Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Takahiro OKADA"'
Autor:
Naoki Oshima, Yoshiyuki Mishima, Kotaro Shibagaki, Kousaku Kawashima, Norihisa Ishimura, Fumiyoshi Ikejiri, Chie Onishi, Takahiro Okada, Masaya Inoue, Ichiro Moriyama, Junji Suzumiya, Yoshikazu Kinoshita, Shunji Ishihara
Publikováno v:
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-7 (2021)
Abstract Background Dasatinib is a second-generation tyrosine kinase inhibitor (TKI) developed for treatment of patients with chronic myeloid leukemia (CML). The drug has been shown to act as a potent multikinase inhibitor by blocking not only the BC
Externí odkaz:
https://doaj.org/article/852456db15cd41d6b298d2b41507975a
Autor:
Suresh Awale, Hayato Baba, Nguyen Duy Phan, Min Jo Kim, Juthamart Maneenet, Koichi Sawaki, Mitsuro Kanda, Tomoyuki Okumura, Tsutomu Fujii, Takuya Okada, Takahiro Maruyama, Takahiro Okada, Naoki Toyooka
Publikováno v:
Journal of Medicinal Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::883f9193f74b1cde09ee699201e0c65a
https://doi.org/10.1021/acs.jmedchem.3c00394
https://doi.org/10.1021/acs.jmedchem.3c00394
Autor:
Kosuke Sakurai, Noriko Kohyama, Takahiro Okada, Yusuke Miwa, Miki Takenaka, Mari Kogo, Takashi Yamaguchi, Tatsuya Kurihara
Publikováno v:
Internal Medicine
Objective We aimed to develop a scoring model to predict a low disease activity (LDA) in elderly rheumatoid arthritis (RA) patients initially treated with biological disease-modifying antirheumatic drugs (bDMARDs). Methods This retrospective cohort s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af465b461498849a6e87cac026227d5
https://doi.org/10.2169/internalmedicine.6251-20
https://doi.org/10.2169/internalmedicine.6251-20
Autor:
Urano Takeshi, Junji Suzumiya, Ritsuro Suzuki, Chinadol Wanitpongpun, Yoshio Honma, Takahiro Okada
Publikováno v:
Leukemia & Lymphoma. 62:1585-1596
Although romidepsin as monotherapy appears to be useful for treating T-cell lymphoma, combined chemotherapy with other therapeutic agents is required for improvement of the treatment outcome. To establish safer and more effective regimens, systematic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30dbe029a1320eff4516cb82c2e8871d
https://doi.org/10.1080/10428194.2021.1876857
https://doi.org/10.1080/10428194.2021.1876857
Autor:
Fumimasa Takahashi, Takaaki Miyake, Tsutomu Takahashi, Riruke Maruyama, Shunsuke Ito, Masaya Inoue, Ayumi Fujimoto, Koichi Ohshima, Takahiro Okada, Ritsuro Suzuki, Fumiyoshi Ikejiri, Yusuke Okada, Junji Suzumiya, Shinichiro Matsuda, Fumiko Arakawa
Publikováno v:
American Journal of Clinical Pathology. 155:308-317
Objectives We report a rare case of B-lymphoblastic lymphoma (B-LBL) and low-grade follicular lymphoma (FL) identified concurrently in biopsies from different sites at the initial diagnosis in a 39-year-old man. The clonal relationship between the 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77154ac6ed38a163b84cdf545f465d77
https://doi.org/10.1093/ajcp/aqaa126
https://doi.org/10.1093/ajcp/aqaa126
Autor:
Daichi Hayakawa, Noriki Kutsumura, Yukiko Ishikawa, Yoko Irukayama-Tomobe, Tsuyoshi Saitoh, Naoshi Yamamoto, Takahiro Okada, Hiroaki Gouda, Sayaka Ohrui, Masashi Yanagisawa, Yurie Watanabe, Hiroshi Nagase, Yasuyuki Nagumo, Yasuhiro Ogawa
Publikováno v:
Bioorganic & Medicinal Chemistry. 27:1747-1758
Morphinan derivatives lacking the 4,5-epoxy ring were synthesized to examine the participation of the 14-OH group, the 3-OMe group, and the aromaticity of the A-ring in the activity and selectivity for the orexin 1 receptor (OX1R). The assay results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb2366a4c1289deaee4efa1703d789b
https://doi.org/10.1016/j.bmc.2019.03.010
https://doi.org/10.1016/j.bmc.2019.03.010
Autor:
Kosuke Sakurai, Takahiro Okada, Noriko Kohyama, Yusuke Miwa, Mari Kogo, Takashi Yamaguchi, Tatsuya Kurihara, Miki Takenaka
Publikováno v:
Clinical rheumatology. 40(7)
We investigated factors predicting the addition of disease-modifying antirheumatic drugs (DMARDs) after an initial methotrexate (MTX) monotherapy in rheumatoid arthritis (RA) patients to support an early decision on the DMARDs addition.This retrospec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e16b06d9848007f31d3a68e80b71e88
https://pubmed.ncbi.nlm.nih.gov/33483918
https://pubmed.ncbi.nlm.nih.gov/33483918
Publikováno v:
Synthesis. 50:4263-4269
A novel retro-ene reaction via a [4.4.3]propellane intermediate containing a quaternary ammonium linkage was developed. The feature of this acetic anhydride mediated rearrangement includes the elimination of an acetoxy group at the C14 position and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fae6ba250a8d98b37c840896d892c182
https://doi.org/10.1055/s-0036-1589138
https://doi.org/10.1055/s-0036-1589138
Autor:
Hideaki Fujii, Noriki Kutsumura, Satomi Imaide, Takahiro Okada, Tsuyoshi Saitoh, Hiroshi Nagase, Yukimasa Harada, Naoshi Yamamoto
Publikováno v:
Tetrahedron. 73:5751-5758
(–)-Galanthamine ( 4 ) was synthesized from naltrexone ( 1 ) in 18 steps with 3% total yield by overcoming many specific side reactions derived from the 4,5-epoxymorphinan skeleton. The key features are cleavage of the D-ring by the Hofmann elimina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fed2ae72d6de00434e5406eaa28b0a32
https://doi.org/10.1016/j.tet.2017.08.014
https://doi.org/10.1016/j.tet.2017.08.014
Autor:
Eiji Hayashi, Takahiro Okada
Publikováno v:
Proceedings of International Conference on Artificial Life and Robotics. 22:96-99
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae84cbddff7d015de8fb9703abf12d64
https://doi.org/10.5954/icarob.2017.gs6-3
https://doi.org/10.5954/icarob.2017.gs6-3