, Julia B Lewis, MA Pfeffer, Robert P Byington, John B. Kostis, Jan A. Staessen, Stephan Lueders, Amanda I Adler, Eivind Berge, William C. Cushman, Frank P. Brouwers, Lars H Lindholm, Dexter Canoy, Carl J. Pepine, Ji-Guang Wang, Emma Copland, Wiek H. van Gilst, Sverre E. Kjeldsen, Rema Ramakrishnan, Rury R. Holman, Peter S. Sever, Jamie P. Dwyer, Folkert W. Asselbergs, Zeinab Bidel, Takao Saruta, Nigel S Beckett, Christopher R. Palmer, Joachim Schrader, Bertram Pitt, Barry R. Davis, Johan Sundström, Salim Yusuf, Takayoshi Ohkubo, Jacobus Lubsen, Zhen-Yu Zhang, Kazem Rahimi
Publikováno v:
The Lancet, 397(10285), 1625-1636. Elsevier Limited
Background The effects of pharmacological blood pressure lowering at normal or high-normal blood pressure ranges in people with or without pre-existing cardiovascular disease remains uncertain. We analysed individual participant data from randomised
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b17f611df0472730f0c62968e45810
https://pure.amc.nl/en/publications/pharmacological-blood-pressure-lowering-for-primary-and-secondary-prevention-of-cardiovascular-disease-across-different-levels-of-blood-pressure-an-individual-participantlevel-data-metaanalysis(e47e1f76-6d3d-44ac-a7f7-ea9efe75f18f).html
https://pure.amc.nl/en/publications/pharmacological-blood-pressure-lowering-for-primary-and-secondary-prevention-of-cardiovascular-disease-across-different-levels-of-blood-pressure-an-individual-participantlevel-data-metaanalysis(e47e1f76-6d3d-44ac-a7f7-ea9efe75f18f).html
Autor:
Ikuo Saito, Takao Saruta, Ayano Takeda, Tatsuhiko Azegami, Hiroshi Hirose, Hiroshi Kawabe, Takeshi Kanda
Publikováno v:
Hypertension Research
The Japanese hypertension guidelines report that essential hypertension is detected in 1–3% of upper elementary and high school students during blood pressure (BP) screenings. Hypertension in these age groups is an emerging public health concern ma
Publikováno v:
The Journal of Dermatology. 48
Autor:
Masunori Matsuzaki, Takao Saruta, Toshio Ogihara, Kazuyuki Shimada, Seiji Umemoto, Kazuomi Kario, Masatoshi Kawana, Hiromi Rakugi, Yasuo Ohashi
Publikováno v:
Circulation Journal. 82:457-463
BACKGROUND The Combination Therapy of Hypertension to Prevent Cardiovascular Events (COPE) trial was conducted to compare the effects of regimens combining the dihydropyridine calcium-channel blocker benidipine with each of 3 secondary agent types (a
Publikováno v:
Hypertension Research
We compared three benidipine-based regimens—that is, benidipine plus angiotensin receptor blocker (ARB), β-blocker (BB) or thiazide—and found that the benidipine–BB combination was less beneficial in reducing the risk of stroke than the benidi