Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Takako Hirano"'
Autor:
Makoto Nagashima, Hiroki Nakamura, Hiroki Hosaka, Takako Hirano, Wataru Hakamata, Toshiyuki Nishio
Publikováno v:
Glycobiology. 32:540-549
Bifidobacterium pseudocatenulatum grows well in the early stages of cultivation in medium containing sucrose (Suc), whereas its growth in medium containing the analogue disaccharide N-acetylsucrosamine (SucNAc) tends to exhibit a considerable delay.
Publikováno v:
Molbank, Vol 2018, Iss 1, p M973 (2018)
In this study, all four stereoisomers of tryptoline or tetrahydro-β-carboline were synthesized in high yields by the catalyst-free amidation of methyl ester using methylamine under mild conditions. All isomers of the obtained amide and the precursor
Externí odkaz:
https://doaj.org/article/0db8593d21724f3c857812e6536dc912
Publikováno v:
Bulletin of Applied Glycoscience. 11:72-78
Autor:
Wataru Hakamata, Kaho Goto, Sakiko Ishiwata, Rieka Ouki, Riku Sakai, Arisa Iizuka, Shuta Yano, Takako Hirano, Toshiyuki Nishio
Publikováno v:
Molbank, Vol 2016, Iss 3, p M905 (2016)
Environmentally friendly and straightforward methods for creating biofuels are required to promote biofuel use. Therefore, we present here a convenient and environmentally friendly direct self-aldol reaction of acetaldehyde in 100 mM borate buffer (p
Externí odkaz:
https://doaj.org/article/81d2097dde7e4bb281d4d87a3ac2d358
Autor:
Toshiyuki Nishio, Sayaka Shirai, Takako Hirano, Wataru Hakamata, Mitsuru Tashiro, Sora Fujita, Hiroki Hosaka
Publikováno v:
Journal of Applied Glycoscience
Utilizing transglycosylation reaction catalyzed by β- N -acetylhexosaminidase of Stenotrophomonas maltophilia , β-D-fructofuranosyl-(2↔1)-α- N , N ´diacetylchitobioside (GlcNAc 2 -Fru) was synthesized from N -acetylsucrosamine and N , N ´-diac
Publikováno v:
Bulletin of Applied Glycoscience. 10:184-193
Autor:
Kazuki Miura, Chihiro Onodera, Takako Hirano, Wataru Hakamata, Motonari Takagi, Ryosuke Koyama, Toshiyuki Nishio
Publikováno v:
Chemical and Pharmaceutical Bulletin. 68:753-761
The genes GLB1 and GALC encode GLB1 isoform 1 and galactocerebrosidase, respectively, which exhibit β-galactosidase activity in human lysosomes. GLB1 isoform 1 has been reported to play roles in rare lysosomal storage diseases. Further, its β-galac
Autor:
Kazuki Miura, Yuka Aoyama, Toshiyuki Nishio, Takako Hirano, Yurika Natsu, Wataru Hakamata, Ryosuke Koyama
Publikováno v:
Chemical and Pharmaceutical Bulletin. 68:526-533
Inhibitors of human β-N-acetyl-D-hexosaminidase (hHEX) A and human O-GlcNAcase (hOGA) reportedly play roles in multiple diseases, suggesting their potential for pharmacological chaperone (PC) therapy of Sandhoff disease (SD) and Tay-Sachs disease (T
Autor:
Yui Kano, Kazuki Miura, Ryosuke Koyama, Takako Hirano, Wataru Hakamata, Yuta Soeda, Toshiyuki Nishio, Kaori Kikushima, Ayaka Mizutani
Publikováno v:
Bioorganicmedicinal chemistry. 28(11)
Effective chemotherapy for solid cancers is challenging due to a limitation in permeation that prevents anticancer drugs from reaching the center of the tumor, therefore unable to limit cancer cell growth. To circumvent this issue, we planned to appl
Publikováno v:
Chemical and Pharmaceutical Bulletin. 66:678-681
Three Golgi mannosidases (GMs), namely Golgi α-mannosidases IA, IB, and IC, remove mannose residues from N-glycans and regulate the quality control and transportation of nascent proteins. GM inhibitors regulate several biological events such as cell