Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Takahiro Okuno"'
Autor:
Kosuke Tsuda, Daichi Maeda, Yumiko Kanzaki, Kazushi Sakane, Takahiro Okuno, Sayuri Nakayama, Daisuke Tokura, Hitomi Hasegawa, Masaaki Hoshiga
Publikováno v:
ESC Heart Failure, Vol 10, Iss 3, Pp 1726-1734 (2023)
Abstract Aims Worsening renal function (WRF) often develops during heart failure (HF) treatment. However, prognostic implications of WRF in acute HF remain controversial, and risk stratification of WRF is challenging. Although the fibrosis‐4 index
Externí odkaz:
https://doaj.org/article/b9b2a86321f14c13bc1b8af867205c1a
Autor:
Yasuhiro Fukui, Akihiro Murata, Sadatoshi Shimizu, Kayo Sai, Takuma Okada, Tetsuzo Tashima, Shintaro Kodai, Akishige Kanazawa, Takahiro Okuno
Publikováno v:
Surgical Case Reports, Vol 8, Iss 1, Pp 1-6 (2022)
Abstract Background Mucinous cystic neoplasm of the liver (MCN-L) is a rare cystic tumor as defined by the 2010 World Health Organization classification. MCN-L usually does not communicate with or grow into the bile duct. Herein, we present a rare ca
Externí odkaz:
https://doaj.org/article/30591f6463674ad4a7f8bb7c80c02903
Autor:
Daichi Maeda, Yumiko Kanzaki, Kazushi Sakane, Kosuke Tsuda, Kanako Akamatsu, Ryoto Hourai, Takahiro Okuno, Daisuke Tokura, Sayuri Nakayama, Hitomi Hasegawa, Hideaki Morita, Takahide Ito, Masaaki Hoshiga
Publikováno v:
ESC Heart Failure, Vol 9, Iss 2, Pp 1380-1387 (2022)
Abstract Aims Recently, liver fibrosis markers, such as the fibrosis‐4 index (FIB‐4), have been shown to be associated with prognosis in patients with heart failure. The fibrosis‐5 (FIB‐5) index, which assesses albumin, alkaline phosphatase,
Externí odkaz:
https://doaj.org/article/7b888833f0a543848a0ce9d66b2e8c90
Autor:
Keiji Konishi, Hidenori Nakagawa, Akio Nakahira, Takahiro Okuno, Takeshi Inoue, Michinori Shirano
Publikováno v:
AIDS Research and Therapy, Vol 18, Iss 1, Pp 1-5 (2021)
Abstract Background Disseminated Mycobacterium avium complex infection is an important indicator of acquired immunodeficiency syndrome (AIDS) in patients with advanced human immunodeficiency virus (HIV) infection. Effective antiretroviral therapy has
Externí odkaz:
https://doaj.org/article/77eb5c8c1c704cb08a224fde7e098805
Autor:
Anna Kakehashi, Shugo Suzuki, Naomi Ishii, Takahiro Okuno, Yuko Kuwae, Masaki Fujioka, Min Gi, Vasily Stefanov, Hideki Wanibuchi
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7746 (2020)
To uncover mechanisms and explore novel biomarkers of obesity, type 2 diabetes (T2DM) and nonalcoholic steatohepatitis (NASH)-associated hepatocarcinogenesis, cellular and molecular alterations in the liver, and hepatocellular carcinomas (HCCs) were
Externí odkaz:
https://doaj.org/article/ca0e0bc47df246ba95e411f392474071
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 8, p 1801 (2017)
The role of deficiency of oxoguanine glycosylase 1 (Ogg1) Mmh homolog, a repair enzyme of the 8-hydroxy-2’-deoxyguanosine (8-OHdG) residue in DNA, was investigated using the multiorgan carcinogenesis bioassay in mice. A total of 80 male and female
Externí odkaz:
https://doaj.org/article/64b8475f0efe4731b755748d75bd54d8
Autor:
Anna Kakehashi, Vasily E. Stefanov, Naomi Ishii, Takahiro Okuno, Hideki Fujii, Kazuaki Kawai, Norifumi Kawada, Hideki Wanibuchi
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 2, p 434 (2017)
To uncover mechanisms of nonalcoholic steatohepatitis (NASH) associated hepatocarcinogenesis, we compared the proteomes of human NASH-associated liver biopsies, resected hepatocellular carcinomas (HCCs) and HCCs of HCV+ patients with normal liver tis
Externí odkaz:
https://doaj.org/article/a092581cc6f249dabc6a1eaaf0afbb9c
Autor:
Anna Kakehashi, Midori Yoshida, Yoshiyuki Tago, Naomi Ishii, Takahiro Okuno, Min Gi, Hideki Wanibuchi
Publikováno v:
Toxins, Vol 8, Iss 11, p 275 (2016)
Pueraria mirifica (PM), a plant whose dried and powdered tuberous roots are now widely used in rejuvenating preparations to promote youthfulness in both men and women, may have major estrogenic influence. In this study, we investigated modifying effe
Externí odkaz:
https://doaj.org/article/fe48860f7dc74ec4b2d2f0d3c2165401
Autor:
Daichi, Maeda, Yumiko, Kanzaki, Kazushi, Sakane, Kosuke, Tsuda, Kanako, Akamatsu, Ryoto, Hourai, Takahiro, Okuno, Daisuke, Tokura, Hitomi, Hasegawa, Kenta, Sakaguchi, Takahide, Ito, Masaaki, Hoshiga
Publikováno v:
International Heart Journal. 63:1121-1127
The fibrosis-4 index, albumin-bilirubin score and neutrophil-lymphocyte ratio are all prognostic markers in patients with heart failure. Recently, the FAN score, which includes all 3 of these markers, was developed as a useful risk stratification too
Autor:
Keiji Tasaka, Hiroo Ueno, Kai Yamasaki, Takahiro Okuno, Tomoya Isobe, Shunsuke Kimura, Katsutsugu Umeda, Junichi Hara, Seishi Ogawa, Junko Takita
Publikováno v:
Cancer Science. 113(4):1535-1541
Neuroblastoma (NB) and pheochromocytoma (PCC) are derived from neural crest cells (NCCs); however, composite tumors with NB and PCC are rare, and their underlying molecular mechanisms remain unknown. To address this issue, we performed exome and tran