Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Takako Nirei"'
Autor:
Takako Nirei, Toshiaki Watanabe, Soichiro Ishihara, Toshiaki Tanaka, Kazushige Kawai, Keisuke Hata, Tomomichi Kiyomatsu, H. Nozawa
Publikováno v:
Journal of Surgical Research. 218:334-340
Background We investigated the potential of nanomedicine in loading the oxaliplatin parent complex (1,2-diaminocyclohexane)platinum(II)-loaded polymeric micelles (DACHPt/m) against multiple liver metastases from colon cancer in a mouse model. Materia
Autor:
Toshiaki Watanabe, Hiroaki Nozawa, Eiji Sunami, Masaya Hiyoshi, Takeshi Nishikawa, Joji Kitayama, Junichiro Tanaka, Shinsuke Kazama, Takamitsu Kanazawa, Soichiro Ishihara, Takako Nirei, Tomomichi Kiyomatsu, Hironori Yamaguchi, Keisuke Hata, Kazushige Kawai, Toshiaki Tanaka, Nelson H. Tsuno
Publikováno v:
Journal of Clinical Medicine Research
Rectovaginal fistula is a rare complication of ulcerative colitis (UC) regardless of surgical history of rectum. Various surgical treatment modalities for the closure of rectovaginal fistula have been developed, but a radically curative therapy remai
Autor:
Noriko Tada, Koji Murono, Kazushige Kawai, Soichiro Ishihara, Nelson H. Tsuno, Eiji Sunami, Toshiaki Watanabe, Takako Nirei, Joji Kitayama
Publikováno v:
Oncology Reports. 31:463-471
In the present study, we aimed to characterize the predictive value of cytokines/chemokines in rectal cancer (RC) patients receiving chemoradiation therapy (CRT). Blood samples were obtained pre- and post-CRT from 35 patients with advanced RC, who re
Autor:
Kazushige Kawai, Masaya Hiyoshi, Koji Murono, Takako Nirei, Toshiaki Watanabe, Eiji Sunami, Nelson H. Tsuno, Noriko Tada, Koki Takahashi, Kazuhito Sasaki, Kumiko Hongo, Manabu Kaneko, Hirokazu Nagawa, Joji Kitayama
Publikováno v:
Journal of Surgical Research. 182:75-84
Background A hypoxic environment exists in most solid tumors because in rapidly growing tumors, the development of angiogenic vasculature is heterogenous, usually not enough to overcome the necessary oxygen supply. In an ischemic condition, cancer ce
Autor:
Takako Nirei, Daisuke Soma, Hiroshi Nagata, Jun Yamada, Eiji Sunami, Toshiaki Watanabe, Kazushige Kawai, Joji Kitayama, Yoshiro Kubota, Soichiro Ishihara, Yuji Kondo, Shinsuke Kazama
Publikováno v:
World Journal of Surgical Oncology
Background Mucinous cystadenocarcinoma is the second most common etiology of appendiceal mucocele. We report a relatively rare case of a giant appendiceal mucocele caused by mucinous cystadenocarcinoma, which occupied the entire abdomen of an adult w
Autor:
Takako Nirei, Nelson H. Tsuno, Noriko Tada, Manabu Kaneko, Koji Murono, Koki Takahashi, Eiji Sunami, Kumiko Hongo, Kazushige Kawai, Joji Kitayama, Kazuhito Sasaki, Masaya Hiyoshi
Publikováno v:
Anti-Cancer Drugs. 23:675-682
Autophagy is a complex of adaptive cellular response that enhances cancer cell survival in the face of cellular stresses such as chemotherapy. Recently, chloroquine diphosphate (CQ), a widely used antimalarial drug, has been studied as a potential in
Autor:
Masahiro Ishimaru, Osamu Uemichi, Takako Nirei, Satoshi Yamamoto, Shin Sasaki, Hiroyuki Suzuki
Publikováno v:
Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association). 69:3164-3167
透析患者に発症した特発性小腸穿孔の1例を経験したので報告する.症例は64歳,女性.5日前から持続する腹痛を主訴に来院した.既往歴にネフローゼ症候群,慢性腎不全,全身性エリテ
Autor:
Tomohiro Tada, Junko Kishikawa, Masaya Hiyoshi, Tsuyoshi Ozawa, Hironori Yamaguchi, Eiji Sunami, Takamitsu Kanazawa, Shinsuke Kazama, Kanae Kubo, Toshiaki Watanabe, Junichiro Tanaka, Kazuhiko Yamamoto, Mihoko Shibuya, Joji Kitayama, Kazushige Kawai, Takako Nirei, Soichiro Ishihara, Toshiaki Tanaka, Tomomichi Kiyomatsu, Hirofumi Shoda, Shuji Sumitomo
Publikováno v:
Internal medicine (Tokyo, Japan). 54(7)
We herein report the case of a 42-year-old man with a one-year history of ulcerative colitis who presented with exacerbated bloody diarrhea, a productive cough and increasing breathing difficulties. Colonoscopy revealed typical deep ulcers in the rec
Autor:
Koji Murono, Noriko Tada, Joji Kitayama, Shigenobu Emoto, Koki Takahashi, Masaya Hiyoshi, Eiji Sunami, Manabu Kaneko, Nelson H. Tsuno, Yuuki Iida, Junko Kishikawa, Hiroaki Nozawa, Takako Nirei, Toshiaki Watanabe
Publikováno v:
Journal of cancer research and clinical oncology. 140(5)
Temsirolimus (TEM) is a novel, water-soluble mammalian target of rapamycin (mTOR) inhibitor that has shown activity against a wide range of cancers in preclinical models, but its efficacy against colorectal cancer (CRC) has not been fully explored. W
Autor:
Koji, Murono, Nelson H, Tsuno, Kazushige, Kawai, Kazuhito, Sasaki, Kumiko, Hongo, Manabu, Kaneko, Masaya, Hiyoshi, Noriko, Tada, Takako, Nirei, Eiji, Sunami, Koki, Takahashi, Joji, Kitayama
Publikováno v:
Anticancer research. 32(3)
Cancer cells can acquire resistance to therapy under hypoxic condition. We aimed to investigate the mechanisms regulating chemoresistance induced by hypoxia.Human colorectal cancer cells, HT-29 and SW480, were cultured under hypoxic conditions and th