Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Takanobu, Araki"'
Autor:
Shinobu Takeda, Takanobu Araki, Souichirou Akamatsu, Katsuyuki Maki, Satoko Uchida, David A. Barrett, Satoru Matsumoto, Kayakiri Natsuko, Toru Nakai, Masaki Tomishima, Hiroshi Morikawa
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:1172-1175
The synthesis and antifungal activity of ASP9726, a novel echinocandin with potent Aspergillus hyphal growth inhibition and significantly improved MIC against Candida parapsilosis and echinocandin resistant-Candida is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc41697d55d5766c61efaf2465629d1
https://doi.org/10.1016/j.bmcl.2013.12.116
https://doi.org/10.1016/j.bmcl.2013.12.116
Autor:
Yusuke Daiko, Isao Yamada, Noriaki Toyoda, Takanobu Araki, Masafumi Kobune, Tetsuo Yazawa, Atsushi Mineshige
Publikováno v:
Journal of the American Ceramic Society. 93:127-131
Porous glasses (PGs) with 4 nm in diameter pores were prepared utilizing a spinodal-type phase separation of Na2O–B2O3–SiO2 glass, and their surface was modified using titanium tetraisopropoxide. Fourier transform infrared measurements revealed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bab04726b1dc76dcbd66743109e38207
https://doi.org/10.1111/j.1551-2916.2009.03381.x
https://doi.org/10.1111/j.1551-2916.2009.03381.x
Autor:
Kenichi Washizuka, Yasuhiro Matsumura, Yasuyo Tomishima, Keiko Nakano, Naoko Unami, Fujiko Takamura, Takanobu Araki, Shigeo Matsui, Minoru Sakurai, Masashi Imanishi, Takao Yamamoto, Kaori Hamada, Kouji Hattori, Hitoshi Hamashima, Nobuhiro Yamamoto, Emiko Imamura, Hirofumi Ishikawa, Koji Ueshima, Yutaka Nakajima, Susumu Toda, Shinji Itou
Publikováno v:
Journal of Medicinal Chemistry. 52:3063-3072
As an extension of research conducted on beta(3)-adrenergic receptor agonists as potential drugs for treating overactive bladder (OAB), novel series containing an acylsulfonamide moiety instead of the carboxylic acid moiety were evaluated. These comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db696b5f389955fb00201a425aef2632
https://doi.org/10.1021/jm9000709
https://doi.org/10.1021/jm9000709
Autor:
Yusuke Daiko, Shinichi Matsumoto, Keisuke Nagasaka, Takanobu Araki, Ichiro Konomi, Shin-ichi Yusa, Akihiko Koiwai, Tetsuo Yazawa, Atsushi Mineshige, Masafumi Kobune, Shigeaki Murata, Hirokazu Katayama
Publikováno v:
The Journal of Physical Chemistry C. 113:1891-1895
Porous glasses with 4 nm diameter pores were prepared utilizing a spinodal-type phase separation of Na2O−B2O3−SiO2 glass, and the surface was modified by using mercaptoalkyltrimethoxysilane with different alkyl chain length ((CH3O)3Si(CH2)n-SH, n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97bbef53076cb09a30d397bde826b4b3
https://doi.org/10.1021/jp8086094
https://doi.org/10.1021/jp8086094
Autor:
Nami Ohashi, Hiroshi Tsutsumi, Kenichi Hiramatsu, Hirokazu Tamamura, Hiroyuki Masuno, Nobutaka Fujii, Tomohiro Tanaka, Satoshi Ueda, Takanobu Araki, Shinya Oishi
Publikováno v:
Biopolymers. 88:279-289
The chemokine receptor CXCR4 possesses multiple critical functions in normal and pathologic physiology. CXCR4 is a G-protein-coupled receptor that transduces signals of its endogenous ligand, the chemokine CXCL12 (stromal cell-derived factor-1, SDF-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::494c559d75dcbb2706d0c070b167888b
