Zobrazeno 1 - 10 of 50 pro vyhledávání: '"Takamasa Ohno"'
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Neoadjuvant Chemotherapy with Gemcitabine Plus Nab-Paclitaxel for Borderline Resectable Pancreatic Cancer Potentially Improves Survival and Facilitates Surgery
Autor: Yasuhisa Mori, Daisuke Kakihara, Yoshihiro Miyasaka, Nao Fujimori, Kohei Nakata, Takao Ohtsuka, Masafumi Nakamura, Takamasa Ohno, Ryota Matsuda, Yoshinao Oda, Ryuichiro Kimura
Publikováno v: Annals of Surgical Oncology. 26:1528-1534
Accumulation of evidence suggests that neoadjuvant chemotherapy improves the outcomes of borderline resectable pancreatic cancer (BRPC). Gemcitabine plus nab-paclitaxel (GnP) has been widely accepted as systemic chemotherapy for unresectable pancreat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab18741a8f48b73407bdb66c77750dc0
https://doi.org/10.1245/s10434-019-07309-8
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3
Hypoglycemic Activity and the Mechanisms of Lycium Bark Extract in db/db Mice
Autor: Yota, Shimato, Tatsuhiko, Hattori, Takamasa, Ohno
Publikováno v: Biologicalpharmaceutical bulletin. 43(6)
The extract of Lycium bark (LBE), which is the root bark of Lycium chinense, has long been used in China for hypertension, inflammation, and diabetes. LBE has been reported to ameliorate hyperglycemia in mice with alloxan-induced type 1 diabetes, but
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4947b6721dc7cce5a4c4ca78d652f5ea
https://pubmed.ncbi.nlm.nih.gov/32475916
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5
Combined therapy with cardioprotective cytokine administration and antiapoptotic gene transfer in postinfarction heart failure
Autor: Rumi Maruyama, Genzou Takemura, Akiko Tsujimoto, Hisayoshi Fujiwara, Tomoyuki Takahashi, Hiromitsu Kanamori, Shusaku Miyata, Atsushi Ogino, Shinya Minatoguchi, Masayasu Esaki, Munehiro Nakagawa, Satoshi Nagano, Hideshi Okada, Takako Fujiwara, Yiwen Li, Ken-ichiro Kosai, Takamasa Ohno, Longhu Li, Kenshi Nagashima
Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 296:H616-H626
We hypothesized that therapy, composed of antiapoptotic soluble Fas (sFas) gene transfer, combined with administration of the cardioprotective cytokine granulocyte colony-stimulating factor (G-CSF), would markedly mitigate cardiac remodeling and dysf
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9546b440000c6f2bcd590c1edeff5cb3
https://doi.org/10.1152/ajpheart.01147.2008
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6
Peroxisome Proliferator-Activated Receptor .GAMMA. Ligands Isolated from Adlay Seed (Coix lacryma-jobi L. var. ma-yuen STAPF.)
Autor: Hiroshi Yokoi, Hiroki Tanabe, Makoto Inoue, Hajime Mizukami, Takamasa Ohno, Akito Nagatsu
Publikováno v: Biological and Pharmaceutical Bulletin. 32:735-740
Through screening for natural ligands against peroxisome proliferator-activated receptor gamma (PPARgamma) using the PPARgamma luciferase reporter assay, 6 hydroxy unsaturated fatty acids were isolated from adlay seed (Coix lacryma-jobi L. var. ma-yu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b6c93ec2a833fc0fbacfa87e6eb997
https://doi.org/10.1248/bpb.32.735
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7
APPLICATION OF AN ADENOVIRAL VECTOR ENCODING SOLUBLE TRANSFORMING GROWTH FACTOR-β TYPE II RECEPTOR TO THE TREATMENT OF DIABETIC NEPHROPATHY IN MICE
Autor: Hisayoshi Fujiwara, Takako Fujiwara, Takehito Kondo, Genzou Takemura, Tomoyuki Takahashi, Takamasa Ohno, Shinya Minatoguchi, Ken-ichiro Kosai, Kazuko Goto, Rumi Maruyama, Masayasu Esaki, Ichijiro Murata
Publikováno v: Clinical and Experimental Pharmacology and Physiology. 35:1288-1293
1. In the present study, we examined the effects of inhibiting transforming growth factor (TGF)-beta in a mouse model of diabetic nephropathy. 2. An adenovirus harbouring the gene encoding soluble TGF-beta type II receptor (Ad.CAG-sTbetaRII), a compe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db7c7408c07abd4bacd2f6aa87209256
https://doi.org/10.1111/j.1440-1681.2008.04967.x
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8
Effect of a long-term treatment with a low-dose granulocyte colony-stimulating factor on post-infarction process in the heart
Autor: Hideshi Okada, Shusaku Miyata, Masayasu Esaki, Atsushi Ogino, Yiwen Li, Takako Fujiwara, Takamasa Ohno, Longhu Li, Genzou Takemura, Hiromitsu Kanamori, Munehiro Nakagawa, Hisayoshi Fujiwara, Rumi Maruyama, Shinya Minatoguchi
Publikováno v: Journal of Cellular and Molecular Medicine
Although beneficial effects of granulocyte colony-stimulating factor (G-CSF) have been demonstrated on post-myocardia infarction (MI) process, the mechanisms and feasibility are not fully agreed yet. We investigated effects of a long-term treatment w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6406b4608545b7565b13edf579dc0dc0
https://doi.org/10.1111/j.1582-4934.2008.00294.x
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9
Inhibitory effect of oral intake of natural Phellinus linteus fruit body on growth and pulmonary metastasis of B16/BL6 melanoma
Autor: Hiroki Tanabe, Yukio Ogihara, Hideki Hirayama, Takamasa Ohno, Makoto Inoue, Hajime Mizukami, Yurika Takahashi
Publikováno v: Journal of Natural Medicines. 61:438-442
In the present study, the immunotherapeutic activity of oral intake of natural Phellinus linteus fruit body (nPF) against growth and pulmonary metastasis of injected B16/BL6 melanoma cells has been examined. The nPF powder was orally administered to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4815d301a60288a62b01c8732304727a
https://doi.org/10.1007/s11418-007-0163-6
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10
Molecular Signaling Mediated by Angiotensin II Type 1A Receptor Blockade Leading to Attenuation of Renal Dysfunction-Associated Heart Failure
Autor: Longhu Li, Genzou Takemura, Yiwen Li, Takako Fujiwara, Atsushi Ogino, Hideshi Okada, Shusaku Miyata, Shinya Minatoguchi, Takehito Kondo, Takamasa Ohno, Rumi Maruyama, Hiromitsu Kanamori, Masayasu Esaki, Munehiro Nakagawa, Hisayoshi Fujiwara
Publikováno v: Journal of Cardiac Failure. 13:155-162
Background In patients with end-stage renal disease, angiotensin II type 1A receptor (AT1) blockade attenuates the associated cardiac dysfunction. We investigated the molecular signaling mediating that effect. Methods and Results We used 5/6 nephrect
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::885d65d4bac2a9c62aa370a9c090db34
https://doi.org/10.1016/j.cardfail.2006.11.005
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