Zobrazeno 1 - 10
of 354
pro vyhledávání: '"Takao Hashimoto"'
MYC is a regulator of androgen receptor inhibition-induced metabolic requirements in prostate cancer
Autor:
Preston D. Crowell, Jenna M. Giafaglione, Anthony E. Jones, Nicholas M. Nunley, Takao Hashimoto, Amelie M.L. Delcourt, Anton Petcherski, Raag Agrawal, Matthew J. Bernard, Johnny A. Diaz, Kylie Y. Heering, Rong Rong Huang, Jin-Yih Low, Nedas Matulionis, Nora M. Navone, Huihui Ye, Amina Zoubeidi, Heather R. Christofk, Matthew B. Rettig, Robert E. Reiter, Michael C. Haffner, Paul C. Boutros, Orian S. Shirihai, Ajit S. Divakaruni, Andrew S. Goldstein
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113221- (2023)
Summary: Advanced prostate cancers are treated with therapies targeting the androgen receptor (AR) signaling pathway. While many tumors initially respond to AR inhibition, nearly all develop resistance. It is critical to understand how prostate tumor
Externí odkaz:
https://doaj.org/article/918185a092bc44e997b51df4ec5e68c1
Autor:
Yoshihiro Aoki, Takao Hashimoto
Publikováno v:
Case Reports in Neurology, Vol 14, Iss 1, Pp 197-201 (2022)
We report a case of bilateral ptosis due to paramedian midbrain infarction, which was associated with ipsilateral impaired adduction of the eye and contralateral ataxia. T2-weighted magnetic resonance imaging of the brain revealed a right paramedian
Externí odkaz:
https://doaj.org/article/496b21730b604c53bef751d9957b7106
Autor:
Seira Sato, Sho Ukimoto, Takashi Kanamoto, Nao Sasaki, Takao Hashimoto, Hikaru Saito, Eisuke Hida, Tomoharu Sato, Tatsuo Mae, Ken Nakata
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Although exercise is beneficial for chronic musculoskeletal pain (CMP), the optimal type and amount of exercise are unclear. This study aimed to determine the impact of circuit training that combines aerobic and resistance exercises on adult
Externí odkaz:
https://doaj.org/article/123f23b570b34fd79348faf6df7f61d0
Autor:
Jack Mottahedeh, Michael C. Haffner, Tristan R. Grogan, Takao Hashimoto, Preston D. Crowell, Himisha Beltran, Andrea Sboner, Rohan Bareja, David Esopi, William B. Isaacs, Srinivasan Yegnasubramanian, Matthew B. Rettig, David A. Elashoff, Elizabeth A. Platz, Angelo M. De Marzo, Michael A. Teitell, Andrew S. Goldstein
Publikováno v:
Cancer & Metabolism, Vol 6, Iss 1, Pp 1-17 (2018)
Abstract Background Cancer cell metabolism requires sustained pools of intracellular nicotinamide adenine dinucleotide (NAD+) which is maintained by a balance of NAD+ hydrolase activity and NAD+ salvage activity. We recently reported that human prost
Externí odkaz:
https://doaj.org/article/74edf0c78aa84fd28034f0b9a6de4892
Publikováno v:
Case Reports in Oncology, Vol 11, Iss 2, Pp 577-584 (2018)
Intravascular lymphoma (IVL) is a rare and clinically devastating subtype of extranodal diffuse large B-cell lymphoma with a distinct presentation. Diagnostic difficulty derives from marked variability in clinical presentations and nonspecific labora
Externí odkaz:
https://doaj.org/article/e1a2fdbcbe954424955224aaaa6731c9
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract The production of vertebrate retinal projection neurons, retinal ganglion cells (RGCs), is regulated by cell-intrinsic determinants and cell-to-cell signaling events. The basic-helix-loop-helix (bHLH) protein Atoh7 is a key neurogenic transc
Externí odkaz:
https://doaj.org/article/0e1672e0c3844eaeb4772761d6ff7ebd
Autor:
Radhika Rao Narla, MD, Takao Hashimoto, MD, PhD, Kathleen Kelly, PhD, Anthony Heaney, MD, PhD
Publikováno v:
Journal of Clinical and Translational Endocrinology Case Reports, Vol 2, Iss , Pp 4-6 (2016)
A 52-year old male with a history of insulin treated T2DM complicated by end stage renal disease (ESRD requiring hemodialysis and prior gastric bypass surgery presented with severe recurrent hypoglycemia with seizures. A 72 hour fast demonstrated hyp
Externí odkaz:
https://doaj.org/article/d5d067e5b7154e4984128a3667aad908
Publikováno v:
European Journal of Case Reports in Internal Medicine, Vol 4, Iss 7 (2017)
Objective: To describe hypocalcaemia due to vitamin D deficiency in ‘hikikomori’ syndrome. Materials and methods: A 37-year-old man with ‘hikikomori’ syndrome for a year was admitted with hypocalcaemia (serum ionic calcium 1.17 mmol/l). Seru
Externí odkaz:
https://doaj.org/article/38602d81f3c24062bb346fb7b407b310
Publikováno v:
Case Reports in Neurology, Vol 6, Iss 1, Pp 74-77 (2014)
Isolated bilateral internal ophthalmoplegia is a rare and problematic condition affecting activities of daily living. Herein, we describe the cases of 2 patients with postinfectious isolated bilateral internal ophthalmoplegia, i.e., mydriasis without
Externí odkaz:
https://doaj.org/article/918f245c35d24f8082554bbf2471030b
Publikováno v:
Epilepsy and Behavior Case Reports, Vol 4, Iss C, Pp 30-32 (2015)
We report on a patient with sporadic Creutzfeldt–Jakob disease (CJD) who showed dystonia, periodic myoclonus, and periodic sharp wave complexes (PSWCs) on EEG. The EEG–EMG polygraphic study revealed that dystonia appeared without relation to peri
Externí odkaz:
https://doaj.org/article/297afb64e1fe4ce0a2d64801588523b5