Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Takahiro Tsuno"'
Autor:
Junko Nishida, Takahiro Tsuno, Shigeharu G. Yabe, Tatsuya Kin, Satsuki Fukuda, Fujie Takeda, Jun Shirakawa, Hitoshi Okochi
Publikováno v:
Endocrine Journal, Vol 71, Iss 3, Pp 253-264 (2023)
Maintenance of islet function after in vitro culture is crucial for both transplantation and research. Here we evaluated the effects of encapsulation in alginate fiber on the function of human islets which were distributed by the Alberta Islet Distri
Externí odkaz:
https://doaj.org/article/17d1b3ba3e4c4e2ebeddff52c66c992b
Autor:
Yu Togashi, Daisuke Miyashita, Takahiro Tsuno, Ryota Inoue, Tomoko Okuyama, Mayu Kyohara, Kuniyuki Nishiyama, Masanori Arai, Kenta Kanematsu, Soichiro Kanataki, Yasuo Terauchi, Jun Shirakawa
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 11, Pp 1861-1872 (2022)
Abstract Aims/Introduction This study aimed to clarify the nature of the relationship between the abdominal aortic calcification (AAC) grade and the presence of cardiovascular diseases, and determine factors related to AAC grade in people with type 2
Externí odkaz:
https://doaj.org/article/e59f7325f10a4e7e9c8b470c89defc7a
Autor:
Jun Shirakawa, Yu Togashi, Giorgio Basile, Tomoko Okuyama, Ryota Inoue, Megan Fernandez, Mayu Kyohara, Dario F. De Jesus, Nozomi Goto, Wei Zhang, Takahiro Tsuno, Tatsuya Kin, Hui Pan, Jonathan M. Dreyfuss, A.M. James Shapiro, Peng Yi, Yasuo Terauchi, Rohit N. Kulkarni
Publikováno v:
Cell Reports, Vol 41, Iss 1, Pp 111436- (2022)
Summary: Prevention or amelioration of declining β cell mass is a potential strategy to cure diabetes. Here, we report the pathways utilized by β cells to robustly replicate in response to acute insulin resistance induced by S961, a pharmacological
Externí odkaz:
https://doaj.org/article/3143a9f198114e48a593ab4fa7acda69
Autor:
Ryota Inoue, Takahiro Tsuno, Yu Togashi, Tomoko Okuyama, Aoi Sato, Kuniyuki Nishiyama, Mayu Kyohara, Jinghe Li, Setsuko Fukushima, Tatsuya Kin, Daisuke Miyashita, Yusuke Shiba, Yoshitoshi Atobe, Hiroshi Kiyonari, Kana Bando, A.M. James Shapiro, Kengo Funakoshi, Rohit N. Kulkarni, Yasuo Terauchi, Jun Shirakawa
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104603- (2022)
Summary: Uncoupling protein 2 (UCP2), a mitochondrial protein, is known to be upregulated in pancreatic islets of patients with type 2 diabetes (T2DM); however, the pathological significance of this increase in UCP2 expression is unclear. In this stu
Externí odkaz:
https://doaj.org/article/749f21feddc94cc29bd880275707990e
Autor:
Mayu Kyohara, Daisuke Miyashita, Ryota Inoue, Kuniyuki Nishiyama, Takahiro Tsuno, Tomoko Okuyama, Yu Togashi, Yasuo Terauchi, Jun Shirakawa
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0276915 (2022)
Plasma and liver SerpinB1 levels are elevated in mice with insulin resistance and promote β-cell proliferation in human islets. We measured serum SerpinB1 levels in Japanese subjects with or without type 2 diabetes (T2DM). We enrolled 12 normal gluc
Externí odkaz:
https://doaj.org/article/cfa0caa090024e18b76b70c9cbb9465b
Autor:
Junko Nishida, Takahiro Tsuno, Yabe, Shigeharu G., Tatsuya Kin, Satsuki Fukuda, Fujie Takeda, Jun Shirakawa, Hitoshi Okochi
Publikováno v:
Endocrine Journal; 2024, Vol. 71 Issue 3, p253-264, 12p
Autor:
Masanori Arai, Takahiro Tsuno, Hiromi Konishi, Kuniyuki Nishiyama, Yasuo Terauchi, Ryota Inoue, Jun Shirakawa
Publikováno v:
Thyroid.
Autor:
Jinghe Li, Ryota Inoue, Ryoichi Akamatsu, Masanori Arai, Sakiko Terui, Yasuo Terauchi, Mayu Kyohara, Tomoko Okuyama, Takahiro Tsuno, Jun Shirakawa, Daisuke Miyashita, Yu Togashi
Publikováno v:
Diabetes Therapy
Introduction Dulaglutide is a long-acting glucagon-like peptide 1 receptor agonist that is administered once weekly for the treatment of type 2 diabetes. However, the immediate glucose-lowering effect of dulaglutide after the first administration and
Autor:
Daisuke Miyashita, Ryota Inoue, Takahiro Tsuno, Tomoko Okuyama, Mayu Kyohara, Chigusa Nakahashi-Oda, Kuniyuki Nishiyama, Setsuko Fukushima, Yutaro Inada, Yu Togashi, Akira Shibuya, Yasuo Terauchi, Jun Shirakawa
Publikováno v:
iScience. 25(12)
Obesity and diabetes are independent risk factors for death during sepsis. S100A8, an alarmin, is related to inflammation, obesity, and diabetes. Here, we examine the role of S100A8 in sepsis of obesity and diabetes models. Injection of S100A8 prolon
Autor:
Daisuke Miyashita, Ryota Inoue, Takahiro Tsuno, Tomoko Okuyama, Mayu Kyohara, Chigusa Nakahashi-Oda, Kuniyuki Nishiyama, Yutaro Inada, Yu Togashi, Akira Shibuya, Yasuhiro Terauchi, Jun Shirakawa
Publikováno v:
SSRN Electronic Journal.