Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Takahiro Kochi"'
Autor:
Fumiaki Sato, Yoki Nakamura, Simeng Ma, Takahiro Kochi, Kazue Hisaoka-Nakashima, Dengli Wang, Keyue Liu, Hidenori Wake, Masahiro Nishibori, Norimitsu Morioka
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 145, Iss , Pp 112479- (2022)
Parkinson’s disease (PD) patients often complain of pain, but this problem has been neglected and is poorly understood. High mobility group box-1 (HMGB1), an alarmin/damage-associated molecular patterns protein, is increased in the cerebrospinal fl
Externí odkaz:
https://doaj.org/article/4efe221e41c54d65a4e1ceaa56261473
Autor:
Yohei Shirakami, Takayuki Nakanishi, Noritaka Ozawa, Takayasu Ideta, Takahiro Kochi, Masaya Kubota, Hiroyasu Sakai, Takashi Ibuka, Takuji Tanaka, Masahito Shimizu
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251942 (2021)
Prostaglandin E2 receptor EP4 is involved in inflammation and related tumorigenesis in the colorectum. This study aimed to investigate the chemopreventive ability of RQ-15986, a selective EP4 antagonist, in colitis-related colorectal tumorigenesis. M
Externí odkaz:
https://doaj.org/article/632ca27268e34ffbae3aa9cd0de6aa1e
Autor:
Takahiro Kochi, Yoki Nakamura, Simeng Ma, Kazue Hisaoka-Nakashima, Dengli Wang, Keyue Liu, Hidenori Wake, Masahiro Nishibori, Masahiro Irifune, Norimitsu Morioka
Publikováno v:
Molecules, Vol 26, Iss 7, p 2035 (2021)
Persistent pain following orofacial surgery is not uncommon. High mobility group box 1 (HMGB1), an alarmin, is released by peripheral immune cells following nerve injury and could be related to pain associated with trigeminal nerve injury. Distal inf
Externí odkaz:
https://doaj.org/article/d0d69cededf345dd94f0e214aaee24b1
Autor:
Takahiro Kochi, Masahito Shimizu, Yukari Totsuka, Yohei Shirakami, Takayuki Nakanishi, Tetsushi Watanabe, Takuji Tanaka, Hitoshi Nakagama, Keiji Wakabayashi, Hisataka Moriwaki
Publikováno v:
Toxicology Reports, Vol 1, Iss C, Pp 69-73 (2014)
The benzoazepinoqunolinone derivative, 5-amino-6-hydroxy-8H-benzo[6,7]azepino[5,4,3-de]quinolin-7-one (ABAQ), which is produced in a mixture of glucose and tryptophan incubated at 37 °C under physiological conditions in the presence or absence of hy
Externí odkaz:
https://doaj.org/article/a5b465d976624acea86af21890986951
Autor:
Tomohiko Ohno, Masahito Shimizu, Yohei Shirakami, Atsushi Baba, Takahiro Kochi, Masaya Kubota, Hisashi Tsurumi, Takuji Tanaka, Hisataka Moriwaki
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124081 (2015)
Obesity and related metabolic disorders, such as diabetes mellitus, raise the risk of liver carcinogenesis. Metformin, which is widely used in the treatment of diabetes, ameliorates insulin sensitivity. Metformin is also thought to have antineoplasti
Externí odkaz:
https://doaj.org/article/20544a2f08aa4db587e468f6d0ff41b7
Autor:
Junji Nagano, Masahito Shimizu, Takeshi Hara, Yohei Shirakami, Takahiro Kochi, Nobuhiko Nakamura, Hirofumi Ohtaki, Hiroyasu Ito, Takuji Tanaka, Hisashi Tsurumi, Kuniaki Saito, Mitsuru Seishima, Hisataka Moriwaki
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73404 (2013)
Hepatic immune regulation is associated with the progression from simple steatosis to non-alcoholic steatohepatitis, a severe condition of inflamed fatty liver. Indoleamine 2,3-dioxygenase (IDO), an intracellular enzyme that mediates the catabolism o
Externí odkaz:
https://doaj.org/article/8fa3ae3585844194ba1b716e06c3546c
Autor:
Mitsuru Okuno, Tsuyoshi Mukai, Keisuke Iwata, Naoki Watanabe, Takuji Tanaka, Taisei Iwasa, Kota Shimojo, Yosuke Ohashi, Akihiro Takagi, Yuki Ito, Ryuichi Tezuka, Shota Iwata, Yuhei Iwasa, Takahiro Kochi, Tomio Ogiso, Hideki Hayashi, Akihiko Sugiyama, Youichi Nishigaki, Eiichi Tomita
Publikováno v:
Cancers; Volume 14; Issue 11; Pages: 2701
The specimen collection and subsequent pathological diagnosis of malignant biliary stricture (MBS) are difficult. This study aimed to determine whether the cell block (CB) method using overnight-stored bile is useful in the diagnosis of MBS. This tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d40d0e8718f46c122c764d92622183
Autor:
Katsuhisa Toda, Kentaro Otsuji, Tatsuhiko Miyazaki, Naoki Katsumura, Masashi Aiba, Noriaki Nakamura, Takao Miwa, Masahito Shimizu, Takahiro Kochi
Publikováno v:
Journal of Rural Medicine : JRM
Liposarcoma is one of the most common types of soft tissue sarcomas and can develop at any site, although omental liposarcoma is extremely rare. Omental liposarcoma has a poor prognosis because the diagnosis is difficult, until it presents as a large
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9349f836fe7fd79177ced158f5275bf
http://europepmc.org/articles/PMC7110100
http://europepmc.org/articles/PMC7110100
Autor:
Shinji Unome, Kenji Imai, Koji Takai, Takao Miwa, Tatsunori Hanai, Yoichi Nishigaki, Hideki Hayashi, Takahiro Kochi, Shogo Shimizu, Junji Nagano, Soichi Iritani, Atsushi Suetsugu, Masahito Shimizu
Publikováno v:
Cancers; Volume 14; Issue 24; Pages: 6089
In this study, we aimed to evaluate the efficacy and safety of atezolizumab plus bevacizumab (Atez/Bev) treatment for unresectable hepatocellular carcinoma (HCC) and to analyze the factors affecting overall survival (OS). A total of 69 patients who r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8925cdbfd5c2f43047b824a45806f2
https://doi.org/10.3390/cancers14246089
https://doi.org/10.3390/cancers14246089
Autor:
Takahiro Kochi, Yoki Nakamura, Simeng Ma, Suzuna Uemoto, Kazue Hisaoka-Nakashima, Masahiro Irifune, Norimitsu Morioka
Publikováno v:
Behavioural brain research. 425
Post-traumatic trigeminal neuropathy (PTTN) is a chronic sensory disorder that afflicts patients with nerve injury caused by orofacial and dental surgery or cervicofacial trauma. Currently, effective treatment strategies for PTTN are lacking, and pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1fd8800da2b3ecbb282ba5ea04ea56f
https://pubmed.ncbi.nlm.nih.gov/35248649
https://pubmed.ncbi.nlm.nih.gov/35248649