Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Takahiro Umehara"'
Autor:
Satoshi Kimura, Hiroaki Sato, Shohei Shimajiri, Takahiro Umehara, Hirotsugu Noguchi, Daisuke Niino, Toshiyuki Nakayama
Publikováno v:
Heliyon, Vol 9, Iss 10, Pp e20791- (2023)
Background: Acute aortic dissection has a high mortality rate, especially for Stanford type A with a dissected ascending aorta. Cardiac tamponade is one of the most common complications of acute type A aortic dissection (ATAAD) and can cause death. H
Externí odkaz:
https://doaj.org/article/25572a17f74b4547b6488f154447af39
Autor:
Keita Shingu, Takehiko Murase, Takuma Yamamoto, Yuki Abe, Yoriko Shinba, Masahide Mitsuma, Takahiro Umehara, Hiromi Yamashita, Kazuya Ikematsu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract In sudden unexpected death in infancy cases, postmortem genetic analysis with next-generation sequencing potentially can extract candidate genes associated with sudden death. However, it is difficult to accurately interpret the clinically si
Externí odkaz:
https://doaj.org/article/7c7c566a7d5e473b91676776584a8379
Autor:
Takahiro Umehara, Ryoichi Mori, Kimberly A. Mace, Katsumi Tanaka, Noriho Sakamoto, Kazuya Ikematsu, Hiroaki Sato
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3129 (2022)
Diabetes is known to delay wound healing, and this delay is attributed to prolonged inflammation. We found that microRNAs (miRNAs) might be involved in the dysfunction of diabetic-derived neutrophils, and dynamics of neutrophil and chronic inflammati
Externí odkaz:
https://doaj.org/article/e12ed60c380a495aaebf9547645b5ed3
Autor:
Takuma Yamamoto, Makoto Otsu, Takashi Okumura, Yumi Horie, Yasuharu Ueno, Hideki Taniguchi, Manami Ohtaka, Mahito Nakanishi, Yuki Abe, Takehiko Murase, Takahiro Umehara, Kazuya Ikematsu
Publikováno v:
Stem Cell Research, Vol 39, Iss , Pp - (2019)
We established three iPSC lines from postmortem-cultured fibroblasts derived following the sudden unexpected death of an 8-year-old girl with Lennox-Gastaut syndrome, who turned out to have the R551H-mutant STXBP1 gene. These iPSC clones showed pluri
Externí odkaz:
https://doaj.org/article/c5161fae74104a45a6719e82756dd65f
Autor:
Takuma Yamamoto, Hiroyuki Mishima, Hajime Mizukami, Yuki Fukahori, Takahiro Umehara, Takehiko Murase, Masamune Kobayashi, Shinjiro Mori, Tomonori Nagai, Tatsushige Fukunaga, Seiji Yamaguchi, Koh-ichiro Yoshiura, Kazuya Ikematsu
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 5, Iss C, Pp 26-32 (2015)
The recent introduction of metabolic autopsy in the field of forensic science has made it possible to detect hidden inherited metabolic diseases. Since the next generation sequencing (NGS) has recently become available for use in postmortem examinati
Externí odkaz:
https://doaj.org/article/f06cea9104c14fbcb7e234bf5a6a64e5
Autor:
Maiko deKerckhove, Katsuya Tanaka, Takahiro Umehara, Momoko Okamoto, Sotaro Kanematsu, Hiroko Hayashi, Hiroki Yano, Soushi Nishiura, Shiho Tooyama, Yutaka Matsubayashi, Toshimitsu Komatsu, Seongjoon Park, Yuka Okada, Rina Takahashi, Yayoi Kawano, Takehisa Hanawa, Keisuke Iwasaki, Tadashige Nozaki, Hidetaka Torigoe, Kazuya Ikematsu, Yutaka Suzuki, Katsumi Tanaka, Paul Martin, Isao Shimokawa, Ryoichi Mori
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 10, Pp n/a-n/a (2018)
Abstract Argonaute 2 bound mature microRNA (Ago2‐miRNA) complexes are key regulators of the wound inflammatory response and function in the translational processing of target mRNAs. In this study, we identified four wound inflammation‐related Ago
Externí odkaz:
https://doaj.org/article/5d5fcb93f7564cd5a95e07278a823ab0
Publikováno v:
Case Reports in Infectious Diseases, Vol 2015 (2015)
More people are keeping pets in their homes but may not be sufficiently aware of the potential danger from infections. We report an autopsy case of a 57-year-old man affected by cirrhosis. Septic shock with Pasteurella multocida pneumonia was the cau
Externí odkaz:
https://doaj.org/article/8860e410426d4cdab6a0bc9910a6de3c
Autor:
Takahiro Umehara, Ryoichi Mori, Takehiko Murase, Toshiko Tanaka, Kentaro Kasai, Kazuya Ikematsu, Hiroaki Sato
Publikováno v:
Legal medicine (Tokyo, Japan). 59
Forensic diagnosis of fatal hypothermia is considered difficult because no specific findings, such as molecular markers, have been identified. Therefore, determining the molecular mechanism in hypothermia and identifying novel molecular markers to as
Autor:
Takahiro Umehara, Kazuya Ikematsu, Hiromi Yamashita, Yuki Abe, Hisayoshi Kondo, Takehiko Murase, Yoriko Shinba, Masahide Mitsuma, Keita Shingu
Publikováno v:
Legal medicine (Tokyo, Japan). 54
The goal of this pilot study was to develop an age-estimation formula and assess its effectiveness after evaluating individual intraoral findings. A total of 198 Japanese adults were included, and intraoral findings were collected from the corpses. T
Autor:
Kimberly A. Mace, Lale Gungordu, John R. Grainger, Takahiro Umehara, Tanja Torbica, Salma Alrdahe, Kelly Wemyss, Kate Wicks
Publikováno v:
Torbica, T, Wicks, K, Umehara, T, Gungordu, L, Alrdahe, S, Wemyss, K, Grainger, J & Mace, K 2019, ' Chronic inflammation in response to injury: retention of myeloid cells in injured tissue is driven by myeloid cell-intrinsic factors ', The Journal of Investigative Dermatology . https://doi.org/10.1016/j.jid.2018.12.030
Chronic inflammation is a hallmark of impaired healing in a plethora of tissues, including skin, and is associated with aging and diseases such as diabetes. Diabetic chronic skin wounds are characterized by excessive myeloid cells that display an abe