Zobrazeno 1 - 10 of 78 pro vyhledávání: '"Takao FUJIMURA"'
1
Akademický článek
The unique tropism of Mycobacterium leprae to the nasal epithelial cells can be explained by the mammalian cell entry protein 1A.
Autor: Viesta Beby Fadlitha, Fuki Yamamoto, Irfan Idris, Haslindah Dahlan, Naoya Sato, Vienza Beby Aftitah, Andini Febriyanda, Takao Fujimura, Hiroaki Takimoto
Publikováno v: PLoS Neglected Tropical Diseases, Vol 13, Iss 3, p e0006704 (2019)
Leprosy is a chronic infection where the skin and peripheral nervous system is invaded by Mycobacterium leprae. The infection mechanism remains unknown in part because culture methods have not been established yet for M. leprae. Mce1A protein (442 aa
Externí odkaz: https://doaj.org/article/90fc670ede9f44daa1ffc9c2b67f529e
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2
Akademický článek
FK614, a Novel Peroxisome Proliferator-Activated Receptor γ Modulator, Induces Differential Transactivation Through a Unique Ligand-Specific Interaction With Transcriptional Coactivators
Autor: Takao Fujimura, Hiroyuki Sakuma, Satoko Konishi, Tomoya Oe, Naomi Hosogai, Chiaki Kimura, Ichiro Aramori, Seitaro Mutoh
Publikováno v: Journal of Pharmacological Sciences, Vol 99, Iss 4, Pp 342-352 (2005)
Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-dependent transcriptional factor implicated in regulating adipogenesis, glucose homeostasis, and in mediating the action of the insulin sensitizing anti-diabetic thiazolidinedione (TZ
Externí odkaz: https://doaj.org/article/8f701dba02cf4e4a82b7350657759bdc
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3
Akademický článek
Evaluation of Human Peroxisome Proliferator-Activated Receptor (PPAR) Subtype Selectivity of a Variety of Anti-inflammatory Drugs Based on a Novel Assay for PPARδ(β)
Autor: Hitoshi Kojo, Masao Fukagawa, Kaoru Tajima, Akiko Suzuki, Takao Fujimura, Ichiro Aramori, Ken-ichi Hayashi, Shintaro Nishimura
Publikováno v: Journal of Pharmacological Sciences, Vol 93, Iss 3, Pp 347-355 (2003)
ABSTRACT: The nuclear receptor PPAR (peroxisome proliferator-activated receptor) has three subtypes named α, δ(β), and γ that may act as receptors for a range of compounds including antihyperglycaemic drugs, insulin sensitizers, and non-steroidal
Externí odkaz: https://doaj.org/article/143313b742014705beb6f954d5c8a6c8
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5
Invasion of human microvascular endothelial cells by Mycobacterium leprae through Mce1A protein
Autor: Vienza Beby Aftitah, Ahmad Haykal Abdurrahman, Viesta Beby Fadlitha, Naoya Sato, Fatulrachman, Irfan Idris, Takao Fujimura, Hiroaki Takimoto
Publikováno v: Dermatologic Therapy
In patients with lepromatous leprosy, Mycobacterium leprae is often observed inside the human microvascular endothelial cells (HMVEC) surrounding Schwann cells (SC) at the site of lesions in the peripheral nerves. Based on this observation, it is con
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793df56c7cb5003ce88d63fc32682657
https://pubmed.ncbi.nlm.nih.gov/32441403
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6
The unique tropism of Mycobacterium leprae to the nasal epithelial cells can be explained by the mammalian cell entry protein 1A
Autor: Naoya Sato, Andini Febriyanda, Hiroaki Takimoto, Irfan Idris, Vienza Beby Aftitah, Viesta Beby Fadlitha, Takao Fujimura, Haslindah Dahlan, Fuki Yamamoto
Publikováno v: PLoS Neglected Tropical Diseases, Vol 13, Iss 3, p e0006704 (2019)
PLoS Neglected Tropical Diseases
Leprosy is a chronic infection where the skin and peripheral nervous system is invaded by Mycobacterium leprae. The infection mechanism remains unknown in part because culture methods have not been established yet for M. leprae. Mce1A protein (442 aa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f604d073ec5e0893b5723eb2b047d5
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8
Hes1 regulates the number and anterior–posterior patterning of mesencephalic dopaminergic neurons at the mid/hindbrain boundary (isthmus)
Autor: Takayoshi Saitoh, Yoko Kameda, Takao Fujimura
Publikováno v: Developmental Biology. 358:91-101
The lack of the Hes1 gene leads to the failure of cranial neurulation due to the premature onset of neural differentiation. Hes1 homozygous null mutant mice displayed a neural tube closure defect, and exencephaly was induced at the mid/hindbrain boun
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d078049a3b44a41788af8c7047ccfbdd
https://doi.org/10.1016/j.ydbio.2011.07.016
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9
History for animal model of Hansen's disease and characteristic of leprosy in hypertensive nude rat
Autor: Koichi Suzuki, Yasuko Yogi, Takao Fujimura
Publikováno v: Japanese journal of leprosy. 77:197-204
The long search of an animal model for leprosy were carried out as many researchers since the Mycobacterium leprae discovery by Dr. Hansen in 1874. The remarkable results were left after the development of the foot-pad method by Dr. Shepard in 1960.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2208403572a3dc0a19694ac668df2177
https://doi.org/10.5025/hansen.77.197
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10
Recombinant Mycobacterium leprae protein associated with entry into mammalian cells of respiratory and skin components
Autor: Masanori Matsuoka, Maho Kanoh, Yasuko Yogi, Takao Fujimura, Naoya Sato, Lee W. Riley, Mikio Masuzawa, Kensei Katsuoka
Publikováno v: Journal of Dermatological Science. 46:101-110
The transmission of Mycobacterium leprae, the causative pathogen of leprosy, has been postulated to occur mainly through upper respiratory route rather than skin-to-skin contact via minor injuries. The M. leprae genome contains mce1A gene, which enco
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b519ff9421d5ed2d9aa81b5250fd1f
https://doi.org/10.1016/j.jdermsci.2007.01.006
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