Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Takahito, Yamamoto"'
Publikováno v:
Journal of Infection and Chemotherapy. 16:49-52
We report a patient, a 52-year-old man from Laos, who had come to Japan at 30 years of age, but had maintained a habit of eating raw freshwater crabs. The patient visited a physician for left chest pain in January 2007. Infiltration and mass-like sha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb66789e36e1530725adca670791cd9f
https://doi.org/10.1007/s10156-009-0005-4
https://doi.org/10.1007/s10156-009-0005-4
Publikováno v:
Respiratory investigation. 55(2)
Background The efficacy of omalizumab, an anti-immunoglobulin E (IgE) antibody, has been studied in patients with severe bronchial asthma. We conducted a study to evaluate, on the basis of both objective and subjective measures, the efficacy of omali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e64e761a24f6c13ab2d5dd6e86f3bef
https://pubmed.ncbi.nlm.nih.gov/28274526
https://pubmed.ncbi.nlm.nih.gov/28274526
Publikováno v:
Current Drug Metabolism. 7:135-146
The purpose of this study was to propose a new method to predict in vivo drug-drug interactions (DDIs) for a high clearance drug from in vitro data. As the high clearance drug, NE-100 (N, N-dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4690fc84eb235cdf1ae409ba21f3438
https://doi.org/10.2174/138920006775541570
https://doi.org/10.2174/138920006775541570
Autor:
Huanmin Tang, Koichi Yamanishi, Yasuko Mori, Tomohiko Sadaoka, Yongmei Li, Takahito Yamamoto, Honglan Huang
Publikováno v:
Journal of General Virology. 87:277-285
In this study, the role of cholesterol in the envelope of human herpesvirus 6 (HHV-6) was examined by using methyl-β-cyclodextrin (MβCD) depletion. When cholesterol was removed from HHV-6 virions with MβCD, infectivity was abolished, but it could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c58728887b4c4fc0dd8b78b41ee9c20
https://doi.org/10.1099/vir.0.81551-0
https://doi.org/10.1099/vir.0.81551-0
Autor:
Yoshiro Kohno, Naoko Hagima, Kiyoshi Nagata, Takahito Yamamoto, Yasushi Yamazoe, Masato Nakamura
Publikováno v:
Xenobiotica. 34:687-703
It has previously been reported that N,N-dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]-ethylamine monohydrochloride (NE-100) was predominantly metabolized by cytochrome P450 (CYP) 2D6 in human liver microsomes (HLM). In the present study, the contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::849c9a84c7f076be82b637e809ffd017
https://doi.org/10.1080/00498250412331281070
https://doi.org/10.1080/00498250412331281070
Autor:
Kiyoshi Nagata, Masato Nakamura, Yasushi Yamazoe, Takahito Yamamoto, Naoko Hagima, Yoshiro Kohno
Publikováno v:
Drug Metabolism and Disposition. 31:60-66
N,N-Dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine monohydrochloride (NE-100) has been developed to treat subjects with schizophrenia. This drug is mainly excreted in the form of oxidative metabolites. In the present study, identification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db2e9d6e68446abec34186802c78f10
https://doi.org/10.1124/dmd.31.1.60
https://doi.org/10.1124/dmd.31.1.60
Autor:
Naoko Hagima, Yasushi Yamazoe, Kiyoshi Nagata, Yoshiro Kohno, Junichi Yamaguchi, Misako Fukasawa, Takahito Yamamoto, Masato Nakamura
Publikováno v:
Drug Metabolism and Pharmacokinetics. 18:173-185
Summary: In the present study, human cytochrome P450 (CYP) forms involved in producing the primary metabolites of NE-100 were identified. Major metabolites of NE-100 in human liver microsomes (HLM) were N -depropylation of NE-100 (NE-098), p -hydroxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d78408bacd5ae17b3882661cb03d70f2
https://doi.org/10.2133/dmpk.18.173
https://doi.org/10.2133/dmpk.18.173
Publikováno v:
Drug Metabolism and Pharmacokinetics. 17:437-448
Summary: Using a microtiter plate (MTP) assay consists of recombinant cytochromes P450 and fluorescent probes, we evaluated inhibitory effects of commercially available model-compounds, 18 typical substrates and 8 selective inhibitors, on nine cytoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8adaf0e38c377795915d5c94098d238a
https://doi.org/10.2133/dmpk.17.437
https://doi.org/10.2133/dmpk.17.437
Autor:
Satoshi, FUKUYO, Midori, KURIHARA, Ikuko, NAKASHINDEN, Keiji, KIMURA, Yoshihiro, IIJIMA, Yoichiro, KOBAYASHI, Tadashi, MASUZAWA, Satoko, YAMAMOTO, Maki, MORIMOTO, Tetsuya, KOUYAMA, Shingo, KOBAYASHI, Takahito, YAMAMOTO, Kazuharu, MIZUNO, Hiroyuki, MACHIDA
Publikováno v:
Proceedings of the NIPR Symposium on Polar Biology. 11:147-158
To determine the effect of wind on alpine plants, we set up five wind-shields (called WS) on a wind-blown alpine dwarf shrub community on Mount Kiso-komagatake (2956m), in the Central Japanese Alps, in June 1996. Air temperature at vegetation height,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::847b4a5f95db97482ed21ee03fdc968b
http://id.nii.ac.jp/1291/00005373/
http://id.nii.ac.jp/1291/00005373/
Autor:
Ikuko, NAKASHINDEN, Tadashi, MASUZAWA, Satoshi, FUKUYO, Keiji, KIMURA, Satoko, YAMAMOTO, Yoshihiro, IIJIMA, Kazuharu, MIZUNO, Shingo, KOBAYASHI, Takahito, YAMAMOTO, Hiroyuki, MACHIDA, Sadao, TAKAOKA
Publikováno v:
Proceedings of the NIPR Symposium on Polar Biology. 10:196-204
To predict the influence of global warming on high-mountain plants, we have started an experiment on Mt. Kisokomagatake (2956 m), the Central Japanese Alps, using the ITEX (International Tundra Experiment) method. Four small greenhouses (OTC: open-to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::70c07b30f740533a2ce74d5a90c04b53
http://id.nii.ac.jp/1291/00005351/
http://id.nii.ac.jp/1291/00005351/