Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Takahiro Muraoka"'
Autor:
Takahiro Nakayama, Akash K. Singh, Toshiyuki Fukutomi, Noriyuki Uchida, Yasuo Terao, Hiroki Hamada, Takahiro Muraoka, Eswaramoorthy Muthusamy, Tapas K. Kundu, Kimio Akagawa
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114101- (2024)
Summary: Syntaxin-1A (stx1a) repression causes a neurodevelopmental disorder phenotype, low latent inhibition (LI) behavior, by disrupting 5-hydroxytryptaminergic (5-HTergic) systems. Herein, we discovered that lysine acetyltransferase (KAT) 3B incre
Externí odkaz:
https://doaj.org/article/7082df1e29b6458ba0cf338791935a20
Autor:
Atsuya Yaguchi, Mio Oshikawa, Go Watanabe, Hirotsugu Hiramatsu, Noriyuki Uchida, Chikako Hara, Naoko Kaneko, Kazunobu Sawamoto, Takahiro Muraoka, Itsuki Ajioka
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The extracellular matrix contributes to tissue regeneration by binding and releasing growth factors. Here the authors present the jigsaw-shaped self-assembling peptide JigSAP as an artificial ECM and show that VEGF-JigSAP has therapeutic effects on t
Externí odkaz:
https://doaj.org/article/ace4d5be898e4312b4bf35de4601f775
Publikováno v:
Biophysics and Physicobiology, Vol 19 (2022)
Externí odkaz:
https://doaj.org/article/545a6aa8d14b43a794f3e73875a01f7f
Autor:
Takahiro Muraoka, Daiki Noguchi, Rinshi S. Kasai, Kohei Sato, Ryo Sasaki, Kazuhito V. Tabata, Toru Ekimoto, Mitsunori Ikeguchi, Kiyoto Kamagata, Norihisa Hoshino, Hiroyuki Noji, Tomoyuki Akutagawa, Kazuaki Ichimura, Kazushi Kinbara
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Transmembrane proteins are important for cellular functions and synthetic analogues are of interest. Here the authors report on the design and testing of a synthetic multipass transmembrane channel which shows anisotropic responses to agonistic and a
Externí odkaz:
https://doaj.org/article/8d4b05d38a764d63897b3b2f6cc88bf5
Autor:
Yasuhito Yokoi, Yugo Kawabuchi, Abdullah Adham Zulmajdi, Reiji Tanaka, Toshiyuki Shibata, Takahiro Muraoka, Tetsushi Mori
Publikováno v:
Molecules, Vol 27, Iss 24, p 8944 (2022)
Approximately 30% or more of the total proteins annotated from sequenced bacteria genomes are annotated as hypothetical or uncharacterized proteins. However, elucidation on the function of these proteins is hindered by the lack of simple and rapid sc
Externí odkaz:
https://doaj.org/article/2a834f622e0e407ca0972b2ffbdcf8bd
Publikováno v:
ACS Omega, Vol 3, Iss 1, Pp 414-418 (2018)
Externí odkaz:
https://doaj.org/article/5ec3cca794db431c9e3df74483b396f9
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Conventionally, the delivery of biomolecules into bacteria for the generation of characterized or functional mutants has relied greatly on horizontal gene transfer techniques. However, the low compatibility of these techniques with novel or hard-to-t
Externí odkaz:
https://doaj.org/article/baf8ec71fe3c4881ae14f54016a61dfc
Publikováno v:
Molecules, Vol 26, Iss 4, p 879 (2021)
Oxidative protein folding is a biological process to obtain a native conformation of a protein through disulfide-bond formation between cysteine residues. In a cell, disulfide-catalysts such as protein disulfide isomerase promote the oxidative protei
Externí odkaz:
https://doaj.org/article/e3dec673a4154596aef5210e66455dd8
Autor:
Noriyuki Uchida, Takahiro Muraoka
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7577 (2020)
Peptide-based fibrous supramolecular assemblies represent an emerging class of biomaterials that can realize various bioactivities and structures. Recently, a variety of peptide fibers with attractive functions have been designed together with the di
Externí odkaz:
https://doaj.org/article/e33c2eb6df20416ebc2820c66fa61971
Autor:
Hisae Tateishi-Karimata, Tatsuya Ohyama, Takahiro Muraoka, Shigenori Tanaka, Kazushi Kinbara, Naoki Sugimoto
Publikováno v:
Molecules, Vol 25, Iss 3, p 705 (2020)
Methods for stabilizing G-quadruplex formation is a promising therapeutic approach for cancer treatment and other biomedical applications because stable G-quadruplexes efficiently inhibit biological reactions. Oligo and polyethylene glycols are promi
Externí odkaz:
https://doaj.org/article/f0bc9c3d319c4320a9d22e46476ccb04