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Autor:
Ken Ichi Yoshida, Isao Yasumatsu, Takeshi Isoyama, Yumi Matsui, Fumie Tanzawa, Yutaka Ikeno, Shin Iimura, Hiroyuki Hanzawa, Takako Nawano, Osamu Ubukata, Hajime Fukano
Publikováno v:
Acta Crystallographica Section F Structural Biology Communications. 74:156-160
Mitogen-activated protein kinase (MAPK)-interacting kinases 1 (Mnk1) and 2 (Mnk2) modulate translation initiation through the phosphorylation of eukaryotic translation initiation factor 4E, which promotes tumorigenesis. However, Mnk1 and Mnk2 are dis