Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Takahiro Miyawaki"'
Autor:
Tomoaki Kameda, Tadataka Kawakami, Takahiro Miyawaki, Takehiko Konno, Kohei Furuya, Shigeru Fujimoto, Shunichi Okada, Kumiko Miura
Publikováno v:
Rinsho shinkeigaku = Clinical neurology. 60(1)
Background Metabolic insult causing re-expression of old stroke (MICROS), one of the stroke mimics, is characterized by reappearance of impairment of past stroke and can be mistaken for a stroke recurrence. The aim of the present study was to identif
Autor:
Sean M.J. McBride, Eric Klann, Takahiro Miyawaki, Ali Sharma, R. Suzanne Zukin, Charles A. Hoeffer, Yukihiro Takayasu
Publikováno v:
The Journal of Neuroscience. 30:694-702
Fragile X syndrome, the most common form of inherited mental retardation and leading genetic cause of autism, is caused by transcriptional silencing of theFmr1gene. The fragile X mental retardation protein (FMRP), the gene product ofFmr1, is an RNA b
Autor:
Takahiro Miyawaki, Michael V. L. Bennett, R. Suzanne Zukin, Kyung-Min Noh, Toshihiro Mashiko, Luigi Formisano
Publikováno v:
Proceedings of the National Academy of Sciences. 104:4170-4175
Transient global ischemia is a neuronal insult that induces delayed, selective death of hippocampal CA1 pyramidal neurons. A mechanism underlying ischemia-induced cell death is activation of the gene silencing transcription factor REST (repressor ele
Autor:
Shimon Amemmiya, Yasuhiro Nishiyama, Satoshi Suda, Tatsuhiko Kanno, Yasuo Katayama, Masayuki Ueda, Takahiro Miyawaki, Tatsushi Kamiya, Hidenori Yokota, Kuniko Shimazaki, Kengo Kato, Masaru Okabe, Eiju Watanabe, Keiji Oguro
Publikováno v:
Nosotchu. 28:607-611
局所脳虚血急性期での骨髄間葉系幹細胞(MSC)の投与により,梗塞巣の縮小効果が報告されている.われわれは,SD系RATを用いて90分間の中大脳動脈脈閉塞(MCAO)モデルを作成し,3時間後に静脈内
Publikováno v:
Neuroscience Letters. 362:216-219
In normal gerbils, intracellular zinc ions ([Zn2+]i) and calcium ions ([Ca2+]i) accumulate in hippocampal CA1 neurons after global ischemia. We examined whether ischemic preconditioning modifies these changes in gerbil hippocampal slices. In normal s
Autor:
Toshihiro Mashiko, Dimitry Ofengeim, Takahiro Miyawaki, R. Suzanne Zukin, Richard J. Flannery, Kyung-Min Noh, Laura Bonanni, Michael V. L. Bennett, Sho Fujisawa, Elizabeth A. Jonas
Publikováno v:
Proceedings of the National Academy of Sciences. 108:16855-16857
Autor:
Katsuhiro Konno, Hiroshi Tsubokawa, Nobufumi Kawai, Takahiro Miyawaki, Toshio Masuzawa, Hidenori Yokota, Hitoshi Nakayama
Publikováno v:
Neuroscience Research. 41:365-371
We examined the effects of beta-pompilidotoxin (beta-PMTX), a neurotoxin derived from wasp venom, on synaptic transmission in the mammalian central nervous system (CNS). Using hippocampal slice preparations of rodents, we made both extracellular and
Publikováno v:
Japanese Journal of Neurosurgery. 10:409-413
Autor:
Keiji Oguro, Hidenori Yokota, Hiroshi Tsubokawa, Nobufumi Kawai, Takahiro Miyawaki, Hiroyuki Cho, Toshio Masuzawa
Publikováno v:
Neuroscience Research. 29:273-281
We studied N -methyl- d -aspartate (NMDA) receptor-mediated synaptic potentials in CA1 pyramidal neurons using hippocampal slices of gerbils after transient forebrain ischemia. In the presence of 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) and bicucu
Autor:
Michael V. L. Bennett, John M. Greally, Kyung-Min Noh, Antonia Follenzi, Rodoniki Athanasiadou, Takahiro Miyawaki, Jee Yeon Hwang, R. Suzanne Zukin
Publikováno v:
Proceedings of the National Academy of Sciences. 109
Dysregulation of the transcriptional repressor element-1 silencing transcription factor (REST)/neuron-restrictive silencer factor is important in a broad range of diseases, including cancer, diabetes, and heart disease. The role of REST-dependent epi