https://doi.org/10.1002/bip.20653
https://doi.org/10.1002/bip.20653
Autor:
Hirokazu, Tamamura, Tomohiro, Tanaka, Hiroshi, Tsutsumi, Nami, Ohashi, Kenichi, Hiramatsu, Takanobu, Araki, Akio, Ojida, Itaru, Hamachi, Zixuan, Wang, Stephen C, Peiper, John O, Trent, Satoshi, Ueda, Shinya, Oishi, Nobutaka, Fujii
Publikováno v:
Advances in experimental medicine and biology. 611
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::442add67d0926c412bec9a0d2e7ccd61
https://pubmed.ncbi.nlm.nih.gov/19400132
https://pubmed.ncbi.nlm.nih.gov/19400132
Autor:
Naoko Unami, Minoru Sakurai, Keiko Nakano, Shinji Itou, Kenichi Washizuka, Shigeo Matsui, Kaori Hamada, Yasuhiro Matsumura, Kouji Hattori, Koji Ueshima, Takanobu Araki, Masashi Imanishi, Daisuke Tanabe, Emiko Imamura, Hirofumi Ishikawa, Susumu Toda, Masaya Orita, Yutaka Nakajima, Takao Yamamoto, Fujiko Takamura, Nobuhiro Yamamoto
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(16)
As an extension of research, we have investigated modification of left-hand side (LHS) of biphenyl analogues containing an acylsulfonamide moiety in the development of potent and selective human beta(3)-adrenergic receptor (AR) agonists. Result of st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701f9b3c86a36d8cbaa684b03b5353c4
https://pubmed.ncbi.nlm.nih.gov/19608416
https://pubmed.ncbi.nlm.nih.gov/19608416
Autor:
Nobutaka Fujii, Shinya Oishi, Zixuan Wang, Kenichi Hiramatsu, Akio Ojida, Satoshi Ueda, Takanobu Araki, Tomohiro Tanaka, Nami Ohashi, John O. Trent, Itaru Hamachi, Hiroshi Tsutsumi, Hirokazu Tamamura, Stephen C. Peiper
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9780387736563
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee0c761628164a74e49d983c45c69120
https://doi.org/10.1007/978-0-387-73657-0_65
https://doi.org/10.1007/978-0-387-73657-0_65
Autor:
Keiko Nakano, Shinji Itou, Kenichi Washizuka, Koji Ueshima, Yasuyo Tomishima, Minoru Sakurai, Yasuhiro Matsumura, Hirofumi Ishikawa, Takanobu Araki, Hitoshi Hamashima, Nobuhiro Yamamoto, Fujiko Takamura, Naoko Unami, Kaori Hamada, Yutaka Nakajima, Masashi Imanishi, Takao Yamamoto, Shigeo Matsui, Kouji Hattori, Emiko Imamura
Publikováno v:
Journal of medicinal chemistry. 51(13)
The left-hand side (LHS) and central part of our first generation biphenyl (FGB) series was modified to improve in vitro and in vivo beta3-AR potency without loss of oral bioavailability. First, in this study, we focused our efforts on replacement of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57919344cacbb694f6897cec1da43b5f
https://pubmed.ncbi.nlm.nih.gov/18553954
https://pubmed.ncbi.nlm.nih.gov/18553954
Autor:
Hiroaki Ohno, John O. Trent, Hirokazu Tamamura, Shuichi Kusano, Takanobu Araki, Nobutaka Fujii, Jerome Cluzeau, Satoshi Ueda, Zixuan Wang, Stephen C. Peiper, Hideki Nakashima, Shinya Oishi
Publikováno v:
Journal of medicinal chemistry. 50(2)
Previously, we have identified a highly potent CXCR4 antagonist 2 [cyclo(-D-Tyr1-Arg2-Arg3-Nal4-Gly5-)] and its Arg2 epimer 3 [cyclo(-D-Tyr1-D-Arg2-Arg3-Nal4-Gly5-)] by the screening of cyclic pentapeptide libraries that were designed based on the st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c97a165bf6c90a38ddaead6feec7f1
https://pubmed.ncbi.nlm.nih.gov/17228861
https://pubmed.ncbi.nlm.nih.gov/17228861