Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Takanobu SAKURAI"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The oral administration of antioxidants may suppress UV-B-induced skin damage. HITHION YH-15, the extract of Torula yeast (Cyberlindnera jadinii), is rich in cysteine-containing peptides such as reduced and oxidized glutathione (GSH and GSSG
Externí odkaz:
https://doaj.org/article/33d09fc1d39d40e986d19e87dc0dca67
Autor:
Yoshiko Nakagawa-Nagahama, Masaki Igarashi, Masaomi Miura, Kosuke Kashiwabara, Keisuke Yaku, Yuichiro Fukamizu, Toshiya Sato, Takanobu Sakurai, Takashi Nakagawa, Takashi Kadowaki, Toshimasa Yamauchi
Publikováno v:
BMC Geriatrics, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Age-related hearing loss (ARHL) is a common phenomenon observed during aging. On the other hand, the decrease in Nicotinamide adenine dinucleotide (NAD +) levels is reported to be closely related to the age-related declines in phy
Externí odkaz:
https://doaj.org/article/9014483caae543e68adedcdbc73a2f9d
Autor:
Yuichiro Fukamizu, Yoshiaki Uchida, Akari Shigekawa, Toshiya Sato, Hisayuki Kosaka, Takanobu Sakurai
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract A decrease in the intracellular level of nicotinamide adenine dinucleotide (NAD+), an essential coenzyme for metabolic activity, causes various age-related diseases and metabolic abnormalities. Both in-vivo and in-vitro studies have shown th
Externí odkaz:
https://doaj.org/article/efb7a2f69b3b4163bfa46d7d4232e742
Autor:
Yoshiaki Uchida, Tomomi Kaneda, Mio Ono, Masao Matsuoka, Utano Nakamura, Akiko Ishida, Yoshimitsu Yamasaki, Hiroki Takeo, Takanobu Sakurai
Publikováno v:
Cosmetics, Vol 10, Iss 3, p 72 (2023)
Glutathione (GSH) is present in almost all human cells and has a beneficial effect on human skin brightness. Cysteinylglycine (Cys-Gly) and γ-glutamylcysteine (γ-Glu-Cys) are GSH synthesis components. In this study, we defined glutathione (GSH), cy
Externí odkaz:
https://doaj.org/article/2a2fed47d7a845d9838f1f7b863c895b
Autor:
Keisuke Okabe, Keisuke Yaku, Yoshiaki Uchida, Yuichiro Fukamizu, Toshiya Sato, Takanobu Sakurai, Kazuyuki Tobe, Takashi Nakagawa
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Nicotinamide mononucleotide (NNM) is an orally bioavailable NAD+ precursor that has demonstrated beneficial effects against aging and aging-associated diseases in animal models. NMN is ultimately converted to NAD+, a redox cofactor that mediates many
Externí odkaz:
https://doaj.org/article/d84f9a702e154b398b0875e024b1ed62
Publikováno v:
Journal of Pharmacological Sciences, Vol 99, Iss 3, Pp 277-286 (2005)
Nerve growth factor (NGF) is an important substance in the skin, where it can modulate nerve maintenance and repair. However, the direct link between NGF and pruritic disease such as atopic dermatitis is not yet fully understood. To determine whether
Externí odkaz:
https://doaj.org/article/08087b4f86cd40dba8bcf02d01ec6324
Autor:
Takayuki Seki, Tsuyoshi Ishimoto, Takanobu Sakurai, Yoshiko Yasuda, Kazuo Taniguchi, Mariko Doi, Mariko Sato, Richard J. Roman, Noriyuki Miyata
Publikováno v:
Journal of Pharmacological Sciences, Vol 97, Iss 1, Pp 132-137 (2005)
The present study examined the contribution of 20-hydroxy-5,8,11,14-eicosatetraenoic acid (20-HETE) in cyclosporine A (CsA)-induced renal nephrotoxicity. Treatment of rats with CsA (50 mg/kg) for 9 days induced renal damage as indicated by marked inc
Externí odkaz:
https://doaj.org/article/29be99a05d2645118f80e1033015b67e
Autor:
Banyar Than, Naing, Takami, Takizawa, Takanobu, Sakurai, Chaw, Kyi-Tha-Thu, Toshihiro, Takizawa
Publikováno v:
Histochemistry and Cell Biology. 159:363-375
LncRNA H19 serves as a regulatory RNA in mouse placental development. However, there is little information available on the in situ expression of H19 in the late-gestation mouse placenta. In this study, we performed quantitative polymerase chain reac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc4788cdf3b787d5924e067970f6866
https://doi.org/10.1007/s00418-022-02169-y
https://doi.org/10.1007/s00418-022-02169-y
Publikováno v:
Bulletin of the Chemical Society of Japan. 95(11):1518-1520
金沢大学理工学研究域物質化学系
A methylene group was introduced into the C–H bond of α-carbonyl aldonitrones by reaction with dimethylsulfoxonium methylide, producing one-carbon homologated C-methyl ketonitrones. This formal me
A methylene group was introduced into the C–H bond of α-carbonyl aldonitrones by reaction with dimethylsulfoxonium methylide, producing one-carbon homologated C-methyl ketonitrones. This formal me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0edaa4b1e71dea32c855ac00ccc1c4b5
http://hdl.handle.net/2297/00068384
http://hdl.handle.net/2297/00068384
Publikováno v:
Food Science and Technology Research. 27:615-626
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17be3c142f1d2ec0c3d3e28ffdc7a491
https://doi.org/10.3136/fstr.27.615
https://doi.org/10.3136/fstr.27.615