Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Takanori Ohgaru"'
Autor:
Etuko Uejima, Shigeki Inui, Junichi Takahara, Kousuke Okamoto, Yu-Shi Tian, Teruo Yasunaga, Norihito Kawashita, Takanori Ohgaru, Yuko Shirakuni, Hiroyuki Yamasaki, Tatsuya Takagi, Ran Inoue
Publikováno v:
Therapeutic Innovation & Regulatory Science. 47:235-241
This study aimed to determine the potentially severe chemical properties of drugs that can cause adverse drug reactions (ADRs) such as erythema multiforme (EM), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) by using a data mini
Autor:
Hironori Kuga, Andreia V. Faria, David J. Schretlen, Lindsay S. Shaffer, Jeffrey L. Crawford, Akira Sawa, Takanori Ohgaru, Susumu Mori
Publikováno v:
Biological Psychiatry. 83:S329
Autor:
Rika Nishikiori, Tatsuya Takagi, Yuko Shirakuni, Ryo Shimizu, Kousuke Okamoto, Masaya Kawase, Takanori Ohgaru
Publikováno v:
Journal of Chemical Information and Modeling. 48:207-212
Comparative Molecular Field Analysis (CoMFA) is most widely used as one of the 3-dimensional QSAR (3D-QSAR) methods to identify the relationship between chemical structure and biological activity. Conventional CoMFA requires at least 3 orders of expe
Publikováno v:
SLAS Discovery. 7:89-94
The Twister &! RapidPlate Integrated System by TANabe, or TRISTAN, consists of a 96-channel dispenser (Rapid-Plate 96), a plate reader (V-MAX), and a simple robot arm (Twister). We developed TRISTAN for effectively conducting a homogeneous assay. Alt
Publikováno v:
Journal of Electroanalytical Chemistry. 496:37-43
An approximate equation is derived for the steady-state limiting current of mediated bioelectrocatalysis as a function of the bulk mediator concentration in the case where enzyme and mediator are in the soluble state and the substrate concentration i
Autor:
Hideaki Kinoshita, Tokuji Ikeda, Keiko Yamamoto, Masaki Torimura, Kenji Kano, Takanori Ohgaru
Publikováno v:
Analytica Chimica Acta. 406:201-207
A flow injection system for determination of hydrogen peroxide was constructed using a peroxidase/ferrocene-embedded carbon paste (POD-Fc-CP) electrode covered with a membrane. H2O2 was reduced bioelectrocatalytically at 100 mV (versus Ag/AgCl/sat. K
Autor:
Ryo Shimizu, Takanori Ohgaru, Kousuke Okamoto, Rika Nishikiori, Tatsuya Takagi, Masaya Kawase, Yuko Shirakuni, Norihito Kawashita
Publikováno v:
ChemInform. 39
Conventional comparative molecular field analysis (CoMFA) requires at least 3 orders of experimental data, such as IC50 and Ki, to obtain a good model, although practically there are many screening assays where biological activity is measured only by
Autor:
Tatsuya Takagi, Takanori Ohgaru, Ryo Shimizu, Masaya Kawase, Kousuke Okamoto, Norihito Kawashita, Yuko Shirakuni, Rika Nishikiori
Publikováno v:
Journal of chemical information and modeling. 48(4)
Conventional comparative molecular field analysis (CoMFA) requires at least 3 orders of experimental data, such as IC 50 and K i, to obtain a good model, although practically there are many screening assays where biological activity is measured only
Publikováno v:
European journal of biochemistry. 268(16)
We have isolated and characterized rat cyclic nucleotide phosphodiesterase (PDE)11A, which exhibits properties of a dual-substrate PDE, and its splice variants (RNPDE11A2, RNPDE11A3, and RNPDE11A4). The deduced amino-acid sequence of the longest form
Publikováno v:
Chemistry Letters. 25:439-440
Approximate and more precise empirical equations have been derived for the steady state limiting currents of bioelectrocatalysis based on homogeneous enzyme and mediator at sufficiently high concentrations of the substrate. These equations allow us t