Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Takakazu Otsubo"'
Autor:
Takakazu Otsubo, Kazunori Tomono, Takayoshi Tashiro, Yoshihiro Yamamoto, Satoru Sonoke, Junzo Seki, Yoshifumi Tomii, Shigefumi Maesaki, Shigeru Kohno, Mohammad Ashraf Hossain
Publikováno v:
Antimicrobial Agents and Chemotherapy. 43:471-475
We evaluated the in vitro and in vivo potencies of a new lipid nanosphere that incorporates amphotericin B (AmB), NS-718, against Aspergillus fumigatus. The in vitro activity of NS-718 (the MIC at which 90% of strains are inhibited [MIC90], 0.25 mg/m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a0b5e2d85f04505c07066c7e4d5246
https://doi.org/10.1128/aac.43.3.471
https://doi.org/10.1128/aac.43.3.471
Autor:
Yoshitsugu Miyazaki, Takayoshi Tashiro, Shigefumi Maesaki, Tomoko Takizawa, Kazuo Maruyama, Takakazu Otsubo, Shigeru Kohno, Eitaro Tanaka, Kazunori Tomono, Kunikazu Moribe
Publikováno v:
Antimicrobial Agents and Chemotherapy. 42:40-44
We investigated the efficacy of long-circulating immunoliposomal amphotericin B (AmB) against invasive pulmonary aspergillosis in mice using three types of liposomal AmB: conventional liposomal AmB (AmBisome), a long-circulating liposomal AmB and pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ea8e1f240bcf28f7a3b47127f6635d
https://doi.org/10.1128/aac.42.1.40
https://doi.org/10.1128/aac.42.1.40
Publikováno v:
Advanced Drug Delivery Reviews. 24:325-329
Liposomal amphotericin B (L-AmB) is useful for clinical applications because of the decreased toxicity of amphotericin B (AmB). However, liposomes are rapidly removed from the circulation by the reticulo-endothelial system (RES), and show poor target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2574fd121190de2b3c5e07304a523227
https://doi.org/10.1016/s0169-409x(96)00474-7
https://doi.org/10.1016/s0169-409x(96)00474-7
Autor:
Takayoshi Tashiro, Takashige Miyazaki, Tetsuhiro Noda, Yoshihiro Yamamoto, Sadanori Kawamoto, Shigeru Kohno, Hiroshi Kakeya, Sumio Kawamura, Kohei Hara, Shigefumi Maesaki, Takakazu Otsubo, Hironobu Koga, Eisuke Sasaki, Mitsuo Kaku, Kazunori Tomono
Publikováno v:
Journal of Infection and Chemotherapy. 1:127-132
This study evaluated combination therapy with miconazole and flucytosine for treating deep seated mycosis. Both mycological and clinical efficacy against candidemia and pulmonary cryptococcosis were satisfactory: All four isolatedCandida spp. were er
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::776e484c4b22650a2c6b577b17a7b0f8
https://doi.org/10.1007/bf02348757
https://doi.org/10.1007/bf02348757
Autor:
Shigeru Kohno, Mitsuo Kaku, Kohei Hara, Tomiko Takase, Norihiko Mori, Yuichi Inoue, Tohru Ishino, Tuyoshi Fujii, Takakazu Otsubo, Hironobu Koga
Publikováno v:
Internal Medicine. 34:485-490
Forty-four patients with catheter-related infection admitted to Hokusho Central Hospital between 1985 and 1991 were studied retrospectively. The rate of catheter-related fungemia or bacteremia to all corresponding cases of fungemia and bacteremia inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93ba83b3a2d79c01fa8a2e8314dbc27d
https://doi.org/10.2169/internalmedicine.34.485
https://doi.org/10.2169/internalmedicine.34.485
Autor:
Hiroyuki KOBAYASHI, Shin KAWAI, Susumu SAKAYORI, Masamitsu KANEKO, Yasushi ITO, Yoshihito UJIIE, Kenji KOBAYASHI, Hitoshi IMAIZUMI, Shuitsu HOSHI, Shigeatsu ENDO, Ryouichi MOTOKI, Hitoshi INOUE, Gouichi ENDO, Masaaki ARAKAWA, Kouichi WADA, Hiroyuki HIRASAWA, Shigeto ODA, Hidetoshi SHIGA, Kunio KOBAYASHI, Takashi HIGO, Otohiko KUNII, Yasuo ONO, Hajime NISHIYA, Takeshi SATO, Kyuya ISHIBIKI, Masakazu UEDA, Kaoru SHIMADA, Satoshi KIMURA, Iwao KOMURO, Hajime GOTO, Takashi INAMATSU, Makiko FUKAYAMA, Izumi HAYASHI, Masao ICHIKI, Shuji SHIMAZAKI, Tetsuo YUKIOKA, Shoichi OOTA, Yasuyuki YONEDA, Takashi OOWADA, Katsuhiko SUGIMOTO, Shoichiro IRIMAJIRI, Yasuo OOSONE, Jyun TAKEZAWA, Toshio FUKUOKA, Jirou YURA, Nagao SHINAGAWA, Shu ISHIKAWA, Hirotada KATSUYA, Kiyoshi ISHIKAWA, Toshiyuki YAMAMOTO, Kanzou SUZUKI, Touru MATSUURA, Ikuto YOSHIYA, Nobuyuki TAENAKA, Kikushi KATSURADA, Hiroshi NISHIO, Keiji KUMON, Naoki YAHAGI, Ikuto SAKATA, Jirou MARUYAMA, Hiroshi TANIMURA, Makoto IWAHASHI, Shizuma MIZOBATA, Masahiro SHINOZAKI, Toshio NAKA, Chiiho FUJII, Mitsuhiro FUKUDA, Shinichi ISHIMATSU, Rinzo SOEJIMA, Yoshihito NIKI, Hiroshi TATARA, Takashi YOKOYAMA, Takashi KODAMA, Hiroaki TSUMURA, Katsurou YAGAWA, Nobuo KAKU, Mitsuo SOU, Toshimi TSUNEYOSHI, Kohei HARA, Shigeru KOHNO, Hironobu KOGA, Kazunori TOMONO, Yuuichi INOUE, Takakazu OTSUBO, Sadahiro ASAI, Hideo MASHIMOTO, Shouichi SATO, Jun ARAKI, Michio OGAWA, Satoshi IKEI, Masao YOSHIDA, Katsuya INADA, Kenji TADOKORO
Publikováno v:
Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases. 68(1)
The efficacy, safety and usefulness of murine anti-endotoxin monoclonal IgM antibody "E5, an intravenous dose of 2 mg/kg" were evaluated in 88 patients with suspected Gram-negative sepsis from 37 institutes in Japan. Out of these, 74 patients were ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9691b5d850be9a6bfb326f7ba142ea
https://pubmed.ncbi.nlm.nih.gov/8138682
https://pubmed.ncbi.nlm.nih.gov/8138682