Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Takakazu Mizuno"'
Autor:
Toshiyuki Mio, Nobuya Ishii, Haruhiko Sato, Hiroshi Koyano, Hirosato Ebiike, Kiyomoto Ogasawara, Kiyoaki Sakata, Toshihiko Fujii, Yukako Tachibana, Yasuko Satoh, Masami Hasegawa, Hiromi Tanimura, Nukinori Akiyama, Kana Horiguchi-Takei, Takakazu Mizuno, Yoshito Nakanishi, Natsuki Hamanaka
Targeting genetic alterations of oncogenes by molecular-targeted agents (MTA) is an effective approach for treating cancer. However, there are still no clinical MTA options for many cancers, including esophageal cancer. We used a short hairpin RNA li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bbd4023fb895d8493a934a57935e6bd
https://doi.org/10.1158/0008-5472.c.6511173
https://doi.org/10.1158/0008-5472.c.6511173
Autor:
Toshiyuki Mio, Nobuya Ishii, Haruhiko Sato, Hiroshi Koyano, Hirosato Ebiike, Kiyomoto Ogasawara, Kiyoaki Sakata, Toshihiko Fujii, Yukako Tachibana, Yasuko Satoh, Masami Hasegawa, Hiromi Tanimura, Nukinori Akiyama, Kana Horiguchi-Takei, Takakazu Mizuno, Yoshito Nakanishi, Natsuki Hamanaka
Anti-proliferative activity against KYSE70 expressing mock, YES1-WT and SRC-WT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::649c7c065bf23930b083930f4c156f76
https://doi.org/10.1158/0008-5472.22422285.v1
https://doi.org/10.1158/0008-5472.22422285.v1
Autor:
Toshiyuki Mio, Nobuya Ishii, Haruhiko Sato, Hiroshi Koyano, Hirosato Ebiike, Kiyomoto Ogasawara, Kiyoaki Sakata, Toshihiko Fujii, Yukako Tachibana, Yasuko Satoh, Masami Hasegawa, Hiromi Tanimura, Nukinori Akiyama, Kana Horiguchi-Takei, Takakazu Mizuno, Yoshito Nakanishi, Natsuki Hamanaka
Kinase inhibitory activity of CH6953755, dasatinib and bosutinib against 39 kinases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9707988baa40410f9995d8e113650fb0
https://doi.org/10.1158/0008-5472.22422297.v1
https://doi.org/10.1158/0008-5472.22422297.v1
Autor:
Toshiyuki Mio, Nobuya Ishii, Haruhiko Sato, Hiroshi Koyano, Hirosato Ebiike, Kiyomoto Ogasawara, Kiyoaki Sakata, Toshihiko Fujii, Yukako Tachibana, Yasuko Satoh, Masami Hasegawa, Hiromi Tanimura, Nukinori Akiyama, Kana Horiguchi-Takei, Takakazu Mizuno, Yoshito Nakanishi, Natsuki Hamanaka
Kinase selectivity profile of CH6953755. The values of % competition at 0.01 or 0.1 μmol/L CH6953755 in DiscoveRx's KINOMEscan for 456 kinases including mutated kinases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa43d1aa4a3202141326031990c4f84
https://doi.org/10.1158/0008-5472.22422291.v1
https://doi.org/10.1158/0008-5472.22422291.v1
Autor:
Toshiyuki Mio, Nobuya Ishii, Haruhiko Sato, Hiroshi Koyano, Hirosato Ebiike, Kiyomoto Ogasawara, Kiyoaki Sakata, Toshihiko Fujii, Yukako Tachibana, Yasuko Satoh, Masami Hasegawa, Hiromi Tanimura, Nukinori Akiyama, Kana Horiguchi-Takei, Takakazu Mizuno, Yoshito Nakanishi, Natsuki Hamanaka
Supplementary materials and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6532c4dee84d4dce36848778d941fa1a
https://doi.org/10.1158/0008-5472.22422303.v1
https://doi.org/10.1158/0008-5472.22422303.v1
Autor:
Toshiyuki Mio, Nobuya Ishii, Haruhiko Sato, Hiroshi Koyano, Hirosato Ebiike, Kiyomoto Ogasawara, Kiyoaki Sakata, Toshihiko Fujii, Yukako Tachibana, Yasuko Satoh, Masami Hasegawa, Hiromi Tanimura, Nukinori Akiyama, Kana Horiguchi-Takei, Takakazu Mizuno, Yoshito Nakanishi, Natsuki Hamanaka
