Zobrazeno 1 - 10 of 321 pro vyhledávání: '"Takanori Ohnishi"'
2
Akademický článek
Current Status and Future Perspective in Glioma Invasion Research
Autor: Takanori Ohnishi
Publikováno v: Brain Sciences, Vol 14, Iss 4, p 309 (2024)
Glioblastoma (GBM) is the most malignant brain tumor in adults and shows an extremely poor prognosis, with a median survival of 15 months [...]
Externí odkaz: https://doaj.org/article/b12bb4002cfc4b55a932a7c5d7ddf17a
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3
Akademický článek
Identification of CD44 as a Reliable Biomarker for Glioblastoma Invasion: Based on Magnetic Resonance Imaging and Spectroscopic Analysis of 5-Aminolevulinic Acid Fluorescence
Autor: Akihiro Inoue, Takanori Ohnishi, Masahiro Nishikawa, Hideaki Watanabe, Kosuke Kusakabe, Mashio Taniwaki, Hajime Yano, Yoshihiro Ohtsuka, Shirabe Matsumoto, Satoshi Suehiro, Daisuke Yamashita, Seiji Shigekawa, Hisaaki Takahashi, Riko Kitazawa, Junya Tanaka, Takeharu Kunieda
Publikováno v: Biomedicines, Vol 11, Iss 9, p 2369 (2023)
Recurrent glioblastoma multiforme (GBM) is largely attributed to peritumoral infiltration of tumor cells. As higher CD44 expression in the tumor periphery correlates with higher risk of GBM invasion, the present study analyzed the relationship betwee
Externí odkaz: https://doaj.org/article/44706f2a476847e3abcc2f9a4dfed5f5
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4
Akademický článek
CD44 expression in the tumor periphery predicts the responsiveness to bevacizumab in the treatment of recurrent glioblastoma
Autor: Masahiro Nishikawa, Akihiro Inoue, Takanori Ohnishi, Hajime Yano, Yonehiro Kanemura, Shohei Kohno, Shiro Ohue, Saya Ozaki, Shirabe Matsumoto, Satoshi Suehiro, Yawara Nakamura, Seiji Shigekawa, Hideaki Watanabe, Riko Kitazawa, Junya Tanaka, Takeharu Kunieda
Publikováno v: Cancer Medicine, Vol 10, Iss 6, Pp 2013-2025 (2021)
Abstract Antiangiogenic therapy with bevacizumab (Bev), a monoclonal antibody targeting vascular endothelial growth factor (VEGF), is a common treatment for recurrent glioblastoma (GBM), but its survival benefit is limited. Resistance to Bev is thoug
Externí odkaz: https://doaj.org/article/c9c9b0ba3246479ab1c5326b3e7cd505
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5
Akademický článek
Hypoxia-induced phenotypic transition from highly invasive to less invasive tumors in glioma stem-like cells: Significance of CD44 and osteopontin as therapeutic targets in glioblastoma
Autor: Masahiro Nishikawa, Akihiro Inoue, Takanori Ohnishi, Hajime Yano, Saya Ozaki, Yonehiro Kanemura, Satoshi Suehiro, Yoshihiro Ohtsuka, Shohei Kohno, Shiro Ohue, Seiji Shigekawa, Hideaki Watanabe, Riko Kitazawa, Junya Tanaka, Takeharu Kunieda
Publikováno v: Translational Oncology, Vol 14, Iss 8, Pp 101137- (2021)
The poor prognosis of glioblastoma multiforme (GBM) is primarily due to highly invasive glioma stem-like cells (GSCs) in tumors. Upon GBM recurrence, GSCs with highly invasive and highly migratory activities must assume a less-motile state and prolif
Externí odkaz: https://doaj.org/article/33c4ef903c5b4700aee894ff74b59436
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7
Akademický článek
Is Interstitial Chemotherapy with Carmustine (BCNU) Wafers Effective against Local Recurrence of Glioblastoma? A Pharmacokinetic Study by Measurement of BCNU in the Tumor Resection Cavity
Autor: Takanori Ohnishi, Daisuke Yamashita, Akihiro Inoue, Satoshi Suehiro, Shiro Ohue, Takeharu Kunieda
Publikováno v: Brain Sciences, Vol 12, Iss 5, p 567 (2022)
The effectiveness of carmustine (BCNU) wafers on local recurrence of glioblastoma (GBM) remains contentious. We investigated the accumulating high-dose effects of BCNU released from the wafers on the survival of GBM patients by measuring BCNU concent
Externí odkaz: https://doaj.org/article/75a5ab9347ad40bf91c4fbf6aabafd3c
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