Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Takanori, Onouchi"'
Autor:
Atsuko Sugimoto, Takahiro Watanabe, Kazuhiro Matsuoka, Yusuke Okuno, Yusuke Yanagi, Yohei Narita, Seiyo Mabuchi, Hiroyuki Nobusue, Eiji Sugihara, Masaya Hirayama, Tomihiko Ide, Takanori Onouchi, Yoshitaka Sato, Teru Kanda, Hideyuki Saya, Yasumasa Iwatani, Hiroshi Kimura, Takayuki Murata
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT The in vitro growth transformation of primary B cells by Epstein-Barr virus (EBV) is the initial step in the development of posttransplant lymphoproliferative disorder (PTLD). We performed electron microscopic analysis and immunostaining of
Externí odkaz:
https://doaj.org/article/efb562a677cd4a019fb90202ef91cf84
Autor:
Hiroshi Ageta, Natsumi Ageta-Ishihara, Keisuke Hitachi, Ozge Karayel, Takanori Onouchi, Hisateru Yamaguchi, Tomoaki Kahyo, Ken Hatanaka, Koji Ikegami, Yusuke Yoshioka, Kenji Nakamura, Nobuyoshi Kosaka, Masashi Nakatani, Akiyoshi Uezumi, Tomihiko Ide, Yutaka Tsutsumi, Haruhiko Sugimura, Makoto Kinoshita, Takahiro Ochiya, Matthias Mann, Mitsutoshi Setou, Kunihiro Tsuchida
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Exosomes mediate cell-to-cell communication by transporting proteins, mRNAs, and miRNAs but the mechanisms of protein sorting to exosomes are poorly understood. Here, the authors uncover that ubiquitin-like 3 (UBL3) regulates protein sorting to exoso
Externí odkaz:
https://doaj.org/article/c92e3a81f2284cbda20dffe286df8d8c
Autor:
Kazuo Takahashi, Takanori Onouchi, Masaya Hirayama, Masato Abe, Yoshimitsu Katoh, Kazuya Shiogama
Publikováno v:
Microscopy. 71:87-92
Huntingtin-associated protein 1 (HAP1) is abundantly expressed in the neurons of the central nervous system and forms unique intracytoplasmic inclusions of unknown function called ‘stigmoid bodies’ (STBs). Transmission electron microscopy has rev
Autor:
Chenguang Li, Takao Senda, Kazuyoshi Sakai, Takanori Onouchi, Shuji Matsuda, Masaya Hirayama, Nami Yamada
Publikováno v:
Medical Molecular Morphology. 54:31-40
In the present study, we examined morphology and function of hippocampus in the APC1638T/1638T mouse. Expression levels of the APC mRNA and protein were both identical in the hippocampus of the APC+/+ and APC1638T/1638T mice. The dentate gyrus of the
Autor:
Masaya Hirayama, Masashi Kondo, Takanori Onouchi, Sumito Isogai, Naoki Yamamoto, Kazuyoshi Imaizumi, Noriko Hiramatsu, Shingo Maeda, Takuma Ina
Publikováno v:
Medical Molecular Morphology. 53:63-72
Dendritic cell-based immunotherapy, which uses a patient's own immune cells, can be used for cancer treatment and allergy control, such as autoimmune disease and rejection associated with transplantation. However, these treatments create a burden on
Autor:
Takanori Onouchi, Daisuke Hasegawa, Naohide Kuriyama, Osamu Nishida, Tomoyuki Nakamura, Yu Kato, Takahiro Kawaji, Yasuyo Shimomura
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 4933, p 4933 (2021)
Volume 22
Issue 9
International Journal of Molecular Sciences, Vol 22, Iss 4933, p 4933 (2021)
Volume 22
Issue 9
Neutrophil extracellular trap (NET) formation, an innate immune system response, is associated with thrombogenesis and vascular endothelial injury. Circulatory disorders due to microvascular thrombogenesis are one of the principal causes of organ dam
Autor:
Kazuya Shiogama, Ken-ichi Inada, Michinori Kohara, Hidemi Teramoto, Yasuyoshi Mizutani, Takanori Onouchi, Yutaka Tsutsumi
Publikováno v:
International Journal of Hepatology, Vol 2013 (2013)
Background. In situ hybridization (ISH) with high sensitivity has been requested to demonstrate hepatitis C virus (HCV) RNA in formalin-fixed, paraffin-embedded (FFPE) sections of the liver. Methods. ISH employing a locked-nucleic-acid- (LNA-)modifie
Externí odkaz:
https://doaj.org/article/9f4cd1a0837d4b888eeb89deb04d844a
Autor:
Mitsutoshi Setou, Koji Ikegami, Tomoaki Kahyo, Akiyoshi Uezumi, Makoto Kinoshita, Kenji Nakamura, Hisateru Yamaguchi, Nobuyoshi Kosaka, Kunihiro Tsuchida, Ozge Karayel, Haruhiko Sugimura, Hiroshi Ageta, Tomihiko Ide, Yutaka Tsutsumi, Takanori Onouchi, Masashi Nakatani, Yusuke Yoshioka, Ken Hatanaka, Takahiro Ochiya, Keisuke Hitachi, Natsumi Ageta-Ishihara, Matthias Mann
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications
Nature Communications
Exosomes, a type of small extracellular vesicles (sEVs), derived from multivesicular bodies (MVBs), mediate cell-to-cell communication by transporting proteins, mRNAs, and miRNAs. However, the molecular mechanism by which proteins are sorted to sEVs
Publikováno v:
Medical Molecular Morphology. 50:94-102
The adenomatous polyposis coli (APC) is a multifunctional protein as well as a tumor suppressor. To determine the functions of the C-terminal domain of APC, we explored APC 1638T/1638T (APC1638T) mice that express a truncated APC lacking the C-termin
Publikováno v:
Acta Histochemica et Cytochemica
Neutrophil extracellular traps (NETs) released from dead neutrophils at the site of inflammation represent webs of neutrophilic DNA stretches dotted with granule-derived antimicrobial proteins, including lactoferrin, and play important roles in innat