Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Takanobu Shimasaki"'
Autor:
Takanobu Shimasaki, Takayuki Masaki, Kimihiko Mitsutomi, Daisuke Ueno, Koro Gotoh, Seiichi Chiba, Tetsuya Kakuma, Hironobu Yoshimatsu
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63626 (2013)
Dipeptidyl peptidase (DPP)-4 is responsible for the degradation of several peptides that contain an alanine or proline at the penultimate position or position P1. DPP-4 inhibitors (DPP-4is) have protective effects against type-2 diabetes and several
Externí odkaz:
https://doaj.org/article/db3005da470746fc828117c3999a478e
Autor:
Koro Gotoh, Megumi Inoue, Kentaro Shiraishi, Takayuki Masaki, Seiichi Chiba, Kimihiko Mitsutomi, Takanobu Shimasaki, Hisae Ando, Kansuke Fujiwara, Isao Katsuragi, Tetsuya Kakuma, Masataka Seike, Toshiie Sakata, Hironobu Yoshimatsu
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e53154 (2012)
Obesity is associated with systemic low-grade inflammation and is a risk factor for non-alcoholic fatty pancreas disease (NAFPD), but the molecular mechanisms of these associations are not clear. Interleukin (IL)-10, a potent anti-inflammatory cytoki
Externí odkaz:
https://doaj.org/article/8e0a1bb19c384707a34250de4efb98a8
Autor:
Koro Gotoh, Isao Katsuragi, Seiichi Chiba, Kansuke Fujiwara, Hisae Ando, Hironobu Yoshimatsu, Takayuki Masaki, Takanobu Shimasaki, Toshiie Sakata, Tetsuya Kakuma, Kimihiko Mitsutomi
Publikováno v:
Journal of Neurochemistry. 125:588-598
Brain-derived neurotrophic factor (BDNF), corticotropin-releasing factor (CRF), and hypothalamic neuronal histamine are anorexigenic substances within the hypothalamus. This study examined the interactions among BDNF, CRF, and histamine during the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ac9bcb80b2fe854bcd95ed7868f96c
https://doi.org/10.1111/jnc.12213
https://doi.org/10.1111/jnc.12213
Autor:
Seiichi Chiba, Hironobu Yoshimatsu, Kansuke Fujiwara, Isao Katsuragi, Hisae Ando, Toshiie Sakata, Tetsuya Kakuma, Koro Gotoh, Kimihiko Mitsutomi, Takayuki Masaki, Takanobu Shimasaki
Publikováno v:
Journal of Neuroendocrinology. 25:302-311
Understanding the molecular mechanism of the regulation of glucagon secretion is critical for treating the dysfunction of α cells observed in diabetes. Glucagon-like peptide (GLP)-1 analogues reduce plasma glucagon and are assumed to contribute to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35acff11d8c99aaf80e0f4215fd9c7f5
https://doi.org/10.1111/jne.12003
https://doi.org/10.1111/jne.12003
Autor:
Kansuke Fujiwara, Isao Katsuragi, Tomoko Nawata, Megumi Inoue, Seiichi Chiba, Tetsuya Kakuma, Takayuki Masaki, Kazue Matsuoka, Takanobu Shimasaki, Hironobu Yoshimatsu, Masataka Seike, Kentaro Shiraishi, Hisae Ando, Naoya Fukunaga, Koro Gotoh, Kohei Aoki
Publikováno v:
Nephrology Dialysis Transplantation. 28:1120-1130
Background Obesity is associated with systemic low-grade inflammation and is a risk factor for chronic kidney disease (CKD), but the molecular mechanism remains uncertain. We noticed spleen-derived interleukin (IL)-10 because it is observed that obes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ce11e519613cb918c83093d28b397b
https://doi.org/10.1093/ndt/gfs440
https://doi.org/10.1093/ndt/gfs440
Autor:
Kansuke Fujiwara, Toshiie Sakata, Hisae Ando, Koro Gotoh, Seiichi Chiba, Tetsuya Kakuma, Masataka Seike, Megumi Inoue, Takayuki Masaki, Takanobu Shimasaki, Hironobu Yoshimatsu, Isao Katsuragi
Publikováno v:
Diabetes
Obesity is associated with systemic low-grade inflammation and obesity-related metabolic disorders. Considering that obesity decreases the expression of proinflammatory cytokines in the spleen, we assessed the role of interleukin (IL)-10, an anti-inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f523f5e6fa408bac09c29f76353fd6
https://doi.org/10.2337/db11-1688
https://doi.org/10.2337/db11-1688
Autor:
Hisae Ando, Isao Katsuragi, Tetsuya Kakuma, Seiichi Chiba, Koro Gotoh, Kansuke Fujiwara, Toshiie Sakata, Hironobu Yoshimatsu, Megumi Inoue, Masataka Seike, Takayuki Masaki, Takanobu Shimasaki
Publikováno v:
Journal of Neurochemistry. 120:752-764
Obesity can be associated with systemic low-grade inflammation that contributes to obesity-related metabolic disorders. Recent studies raise the possibility that hypothalamic inflammation contributes to the pathogenesis of diet-induced obesity (DIO),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71035f8128c461671f5a770f41119684
https://doi.org/10.1111/j.1471-4159.2011.07617.x
https://doi.org/10.1111/j.1471-4159.2011.07617.x
Autor:
Koro Gotoh, Takayuki Masaki, Takanobu Shimasaki, Tetsuya Kakuma, Hironobu Yoshimatsu, Daisuke Ueno, Kimihiko Mitsutomi, Seiichi Chiba
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 5, p e63626 (2013)
PLoS ONE, Vol 8, Iss 5, p e63626 (2013)
Objective Dipeptidyl peptidase (DPP)-4 is responsible for the degradation of several peptides that contain an alanine or proline at the penultimate position or position P1. DPP-4 inhibitors (DPP-4is) have protective effects against type-2 diabetes an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c67bca89501de3812412313f296d442b
http://europepmc.org/articles/PMC3656085
http://europepmc.org/articles/PMC3656085
Autor:
Takayuki Masaki, Takanobu Shimasaki, Seiichi Chiba, Koro Gotoh, Isao Katsuragi, Toshiie Sakata, Kimihiko Mitsutomi, Hironobu Yoshimatsu, Hisae Ando, Kansuke Fujiwara, Tetsuya Kakuma
Publikováno v:
Journal of neurochemistry. 124(1)
Nesfatin-1, corticotropin-releasing hormone (CRH), thyrotropin-releasing hormone (TRH), and hypothalamic neuronal histamine act as anorexigenics in the hypothalamus. We examined interactions among nesfatin-1, CRH, TRH, and histamine in the regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad655b1aa03a677d1a6c5a38f45aaf48
https://pubmed.ncbi.nlm.nih.gov/23106615
https://pubmed.ncbi.nlm.nih.gov/23106615
Autor:
Koro, Gotoh, Megumi, Inoue, Takayuki, Masaki, Seiichi, Chiba, Takanobu, Shimasaki, Hisae, Ando, Kansuke, Fujiwara, Isao, Katsuragi, Tetsuya, Kakuma, Masataka, Seike, Toshiie, Sakata, Hironobu, Yoshimatsu
Publikováno v:
Journal of neurochemistry. 120(5)
Obesity can be associated with systemic low-grade inflammation that contributes to obesity-related metabolic disorders. Recent studies raise the possibility that hypothalamic inflammation contributes to the pathogenesis of diet-induced obesity (DIO),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f90f0e0d848aaf740f0676cba42c519f
https://pubmed.ncbi.nlm.nih.gov/22146087
https://pubmed.ncbi.nlm.nih.gov/22146087