Zobrazeno 1 - 10
of 221
pro vyhledávání: '"Takanori Ohnishi"'
Autor:
Takanori Ohnishi
Publikováno v:
Brain Sciences, Vol 14, Iss 4, p 309 (2024)
Glioblastoma (GBM) is the most malignant brain tumor in adults and shows an extremely poor prognosis, with a median survival of 15 months [...]
Externí odkaz:
https://doaj.org/article/b12bb4002cfc4b55a932a7c5d7ddf17a
Autor:
Akihiro Inoue, Takanori Ohnishi, Masahiro Nishikawa, Hideaki Watanabe, Kosuke Kusakabe, Mashio Taniwaki, Hajime Yano, Yoshihiro Ohtsuka, Shirabe Matsumoto, Satoshi Suehiro, Daisuke Yamashita, Seiji Shigekawa, Hisaaki Takahashi, Riko Kitazawa, Junya Tanaka, Takeharu Kunieda
Publikováno v:
Biomedicines, Vol 11, Iss 9, p 2369 (2023)
Recurrent glioblastoma multiforme (GBM) is largely attributed to peritumoral infiltration of tumor cells. As higher CD44 expression in the tumor periphery correlates with higher risk of GBM invasion, the present study analyzed the relationship betwee
Externí odkaz:
https://doaj.org/article/44706f2a476847e3abcc2f9a4dfed5f5
Autor:
Masahiro Nishikawa, Akihiro Inoue, Takanori Ohnishi, Hajime Yano, Yonehiro Kanemura, Shohei Kohno, Shiro Ohue, Saya Ozaki, Shirabe Matsumoto, Satoshi Suehiro, Yawara Nakamura, Seiji Shigekawa, Hideaki Watanabe, Riko Kitazawa, Junya Tanaka, Takeharu Kunieda
Publikováno v:
Cancer Medicine, Vol 10, Iss 6, Pp 2013-2025 (2021)
Abstract Antiangiogenic therapy with bevacizumab (Bev), a monoclonal antibody targeting vascular endothelial growth factor (VEGF), is a common treatment for recurrent glioblastoma (GBM), but its survival benefit is limited. Resistance to Bev is thoug
Externí odkaz:
https://doaj.org/article/c9c9b0ba3246479ab1c5326b3e7cd505
Autor:
Masahiro Nishikawa, Akihiro Inoue, Takanori Ohnishi, Hajime Yano, Saya Ozaki, Yonehiro Kanemura, Satoshi Suehiro, Yoshihiro Ohtsuka, Shohei Kohno, Shiro Ohue, Seiji Shigekawa, Hideaki Watanabe, Riko Kitazawa, Junya Tanaka, Takeharu Kunieda
Publikováno v:
Translational Oncology, Vol 14, Iss 8, Pp 101137- (2021)
The poor prognosis of glioblastoma multiforme (GBM) is primarily due to highly invasive glioma stem-like cells (GSCs) in tumors. Upon GBM recurrence, GSCs with highly invasive and highly migratory activities must assume a less-motile state and prolif
Externí odkaz:
https://doaj.org/article/33c4ef903c5b4700aee894ff74b59436
Autor:
Takanori Ohnishi, Daisuke Yamashita, Akihiro Inoue, Satoshi Suehiro, Shiro Ohue, Takeharu Kunieda
Publikováno v:
Brain Sciences, Vol 12, Iss 5, p 567 (2022)
The effectiveness of carmustine (BCNU) wafers on local recurrence of glioblastoma (GBM) remains contentious. We investigated the accumulating high-dose effects of BCNU released from the wafers on the survival of GBM patients by measuring BCNU concent
Externí odkaz:
https://doaj.org/article/75a5ab9347ad40bf91c4fbf6aabafd3c
Autor:
Kana Kobayashi, Hajime Yano, Akihiro Umakoshi, Shirabe Matsumoto, Ayano Mise, Yu Funahashi, Yoshitomo Ueno, Yoshiaki Kamei, Yasutsugu Takada, Yoshiaki Kumon, Takanori Ohnishi, Junya Tanaka
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 18, Iss 4, Pp 229-241 (2016)
CD200 induces immunosuppression in myeloid cells expressing its receptor CD200R, which may have consequences for tumor immunity. We found that human carcinoma tissues express not only full-length CD200 (CD200L) but also its truncated form, CD200S. Al
Externí odkaz:
https://doaj.org/article/2fb2b57060e14c03bd6ec087d39e44c7
Autor:
Masahiro Nishikawa, Akihiro Inoue, Takanori Ohnishi, Shohei Kohno, Shiro Ohue, Shirabe Matsumoto, Satoshi Suehiro, Daisuke Yamashita, Saya Ozaki, Hideaki Watanabe, Hajime Yano, Hisaaki Takahashi, Riko Kitazawa, Junya Tanaka, Takeharu Kunieda
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Glioblastoma multiforme (GBM) is the most aggressive malignant brain tumor and a subpopulation of glioma stem-like cells (GSCs) is likely responsible for the invariable recurrence following maximum resection and chemoradiotherapy. As most GSCs that a
Externí odkaz:
https://doaj.org/article/c69f9090d9b744a8851530dcc4ac70b6
Autor:
Akihiro Inoue, Takanori Ohnishi, Shohei Kohno, Naoya Nishida, Yawara Nakamura, Yoshihiro Ohtsuka, Shirabe Matsumoto, Shiro Ohue
Publikováno v:
International Journal of Endocrinology, Vol 2015 (2015)
Purpose. We investigate the usefulness of multimodal assistant systems using a fusion model of preoperative three-dimensional (3D) computed tomography (CT) and magnetic resonance imaging (MRI) along with endoscopy with indocyanine green (ICG) fluores
Externí odkaz:
https://doaj.org/article/b966f34687464b34a14a391cb466a6c1
Publikováno v:
Cell Transplantation, Vol 4 (1995)
The purpose of this study was to assess whether xenogeneic tumor cells secreting β-endorphin and immunologically isolated in polymer capsules could survive and continue to reduce pain when transplanted into the spinal cerebro-spinal fluid (CSF) spac
Externí odkaz:
https://doaj.org/article/b8c6e14b45d44f47925cee88e043ba5f
Autor:
Yoshihiro Ohtsuka, Satoshi Suehiro, Akihiro Inoue, Takanori Ohnishi, Masahiro Nishikawa, Daisuke Yamashita, Hajime Yano, Choudhury, Mohammed E., Saya Ozaki, Sampetrean, Oltea, Hideyuki Saya, Hideaki Watanabe, Junya Tanaka, Takeharu Kunieda
Publikováno v:
Journal of Neurosurgery; Sep2024, Vol. 141 Issue 3, p653-663, 11p