Výsledky vyhledávání - "Takamichi Nagami"

Discovery of Novel Transient Receptor Potential Vanilloid 4 (TRPV4) Agonists as Regulators of Chondrogenic Differentiation: Identification of Quinazolin-4(3 H)-ones and in Vivo Studies on a Surgically Induced Rat Model of Osteoarthritis

Autor: Masakazu Atobe, Shuji Muramatsu, Masayuki Kitagawa, Hiroko Suzuki, Takamichi Nagami, Atsushi Watanabe, Masashi Ishiguro, Takeshi Ohno, Masashi Kawanishi

Publikováno v: Journal of medicinal chemistry. 62(3)

Osteoarthritis (OA) is a degenerative disease characterized by joint destruction and loss of cartilage. There are many unmet needs in the treatment of OA and there are few promising candidates for disease-modifying OA drugs, particularly, anabolic ag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0bffcb14f8bd5085beb937289881b3
https://pubmed.ncbi.nlm.nih.gov/30629441

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5-Aryl-1,3,4-oxadiazole-2-thiols as a New Series of trans-Cinnamate 4-Hydroxylase Inhibitors

Autor: Yuki Kataoka, Soonsung Hong, Takamichi Nagami, Shinya Kawai, Naotaka Yamada, Eiichi Kuwano

Publikováno v: Journal of Pesticide Science. 29:205-208

A series of 5-aryl-1,3,4-oxadiazole-2-thiols was found to inhibit trans-cinnamate 4-hydroxylase (C4H) from Populus kitakamiensis, which was expressed in yeast. 5-Phenyl-1,3,4-oxadiazole-2-thiol showed inhibitory activity comparable to 2-hydroxy-1-nap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5b9b061631405eda413fcb67f8634bb6
https://doi.org/10.1584/jpestics.29.205

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