Výsledky vyhledávání - "Takako Shiraki"

Engineering Design of a Spallation Reaction-Based Neutron Generator for Boron Neutron Capture Therapy

Autor: Takashi Nakamura, Takehiko Tsutsui, Mamoru Baba, Takako Shiraki, Yoshihisa Tahara, Hitoshi Yokobori, S. Yonai, Y. Oda

Publikováno v: Journal of Nuclear Science and Technology. 43:9-19

An engineering design of an epithermal neutron generator for boron neutron capture therapy (BNCT) has been completed, which utilizes the spallation reaction by protons accelerated to 50 MeV. The critical issues for realization of the neutron generato

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a258c27e4f57c983181fc5e665223c9d
https://doi.org/10.1080/18811248.2006.9711063

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In Vivo klotho Gene Delivery Protects against Endothelial Dysfunction in Multiple Risk Factor Syndrome

Autor: Yo-ichi Nabeshima, Makoto Kuro-o, Tetsuya Nakamura, Ryozo Nagai, Toru Suzuki, Masahiko Kurabayashi, Yuichiro Saito, Akihiro Iida, Yoshio Ohyama, Takako Shiraki-Iida

Publikováno v: Biochemical and Biophysical Research Communications. 276:767-772

The klotho gene, originally identified by insertional mutagenesis in mice, suppresses multiple aging phenotypes (e.g., arteriosclerosis, pulmonary emphysema, osteoporosis, infertility, and short life span). We have previously shown that mice heterozy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6f7f395860b4623282adceb7e9ff57
https://doi.org/10.1006/bbrc.2000.3470

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Evaluation of the Shielding Design around the Reactor Core in the Prototype FBR Monju

Autor: Keiko Tada, Shin Usami, Takako Shiraki, Kenji Sasaki, Masao Tabayashi

Publikováno v: Journal of Nuclear Science and Technology. 37:89-93

This paper describes shielding evaluation of the measurements around the reactor core of Monju. The measurements were performed during the system start-up tests at different power levels between 0% and 45%. The measured reaction rates have been obtai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::19fe667f5cd99715b10c65b45c720778
https://doi.org/10.1080/00223131.2000.10874852

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Improvement of multiple pathophysiological phenotypes ofklotho (kl/kl) mice by adenovirus-mediated expression of theklotho gene

Autor: Masaki Noda, Yo-ichi Nabeshima, Akihiro Iida, Takako Shiraki-Iida, Satoshi Nishikawa, Makoto Kuro-o, Hideharu Anazawa, Yoko Nabeshima

Publikováno v: The Journal of Gene Medicine. 2:233-242

Background We have established a novel mouse mutant, klotho (kl), by insertional mutation of a transgene and identified the structural gene. The mouse homozygous for the mutation exhibits multiple pathological conditions resembling age-related disord

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e8fce0f63f3837ae6b65931e1c9418cb
https://doi.org/10.1002/1521-2254(200007/08)2:4<233::aid-jgm110>3.0.co

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Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein 1

Autor: Yo-ichi Nabeshima, Akihiro Iida, Ryozo Nagai, Matsumura Yutaka, Susumu Sekine, Hideharu Anazawa, Makoto Kuro-o, Takako Shiraki-Iida, Hiroki Aizawa

Publikováno v: FEBS Letters. 424:6-10

We previously established a novel mouse model for human aging and identified the genetic foundation responsible for it. A defect in expression of a novel gene, termed klotho (kl), leads to a syndrome resembling human aging in mice. The kl gene encode

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f002f50f6fd47b4d3419f43d3676e014
https://doi.org/10.1016/s0014-5793(98)00127-6

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Mutation of the mouse klotho gene leads to a syndrome resembling ageing

Autor: Yoshio Ohyama, Hiroshi Kawaguchi, Tatsuo Suga, Hitoshi Iwasaki, Takako Shiraki-Iida, Satoshi Nishikawa, Hiroki Aizawa, Masahiko Kurabayashi, Toshihiro Utsugi, Akihiro Iida, Matsumura Yutaka, Makoto Kuro-o, Yo-ichi Nabeshima, Eisuke Kume, Tadashi Kaname, Ryozo Nagai

Publikováno v: Nature. 390:45-51

A new gene, termed klotho, has been identified that is involved in the suppression of several ageing phenotypes. A defect in klotho gene expression in the mouse results in a syndrome that resembles human ageing, including a short lifespan, infertilit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2675398ebac5e93ea9fb98469295590
https://doi.org/10.1038/36285

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Establishment and Activity of AESJ-Collaboration Task Force(CTF)

Autor: Akio Ito, Shinichiro Sato, Sumi Yokoyama, Mitsuru Uesaka, Takako Shiraki, Hidemi Ogawa

Publikováno v: Journal of the Atomic Energy Society of Japan. 57:61-62

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::11c903a26ba4fb2c8960d6fe5413c584
https://doi.org/10.3327/jaesjb.57.1_61

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Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein

Autor: Takako Shiraki-Iida, Hiroki Aizawa, Matsumura Yutaka, Ryozo Nagai, Yo-ichi Nabeshima, Makoto Kuro-o

Publikováno v: Biochemical and biophysical research communications. 242(3)

Inactivation of the klotho (kl) gene in mice results in multiple disorders that resemble human aging. The mouse kl gene encodes a novel single-pass membrane protein with homology to beta-glucosidases. In this study, we have isolated a human homologue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16af51af2e44425a1a3ed8dca8c0b486
https://pubmed.ncbi.nlm.nih.gov/9464267

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