Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Takanori Kumano"'
Autor:
Tohru Ibi, Masaru Kuriyama, Takeshi Azuma, Akihiro Fujii, Koji Hayashi, Masahiro Ohtani, Makoto Yoneda, Ko Sahashi, Atsushi Muramatsu, H. Nakagawa, Takanori Kumano, Satoru Takabatake
Publikováno v:
Internal Medicine. 43:1126-1130
Objective We analyzed the accumulation of a mitochondrial A-to-G mutation at nucleotide position 3243 (A3243G) in the stomach and gastric motility in patients with gastric symptoms, post-prandial nausea/vomiting and epigastralgia. Methods Detection a
Publikováno v:
FEBS Letters. 508:53-56
Previous studies from this laboratory have shown that 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (HCRI) causes apoptotic cell death of a muscle cell-derived cell line, L6 myoblasts, by involving the phosphatidylinositol-3 (PI-3) kinase
Autor:
Tadanori Hamano, Yasutaka Kawamura, Takanori Kumano, Jiro Fujiyama, Masaru Kuriyama, Mikio Hirayama, Tatsuro Mutoh, Keita Ito, T. Inagaki
Publikováno v:
Journal of the neurological sciences. 199(1-2)
We report here the muscle MRI findings in two patients with human T-cell lymphotropic virus type I-associated myelopathy (HAM). It is known that thigh muscles are vulnerable in HAM patients, but detailed information about the affected muscles has not
Autor:
Yasutaka Kawamura, Tadanori Hamano, Masaru Kuriyama, Tatsuro Mutoh, Tetsuya Kimura, Takanori Kumano, Mikio Hirayama
Publikováno v:
European neurology. 46(3)
Publikováno v:
Brain research. 859(1)
The present study was aimed at investigating the possible toxicity of simvastatin on a neuronal cell line, PC12 cells. Simvastatin clearly induced a transient morphological differentiation as evidenced by the occurrence of neurite outgrowth with a tr
Publikováno v:
FEBS letters. 446(1)
Our previous studies have shown that the HMG-CoA reductase (HCR) inhibitor (HCRI), simvastatin, kills L6 myoblasts by involving Ca2+ mobilization from the Ca2+ pool in the cells but not by influx from extracellular space. More recently, we found that
Publikováno v:
FEBS letters. 444(1)
Our previous studies have shown that the HMG-CoA reductase (HCR) inhibitor (HCRI), simvastatin, causes myopathy in rabbits and kills L6 myoblasts. The present study was designed to elucidate the molecular mechanism of HCRI-induced cell death. We have
Publikováno v:
FEBS letters. 438(3)
Our previous studies have shown that the HMG-CoA reductase inhibitor (HCRI) causes rhabdomyolysis and electrical myotonia in rabbits and also kills L6 myoblasts in culture. In the present study, we analyzed the intracellular signal transduction pathw
Autor:
Tadanori Hamano, Masaru Kuriyama, Takanori Kumano, Takashi Aita, Tatsuro Mutoh, Mikio Hirayama, Masayuki Shiratori
Publikováno v:
Journal of the neurological sciences. 151(1)
A patient with chorea-acanthocytosis presenting with axonal neuropathy showed an elevation in IgM polyclonal antibodies to the GM1 ganglioside, which were estimated by enzyme-linked immunosorbent assay and complement-mediated liposome immune lysis as
Publikováno v:
Internal medicine (Tokyo, Japan). 34(2)
Cerebral ischemia has been proposed as the etiology of transient global amnesia. Recently, however, migranous and epileptic etiologies have attracted attention. A 56-year-old man had transient global amnesia and the next day began to display symptoms