Supplementary Figure S1. YES1 gene is amplified and YES1 expression is related to poor prognosis in esophageal cancer and lung cancer in clinical. Supplementary Figure S2. YES1 gene amplification including the upregulation of YES1 expression. Supplem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62eacf9b0f2cac370e83a2fdeb299d99
https://doi.org/10.1158/0008-5472.22422300
https://doi.org/10.1158/0008-5472.22422300
Autor:
Toshiyuki Mio, Nobuya Ishii, Haruhiko Sato, Hiroshi Koyano, Hirosato Ebiike, Kiyomoto Ogasawara, Kiyoaki Sakata, Toshihiko Fujii, Yukako Tachibana, Yasuko Satoh, Masami Hasegawa, Hiromi Tanimura, Nukinori Akiyama, Kana Horiguchi-Takei, Takakazu Mizuno, Yoshito Nakanishi, Natsuki Hamanaka
Anti-proliferative activity of various MTAs against 66 cancer cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5d825d131610570958955294ac5086
https://doi.org/10.1158/0008-5472.22422288
https://doi.org/10.1158/0008-5472.22422288
Autor:
Kiyomoto Ogasawara, Natsuki Hamanaka, Nukinori Akiyama, Takakazu Mizuno, Toshiyuki Mio, Toshihiko Fujii, Hirosato Ebiike, Kiyoaki Sakata, Hiroshi Koyano, Hiromi Tanimura, Masami Hasegawa, Nobuya Ishii, Kana Horiguchi-Takei, Yukako Tachibana, Haruhiko Sato, Yoshito Nakanishi, Yasuko Satoh
Publikováno v:
Cancer Research. 79:5734-5745
Targeting genetic alterations of oncogenes by molecular-targeted agents (MTA) is an effective approach for treating cancer. However, there are still no clinical MTA options for many cancers, including esophageal cancer. We used a short hairpin RNA li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6be452a603fcba09179dce0b446c5720
https://doi.org/10.1158/0008-5472.can-18-3376
https://doi.org/10.1158/0008-5472.can-18-3376
Autor:
Toshihiko Fujii, Munehiro Yuhki, Satoshi Aida, Takakazu Mizuno, Kiyoaki Sakata, Hiroshi Sakamoto, Yukiko Sonobe
Publikováno v:
Cancer Chemotherapy and Pharmacology. 79:1187-1193
Although treatment of melanoma with BRAF inhibitors and immune checkpoint inhibitors achieves a high response rate, a subset of melanoma patients with intrinsic and acquired resistance are insensitive to these therapeutics, so to improve melanoma the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59725821f0454da82eed8da2eef6ad81
https://doi.org/10.1007/s00280-017-3317-6
https://doi.org/10.1007/s00280-017-3317-6
Autor:
Natsuki, Hamanaka, Yoshito, Nakanishi, Takakazu, Mizuno, Kana, Horiguchi-Takei, Nukinori, Akiyama, Hiromi, Tanimura, Masami, Hasegawa, Yasuko, Satoh, Yukako, Tachibana, Toshihiko, Fujii, Kiyoaki, Sakata, Kiyomoto, Ogasawara, Hirosato, Ebiike, Hiroshi, Koyano, Haruhiko, Sato, Nobuya, Ishii, Toshiyuki, Mio
Publikováno v:
Cancer research. 79(22)
Targeting genetic alterations of oncogenes by molecular-targeted agents (MTA) is an effective approach for treating cancer. However, there are still no clinical MTA options for many cancers, including esophageal cancer. We used a short hairpin RNA li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::809bcbc6c989892211ffe34ec62180e9
https://pubmed.ncbi.nlm.nih.gov/31772072
https://pubmed.ncbi.nlm.nih.gov/31772072