Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Takamitsu Morioka"'
Autor:
Ryoko Semba, Takamitsu Morioka, Hiromi Yanagihara, Kenshi Suzuki, Hirotaka Tachibana, Takahiro Hamoya, Yoshiya Horimoto, Tatsuhiko Imaoka, Mitsue Saito, Shizuko Kakinuma, Masami Arai
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 115082- (2023)
Externí odkaz:
https://doaj.org/article/7c34a6c7af1a410bb32cb9b2a67b4670
Autor:
Ryoko Semba, Takamitsu Morioka, Hiromi Yanagihara, Kenshi Suzuki, Hirotaka Tachibana, Takahiro Hamoya, Yoshiya Horimoto, Tatsuhiko Imaoka, Mitsue Saito, Shizuko Kakinuma, Masami Arai
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 164, Iss , Pp 114968- (2023)
Therapeutic strategies that promote read-through of a mutant gene have proved effective for certain non-neoplastic diseases. However, the efficacy of this approach is unproven regarding neoplastic diseases with germline nonsense mutations, including
Externí odkaz:
https://doaj.org/article/abe3d924125341d0b3dba68bbea70347
Autor:
Sae Sakama, Keisuke Kurusu, Mayu Morita, Takashi Oizumi, Shinya Masugata, Shohei Oka, Shinya Yokomizo, Mayumi Nishimura, Takamitsu Morioka, Shizuko Kakinuma, Yoshiya Shimada, Asako J. Nakamura
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
After the Fukushima Daiichi Nuclear Power Plant accident, there is growing concern about radiation-induced carcinogenesis. In addition, living in a long-term shelter or temporary housing due to disasters might cause unpleasant stress, which adversely
Externí odkaz:
https://doaj.org/article/a5f0afbb28bc46d5adcfce26bed4353b
Autor:
Masaaki Sunaoshi, Benjamin J. Blyth, Yi Shang, Chizuru Tsuruoka, Takamitsu Morioka, Mayumi Shinagawa, Mari Ogawa, Yoshiya Shimada, Akira Tachibana, Daisuke Iizuka, Shizuko Kakinuma
Publikováno v:
Biology, Vol 11, Iss 3, p 449 (2022)
The risk of radiation-induced carcinogenesis depends on age at exposure. We previously reported principal causative genes in lymphomas arising after infant or adult exposure to 4-fractionated irradiation as Pten or Ikzf1, respectively, suggesting tha
Externí odkaz:
https://doaj.org/article/34d20e1ece824a28b25eaefa2a5f640a
Autor:
Kazuhiro Daino, Tatsuhiko Imaoka, Takamitsu Morioka, Shusuke Tani, Daisuke Iizuka, Mayumi Nishimura, Yoshiya Shimada
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74013 (2013)
BRIP1 is a DNA helicase that directly interacts with the C-terminal BRCT repeat of the breast cancer susceptibility protein BRCA1 and plays an important role in BRCA1-dependent DNA repair and DNA damage-induced checkpoint control. Recent studies impl
Externí odkaz:
https://doaj.org/article/19b645967b984f8d880a28b2ab0adad7
Autor:
Hiromi Yanagihara, Takamitsu Morioka, Shunsuke Yamazaki, Yutaka Yamada, Hirotaka Tachibana, Kazuhiro Daino, Chizuru Tsuruoka, Yoshiko Amasaki, Mutsumi Kaminishi, Tatsuhiko Imaoka, Shizuko Kakinuma
Publikováno v:
Journal of Radiation Research. 64:622-631
Recent studies have identified interstitial deletions in the cancer genome as a radiation-related mutational signature, although most of them do not fall on cancer driver genes. Pioneering studies in the field have indicated the presence of loss of h
Autor:
Tatsuhiko Imaoka, Mayumi Nishimura, Kazuhiro Daino, Ayaka Hosoki, Ken-ichi Kudo, Daisuke Iizuka, Kento Nagata, Masaru Takabatake, Yukiko Nishimura, Toshiaki Kokubo, Takamitsu Morioka, Kazutaka Doi, Yoshiya Shimada, Shizuko Kakinuma
Publikováno v:
Radiation Protection Dosimetry. 198:1036-1046
The uncertain cancer risk of protracted radiation exposure at low dose rates is an important issue in radiological protection. Tissue stem/progenitor cells are a supposed origin of cancer and may contribute to the dose-rate effect on carcinogenesis.
Autor:
Tetsuo Nakajima, Yasuharu Ninomiya, Keiko Unno, Takamitsu Morioka, Mayumi Nishimura, Shizuko Kakinuma
Publikováno v:
Journal of Radiation Research. 63:602-608
Psychological stress affects health. Radiation workers in the medical field or astronauts living in space have possible risks of exposure to radiation, and psychological stress is considered to be easily induced in them due to activities performed in
Autor:
Hirotaka Tachibana, Kazuhiro Daino, Atsuko Ishikawa, Takamitsu Morioka, Yi Shang, Mari Ogawa, Akira Matsuura, Yoshiya Shimada, Shizuko Kakinuma
Publikováno v:
Carcinogenesis. 43:693-703
Epidemiological studies have revealed a radiation-related increase in the risk of developing acute lymphoblastic leukemia (ALL). Our recent study revealed early induction and increased risk of precursor B-cell (pB) lymphomas in mice after radiation e
Autor:
Shinya, Yokomizo, Mayumi, Nishimura, Takamitsu, Morioka, Utako, Enzaka, Chizuru, Tsuruoka, Yi, Shang, Yukiko, Nishimura, Inoue, Kazumasa, Fukushi, Masahiro, Tatsuhiko, Imaoka, Shizuko, Kakinuma, Yoshiya, Shimada
Publikováno v:
In Vivo. 36(2):618-627
Background: An enriched environment (EE) as an animal housing condition modifies apoptotic cell death and promotes cell proliferation in the central nervous system (CNS). However, few studies have examined the effects of an EE on apoptosis in non-CNS