Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Takahisa, Furukawa"'
Autor:
Rumi Kawashima, Kenji Matsushita, Kenji Mandai, Yuko Sugita, Tomohiko Maruo, Kiyohito Mizutani, Yoshihiro Midoh, Akiko Oguchi, Yasuhiro Murakawa, Kazuki Kuniyoshi, Ryohei Sato, Takahisa Furukawa, Kohji Nishida, Yoshimi Takai
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109577- (2024)
Summary: In vertebrates, retinal neural circuitry for visual perception is organized in specific layers. The outer plexiform layer is the first synaptic region in the visual pathway, where photoreceptor synaptic terminals connect with bipolar and hor
Externí odkaz:
https://doaj.org/article/2d2e6e92c3ed415b836cfa08d982c830
Autor:
Leah Rie Varner, Taro Chaya, Yamato Maeda, Ryotaro Tsutsumi, Shanshan Zhou, Toshinori Tsujii, Daisuke Okuzaki, Takahisa Furukawa
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109380- (2024)
Summary: Primary and secondary cone photoreceptor death in retinal degenerative diseases, including age-related macular degeneration (AMD) and retinitis pigmentosa (RP), leads to severe visual impairment and blindness. Although the cone photoreceptor
Externí odkaz:
https://doaj.org/article/e04d8c62e8454be3b5897b75b33ccd5b
Autor:
Shun Kubo, Haruka Yamamoto, Naoko Kajimura, Yoshihiro Omori, Yamato Maeda, Taro Chaya, Takahisa Furukawa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Establishing correct neuronal cell identity is essential to build intricate neural tissue architecture and acquire precise neural function during vertebrate development. While it is known that transcription factors play important roles in re
Externí odkaz:
https://doaj.org/article/ff2fda7fd48f4509a217d5b5e5305247
Autor:
Takefumi Sugiyama, Haruka Yamamoto, Tetsuo Kon, Taro Chaya, Yoshihiro Omori, Yutaka Suzuki, Kentaro Abe, Dai Watanabe, Takahisa Furukawa
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract The fovea is a pit formed in the center of the retina that enables high-acuity vision in certain vertebrate species. While formation of the fovea fascinates many researchers, the molecular mechanisms underlying foveal development are poorly
Externí odkaz:
https://doaj.org/article/c2dc0014cf1b47188cc42860b4fdf674
Autor:
Tetsuo Kon, Takahisa Furukawa
Publikováno v:
FEBS Open Bio, Vol 10, Iss 4, Pp 657-673 (2020)
Rax is one of the key transcription factors crucial for vertebrate eye development. In this study, we conducted comprehensive evolutionary analysis of Rax. We found that Bilateria and Cnidaria possess Rax, but Placozoa, Porifera, and Ctenophora do no
Externí odkaz:
https://doaj.org/article/161a1af93e854d3a8ec9c108d05472d9
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
The decline in visual function due to normal aging impacts various aspects of our daily lives. Previous reports suggest that the aging retina exhibits mislocalization of photoreceptor terminals and reduced amplitudes of scotopic and photopic electror
Externí odkaz:
https://doaj.org/article/d26e39786a0b44438b6049d47535ebb5
Publikováno v:
Cell Reports, Vol 30, Iss 3, Pp 658-671.e5 (2020)
Summary: Otx family homeoproteins Otx2 and Crx are expressed in photoreceptor precursor cells and bind to the common DNA-binding consensus sequence, but these two proteins have distinct functions in retinal development. To examine the functional subs
Externí odkaz:
https://doaj.org/article/1ff8874681a64f66bf3e728744d50a7f
Autor:
Akiko Ueno, Yoshihiro Omori, Yuko Sugita, Satoshi Watanabe, Taro Chaya, Takashi Kozuka, Tetsuo Kon, Satoyo Yoshida, Kenji Matsushita, Ryusuke Kuwahara, Naoko Kajimura, Yasushi Okada, Takahisa Furukawa
Publikováno v:
Cell Reports, Vol 22, Iss 13, Pp 3548-3561 (2018)
Summary: In the vertebrate retina, cone photoreceptors play crucial roles in photopic vision by transmitting light-evoked signals to ON- and/or OFF-bipolar cells. However, the mechanisms underlying selective synapse formation in the cone photorecepto
Externí odkaz:
https://doaj.org/article/d0527a428b204301a31f9ffba765da04
Autor:
Yuko, Sugita, Takahisa, Furukawa
Publikováno v:
Neuroscience. 501:42-51
In general, catechins contained in green tea are believed to have positive effects on the human body and mental health. The intake of epigallocatechin gallate (EGCG), a major polyphenol in green tea, is known to be effective for retinal protection; h
Autor:
Taro Chaya, Akihiro Matsumoto, Yuko Sugita, Satoshi Watanabe, Ryusuke Kuwahara, Masao Tachibana, Takahisa Furukawa
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract In the retinal circuit, environmental light signals are converted into electrical signals that can be decoded properly by the brain. At the first synapse of the visual system, information flow from photoreceptors to bipolar cells is modulate
Externí odkaz:
https://doaj.org/article/2d8538dcb7834fdaa45358c1dcf59fe0