Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Takako Ohyama"'
Publikováno v:
JACS Au, Vol 4, Iss 4, Pp 1323-1333 (2024)
Externí odkaz:
https://doaj.org/article/e8b9c6f97c014e32a6daf0c6fb0dfbc4
Autor:
Hazuki Takahashi, Ana Kozhuharova, Harshita Sharma, Masakazu Hirose, Takako Ohyama, Francesca Fasolo, Toshio Yamazaki, Diego Cotella, Claudio Santoro, Silvia Zucchelli, Stefano Gustincich, Piero Carninci
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0183229 (2018)
SINEUPs are antisense long noncoding RNAs, in which an embedded SINE B2 element UP-regulates translation of partially overlapping target sense mRNAs. SINEUPs contain two functional domains. First, the binding domain (BD) is located in the region anti
Externí odkaz:
https://doaj.org/article/c97deee961594180b4f5b1535889a7a8
Autor:
Hazuki Takahashi, Piero Carninci, Stefano Gustincich, Takako Ohyama, Toshio Yamazaki, Harshita Sharma, Yoshitaka Ishii
Publikováno v:
Nucleic Acids Research
Long non-coding RNAs (lncRNAs) are attracting widespread attention for their emerging regulatory, transcriptional, epigenetic, structural and various other functions. Comprehensive transcriptome analysis has revealed that retrotransposon elements (RE
Autor:
Ayano Murai-Takeda, Takeshi Hayashi, Takako Ohyama, Kazunori Utsunomiya, Katsuyoshi Tojo, Kenichi Yokota, Naoko Tajima, Isao Kurihara, Hiroshi Itoh, Masaya Sakamoto, Yuko Mitsuishi, Kennosuke Ohashi, Rie Jo, Hirotaka Shibata
Publikováno v:
International Heart Journal. 58:794-802
Activation of mineralocorticoid receptor (MR) is shown in resistant hypertension including diabetes mellitus. Although protein kinase C (PKC) signaling is involved in the pathogenesis of diabetic complications, an association between PKC and MR is no
Autor:
Atsuya Momotake, Tomokazu Shibata, Yusaku Nakayama, Yasuhiko Yamamoto, Hikaru Hemmi, Takako Ohyama, Haruka Araki, Kosuke Hayasaka, Kentaro Ochi, Masaki Hagihara, Ryosuke Shinomiya
Publikováno v:
SC30201812260003
NARO成果DBd
NARO成果DBd
Heme in its ferrous and ferric states [heme(Fe2+) and heme(Fe3+), respectively] binds selectively to the 3′-terminal G-quartet of all parallel-stranded monomeric G-quadruplex DNAs formed from inosine(I)-containing sequences, i.e., d(TAGGGTGGGTTGGGT
Autor:
Masato Katahira, Masashi Inada, Akira Matsuda, Naonori Inoue, Noriaki Minakawa, Akimasa Matsugami, Takako Ohyama
Publikováno v:
Nucleic Acids Research
Fully modified 4'-thioDNA, an oligonucleotide only comprising 2'-deoxy-4'-thionucleosides, exhibited resistance to an endonuclease, in addition to preferable hybridization with RNA. Therefore, 4'-thioDNA is promising for application as a functional o
Publikováno v:
Seibutsu Butsuri. 47:023-028
A G-quadruplex DNA is composed of stacked G-quartets, each of which involves the planar association of four guanine bases. The size and planarity of a G-quartet are well-suited for interacting with a porphyrin ring through π-π stacking. We have dem
Publikováno v:
Biochemistry. 45:6765-6772
A water-soluble cationic porphyrin, 5,10,15,20-tetrakis(N-methylpyridinium-4-yl)-21H,23H-porphyrin (TmPyP4), has been studied extensively because of its unique physicochemical properties that lead to interactions with nucleic acids, as well as its th
Publikováno v:
Biophysical Chemistry. 113:53-59
Characterization of the interaction between DNA and small organic compounds is of considerable importance for gaining insights into the mechanism underlying molecular recognition, which could be highly relevant to drug design. In the present study, t
Autor:
Mayumi Hagiwara, Yasuoki Murakami, Takako Ohyama, Hideharu Suzuki, Yuusaku Yokoyama, Minoru Unemoto
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :1717-1724
Total syntheses of naturally occurring 4,8-dioxygenated β-carboline alkaloids 2a, 2d, 2g, and 2h are described. The synthetic route involves two methodologies that we developed; (i) an improved Fischer indolization for the synthesis of a 7-oxygenate