Zobrazeno 1 - 10
of 917
pro vyhledávání: '"Takao, Watanabe"'
Autor:
Yusuke Okujima, Takao Watanabe, Takeshi Ito, Yasumichi Inoue, Yutaka Kasai, Yusuke Imai, Yoshiko Nakamura, Mitsuhito Koizumi, Osamu Yoshida, Yoshio Tokumoto, Masashi Hirooka, Masanori Abe, Ryosuke Kawakami, Takashi Saitou, Takeshi Imamura, Yoshinori Murakami, Yoichi Hiasa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract RNA-dependent protein kinase (PKR) may have a positive regulatory role in controlling tumor growth and progression in hepatocellular carcinoma (HCC). However, the downstream substrates and the molecular mechanism of PKR in the growth and pro
Externí odkaz:
https://doaj.org/article/dd42980cfe6a449483d6c8e426e3ad7c
Autor:
Teruki Miyake, Shinya Furukawa, Bunzo Matsuura, Osamu Yoshida, Masumi Miyazaki, Akihito Shiomi, Ayumi Kanamoto, Hironobu Nakaguchi, Yoshiko Nakamura, Yusuke Imai, Mitsuhito Koizumi, Takao Watanabe, Yasunori Yamamoto, Yohei Koizumi, Yoshio Tokumoto, Masashi Hirooka, Teru Kumagi, Eiji Takesita, Yoshio Ikeda, Masanori Abe, Yoichi Hiasa
Publikováno v:
Diabetes & Metabolism Journal, Vol 48, Iss 3, Pp 440-448 (2024)
Background Poor lifestyle habits may worsen nonalcoholic fatty liver disease (NAFLD), with progression to nonalcoholic steatohepatitis (NASH) and cirrhosis. This study investigated the association between glycemic control status and hepatic histologi
Externí odkaz:
https://doaj.org/article/0799ea71104b4e77bcf45e6604848a54
Autor:
Yu Hashimoto, Yoshio Tokumoto, Takao Watanabe, Yusuke Ogi, Hiroki Sugishita, Satoshi Akita, Kazuki Niida, Mirai Hayashi, Masaya Okada, Kana Shiraishi, Kazuhiro Tange, Hideomi Tomida, Yasunori Yamamoto, Eiji Takeshita, Yoshio Ikeda, Taro Oshikiri, Yoichi Hiasa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Double-stranded RNA-activated protein kinase R (PKR) is highly expressed in colorectal cancer (CRC). However, the role of PKR in CRC remains unclear. The aim of this study was to clarify whether C16 (a PKR inhibitor) exhibits antitumor effec
Externí odkaz:
https://doaj.org/article/e06ff7febde044f0ac638efddc24847e
Autor:
Tetsuhiro Tsujino, Tomoni Kasahara, Hideo Kawabata, Taisuke Watanabe, Koji Nishiyama, Yutaka Kitamura, Takao Watanabe, Hajime Okudera, Tomoharu Mochizuki, Takashi Ushiki, Tomoyuki Kawase
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
Backgroundfluoride is a beneficial ion that has been used in various fields, from industrial products to therapeutics. However, due to its narrow therapeutic index, fluoride sometimes acts as a toxic agent at relatively higher concentrations in the h
Externí odkaz:
https://doaj.org/article/0ccb239ef76b4dc980f6f832e19ff3df
Autor:
Hanako Nozu, Haruka Tamura, Takemi Kudo, Tomoko Araki, Hidetaka Sato, Takao Watanabe, Isoji Sasagawa
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301676 (2024)
IntroductionThe number of patients with chronic kidney disease is increasing worldwide; previous studies have suggested that advanced practice nurses, including nurse practitioners and clinical nurse specialists, with expert practice skills can provi
Externí odkaz:
https://doaj.org/article/b4c31dfe40144a7e86b5506ef13f42ea
Autor:
Takao Watanabe, Yoshio Tokumoto, Kouji Joko, Kojiro Michitaka, Norio Horiike, Yoshinori Tanaka, Atsushi Hiraoka, Fujimasa Tada, Hironori Ochi, Yoshiyasu Kisaka, Seiji Nakanishi, Sen Yagi, Kazuhiko Yamauchi, Makoto Higashino, Kana Hirooka, Makoto Morita, Yuki Okazaki, Atsushi Yukimoto, Masashi Hirooka, Masanori Abe, Yoichi Hiasa
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The time point of the most precise predictor of hepatocellular carcinoma (HCC) development after viral eradication with direct-acting antiviral (DAA) therapy is unclear. In this study we developed a scoring system that can accurately predict
Externí odkaz:
https://doaj.org/article/02e928ce943d4b889b09d5ae76d10745
Autor:
Masashi Hirooka, Yohei Koizumi, Ryo Yano, Yoshiko Nakamura, Koutarou Sunago, Atsushi Yukimoto, Takao Watanabe, Osamu Yoshida, Yoshio Tokumoto, Masanori Abe, Yoichi Hiasa
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract For patients with cirrhosis, no definitive predictor of the efficacy and prognosis of tolvaptan treatment exists. We assessed the cisterna chyli’s utility as an optimal marker. We retrospectively enrolled 172 patients with cirrhosis. The e
Externí odkaz:
https://doaj.org/article/15304c9f38ce487fb49de95aaf7bf265
Autor:
Setsuko Tajima, Yuhta Itoh, Katsuya Mizutamari, Shigeki Miyasaka, Masamichi Nakajima, Nae Sasaki, Shunpei Yamaguchi, Kei-ichi Harada, Takao Watanabe
Publikováno v:
Journal of the Physical Society of Japan; 10/15/2024, Vol. 93 Issue 10, p103701-1-103701-5, 5p
Autor:
Masayuki Nakamura, Hideo Masuki, Hideo Kawabata, Taisuke Watanabe, Takao Watanabe, Tetsuhiro Tsujino, Kazushige Isobe, Yutaka Kitamura, Carlos Fernando Mourão, Tomoyuki Kawase
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 2871 (2023)
Plasma gel (PG) is a blood-derived biomaterial that can be prepared by heating or chemical cross-linking without the aid of intrinsic coagulation activity and has gradually been applied in the field of esthetic surgery. To explore the applicability o
Externí odkaz:
https://doaj.org/article/8079e0947093433ab721521532606718
Autor:
Mitsuhito Koizumi, Takao Watanabe, Junya Masumoto, Kotaro Sunago, Yoshiki Imamura, Kozue Kanemitsu, Teru Kumagi, Yoichi Hiasa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) is a key adaptor protein of inflammasomes and a proapoptotic molecule; however, its roles in signal transduction in pancreatic ductal adenocarcinoma (PDAC)
Externí odkaz:
https://doaj.org/article/5de6331f96c94fc9b968a3ea05391b44