Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Takahito Otani"'
Autor:
Mineyuki Mizuguchi, Takeshi Yokoyama, Takahito Otani, Shiori Kuribara, Yuko Nabeshima, Takayuki Obita, Masato Hirata, Keiichi Kawano
Publikováno v:
FEBS Letters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2dc43a6d8d916e909af093f3cfdbb6e
https://doi.org/10.1002/1873-3468.14618
https://doi.org/10.1002/1873-3468.14618
Autor:
Shoko Ishikawa, Misaki Nikaido, Takahito Otani, Kayoko Ogata, Hiroshi Iida, Yuko Inai, Sachio Tamaoki, Tetsuichiro Inai
Publikováno v:
Microscopy. 71:152-160
Retinoic acid (RA) plays an important role in epithelial homeostasis and influences the morphology, proliferation, differentiation and permeability of epithelial cells. Mouse keratinocytes, K38, reconstituted non-keratinized stratified epithelium in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e92973fcaa9afb0f358f00200fd42841
https://doi.org/10.1093/jmicro/dfac007
https://doi.org/10.1093/jmicro/dfac007
Autor:
Hiroshi Iida, Tetsuichiro Inai, Yuko Inai, Shoji Miyazono, Norio Kitagawa, Kayoko Ogata, Takahito Otani, Takashi Matsuura
Publikováno v:
Histochemistry and cell biology. 153(4)
Keratinocytes take up serum-derived retinol (vitamin A) and metabolize it to all-trans-retinoic acid (atRA), which binds to the nuclear retinoic acid receptor (RAR). We previously reported that serum-affected keratinocyte differentiation and function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edaec0fa98a82087b0e459b4291e0aa6
https://pubmed.ncbi.nlm.nih.gov/32006103
https://pubmed.ncbi.nlm.nih.gov/32006103
Autor:
Hiroshi Kojima, Kayoko Ogata, Akane Ozaki, Hiroshi Iida, Tetsuichiro Inai, Takahito Otani, Norio Kitagawa
Publikováno v:
Histochemistry and Cell Biology. 151:315-326
Vitamin A, which is found in serum, is known to affect keratinocyte proliferation, epidermal differentiation, and keratinization. In mice, stratified epithelia in the oral cavity, esophagus, and forestomach are keratinized; however, these epithelia a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29cecbcaf63394369b1676226509eaba
https://doi.org/10.1007/s00418-018-1741-2
https://doi.org/10.1007/s00418-018-1741-2
Autor:
Jing Gao, Takahito Otani, Masato Hirata, Satoru Mukai, Tomoyo Kawakubo-Yasukochi, Ronghao Tang, Akiko Mizokami, Sakura Chishaki, Hiroshi Takeuchi, Eijiro Jimi, Takashi Kanematsu, Tomomi Sano, Miho Matsuda
Publikováno v:
The Journal of Biological Chemistry
The G protein-coupled receptor GPRC6A regulates various physiological processes in response to its interaction with multiple ligands, such as extracellular basic amino acids, divalent cations, testosterone, and the uncarboxylated form of osteocalcin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1071bba384b52dd2c1bcbfadb6f1ee23
https://pubmed.ncbi.nlm.nih.gov/33428938
https://pubmed.ncbi.nlm.nih.gov/33428938
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. :PO3-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::197742a94b72823be101dfdb73a35be7
https://doi.org/10.1254/jpssuppl.wcp2018.0_po3-6-18
https://doi.org/10.1254/jpssuppl.wcp2018.0_po3-6-18
Autor:
Eijiro Jimi, Hiroshi Takeuchi, Akiko Mizokami, Takahito Otani, Satoru Mukai, Jing Gao, Masato Hirata, Tomoyo Kawakubo-Yasukochi
Publikováno v:
The Journal of endocrinology. 244(2)
Osteocalcin is a bone-derived hormone that in its uncarboxylated form (GluOC) plays an important role in glucose and energy metabolism by stimulating insulin secretion and pancreatic β-cell proliferation through its putative receptor GPRC6A. We prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1beb40b90a34eaf6f16cdacbd2008b2
https://pubmed.ncbi.nlm.nih.gov/31693486
https://pubmed.ncbi.nlm.nih.gov/31693486
Autor:
Takahito Otani, Tomoyo Kawakubo-Yasukochi, Masato Hirata, Akiko Mizokami, Tetsuichiro Inai, Hiroshi Takeuchi
Publikováno v:
Advances in Biological Regulation. 78:100752
Bone provides skeletal support and functions as an endocrine organ by producing osteocalcin, whose uncarboxylated form (GluOC) increases the metabolism of glucose and lipid by activating its putative G protein-coupled receptor (family C group 6 subty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e62bb6487845bdb3f46d5f254aa64b1
https://doi.org/10.1016/j.jbior.2020.100752
https://doi.org/10.1016/j.jbior.2020.100752
Autor:
Tetsuichiro Inai, Norio Kitagawa, Takahito Otani, Misaki Nikaido, Hiroshi Iida, Kayoko Ogata, Hisashi Anan
Publikováno v:
Histochemistry and cell biology. 151(5)
Keratinocytes in the oral mucosal epithelium, which is a non-keratinized stratified epithelium, are exposed to various stimuli from the oral cavity. JNK and p38 are stress-activated mitogen-activated protein kinases (MAPKs) that are phosphorylated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a997f930f3edda8c52e499f6d4f1c84
https://pubmed.ncbi.nlm.nih.gov/30284609
https://pubmed.ncbi.nlm.nih.gov/30284609
Autor:
Masato Hirata, Akiko Mizokami, Tetsuichiro Inai, Norio Kitagawa, Takahito Otani, Eijiro Jimi, Miho Matsuda, Hiroshi Takeuchi
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 9, Iss 12, Pp 1-17 (2018)
Cell Death and Disease, Vol 9, Iss 12, Pp 1-17 (2018)
The uncarboxylated form of osteocalcin (GluOC) regulates glucose and lipid metabolism in mice. We previously showed that low-dose (≤10 ng/ml) GluOC induces the expression of adiponectin and peroxisome proliferator-activated receptor γ (PPARγ) via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be9ecb295f7ed5efaecf58397604a63c
https://pubmed.ncbi.nlm.nih.gov/30546087
https://pubmed.ncbi.nlm.nih.gov/30546087