Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Takanori, Nakane"'
Autor:
Basudev Maity, Mitsuo Shoji, Fangjia Luo, Takanori Nakane, Satoshi Abe, Shigeki Owada, Jungmin Kang, Kensuke Tono, Rie Tanaka, Thuc Toan Pham, Mariko Kojima, Yuki Hishikawa, Junko Tanaka, Jiaxin Tian, Misaki Nagama, Taiga Suzuki, Hiroki Noya, Yuto Nakasuji, Asuka Asanuma, Xinchen Yao, So Iwata, Yasuteru Shigeta, Eriko Nango, Takafumi Ueno
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Determining short-lived intermediate structures in chemical reactions is challenging. Although ultrafast spectroscopic methods can detect the formation of transient intermediates, real-space structures cannot be determined directly from such
Externí odkaz:
https://doaj.org/article/3cfd85e7dc894b0b8e4ff072dfe8dad1
Autor:
Dongqing Pan, Ryo Oyama, Tomomi Sato, Takanori Nakane, Ryo Mizunuma, Keita Matsuoka, Yasumasa Joti, Kensuke Tono, Eriko Nango, So Iwata, Toru Nakatsu, Hiroaki Kato
Publikováno v:
IUCrJ, Vol 9, Iss 1, Pp 134-145 (2022)
CmABCB1 is a Cyanidioschyzon merolae homolog of human ABCB1, a well known ATP-binding cassette (ABC) transporter responsible for multi-drug resistance in various cancers. Three-dimensional structures of ABCB1 homologs have revealed the snapshots of i
Externí odkaz:
https://doaj.org/article/46bdada9d6934983b448a8f4996580df
Autor:
Hongjie Li, Yoshiki Nakajima, Takashi Nomura, Michihiro Sugahara, Shinichiro Yonekura, Siu Kit Chan, Takanori Nakane, Takahiro Yamane, Yasufumi Umena, Mamoru Suzuki, Tetsuya Masuda, Taiki Motomura, Hisashi Naitow, Yoshinori Matsuura, Tetsunari Kimura, Kensuke Tono, Shigeki Owada, Yasumasa Joti, Rie Tanaka, Eriko Nango, Fusamichi Akita, Minoru Kubo, So Iwata, Jian-Ren Shen, Michihiro Suga
Publikováno v:
IUCrJ, Vol 8, Iss 3, Pp 431-443 (2021)
Photosystem II (PSII) catalyzes light-induced water oxidation through an Si-state cycle, leading to the generation of di-oxygen, protons and electrons. Pump–probe time-resolved serial femtosecond crystallography (TR-SFX) has been used to capture st
Externí odkaz:
https://doaj.org/article/35188f25a618474b8a4bc94e01f925d7
Autor:
Dari Kimanius, Gustav Zickert, Takanori Nakane, Jonas Adler, Sebastian Lunz, Carola-Bibiane Schönlieb, Ozan Öktem, Sjors H. W. Scheres
Publikováno v:
IUCrJ, Vol 8, Iss 1, Pp 60-75 (2021)
Three-dimensional reconstruction of the electron-scattering potential of biological macromolecules from electron cryo-microscopy (cryo-EM) projection images is an ill-posed problem. The most popular cryo-EM software solutions to date rely on a regula
Externí odkaz:
https://doaj.org/article/d604d0022e5240f482493f2f774c2a12
Autor:
Dohyun Im, Asuka Inoue, Takaaki Fujiwara, Takanori Nakane, Yasuaki Yamanaka, Tomoko Uemura, Chihiro Mori, Yuki Shiimura, Kanako Terakado Kimura, Hidetsugu Asada, Norimichi Nomura, Tomoyuki Tanaka, Ayumi Yamashita, Eriko Nango, Kensuke Tono, Francois Marie Ngako Kadji, Junken Aoki, So Iwata, Tatsuro Shimamura
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
The dopamine D2 receptor (D2R) is a GPCR and an important drug target for schizophrenia treatment. Here, the authors present the crystal structure of human D2R in complex with the antipsychotic drug spiperone, which is of interest for designing antip
Externí odkaz:
https://doaj.org/article/238cb5436dc34fefbac7633410b31405
Publikováno v:
IUCrJ, Vol 7, Iss 2, Pp 253-267 (2020)
Methods are presented that detect three types of aberrations in single-particle cryo-EM data sets: symmetrical and antisymmetrical optical aberrations and magnification anisotropy. Because these methods only depend on the availability of a preliminar
Externí odkaz:
https://doaj.org/article/70365abd15de459989db61c9573348cf
Autor:
Alexander M. Wolff, Iris D. Young, Raymond G. Sierra, Aaron S. Brewster, Michael W. Martynowycz, Eriko Nango, Michihiro Sugahara, Takanori Nakane, Kazutaka Ito, Andrew Aquila, Asmit Bhowmick, Justin T. Biel, Sergio Carbajo, Aina E. Cohen, Saul Cortez, Ana Gonzalez, Tomoya Hino, Dohyun Im, Jake D. Koralek, Minoru Kubo, Tomas S. Lazarou, Takashi Nomura, Shigeki Owada, Avi J. Samelson, Tomoyuki Tanaka, Rie Tanaka, Erin M. Thompson, Henry van den Bedem, Rahel A. Woldeyes, Fumiaki Yumoto, Wei Zhao, Kensuke Tono, Sebastien Boutet, So Iwata, Tamir Gonen, Nicholas K. Sauter, James S. Fraser, Michael C. Thompson
Publikováno v:
IUCrJ, Vol 7, Iss 2, Pp 306-323 (2020)
Innovative new crystallographic methods are facilitating structural studies from ever smaller crystals of biological macromolecules. In particular, serial X-ray crystallography and microcrystal electron diffraction (MicroED) have emerged as useful me
Externí odkaz:
https://doaj.org/article/6e6b471c98104285badfe50aab472279
Autor:
Andrii Ishchenko, Benjamin Stauch, Gye Won Han, Alexander Batyuk, Anna Shiriaeva, Chufeng Li, Nadia Zatsepin, Uwe Weierstall, Wei Liu, Eriko Nango, Takanori Nakane, Rie Tanaka, Kensuke Tono, Yasumasa Joti, So Iwata, Isabel Moraes, Cornelius Gati, Vadim Cherezov
Publikováno v:
IUCrJ, Vol 6, Iss 6, Pp 1106-1119 (2019)
Rational structure-based drug design (SBDD) relies on the availability of a large number of co-crystal structures to map the ligand-binding pocket of the target protein and use this information for lead-compound optimization via an iterative process.
Externí odkaz:
https://doaj.org/article/4ed362ab387b4cc5b84904da4feed3df
Publikováno v:
IUCrJ, Vol 6, Iss 1, Pp 5-17 (2019)
A new method to estimate the trajectories of particle motion and the amount of cumulative beam damage in electron cryo-microscopy (cryo-EM) single-particle analysis is presented. The motion within the sample is modelled through the use of Gaussian pr
Externí odkaz:
https://doaj.org/article/905ff63c6e084694a387f67fad969304
Autor:
Takanori Nakane
Publikováno v:
IUCrJ, Vol 8, Iss 6, Pp 853-854 (2021)
Externí odkaz:
https://doaj.org/article/017ee833897d4250aa65090f7ac7caba