Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Takahiro Kawamata"'
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Akademický článek
Pathological Complete Response after Immune-Checkpoint Inhibitor Followed by Salvage Surgery for Clinical Stage IV Pulmonary Adenocarcinoma with Continuous Low Neutrophil-to-Lymphocyte Ratio: A Case Report
Autor: Mitsunori Higuchi, Takahiro Kawamata, Ikuro Oshibe, Nobutoshi Soeta, Takuro Saito, Hiroshi Hojo, Yuki Matsumura, Hiroyuki Suzuki
Publikováno v: Case Reports in Oncology, Vol 14, Iss 2, Pp 1124-1133 (2021)
Immune-checkpoint inhibitors (ICIs) play a crucial role in the treatment of advanced nonsmall cell lung cancer (NSCLC); however, most patients fail this treatment after a limited period. We here report a patient with a pathological complete response
Externí odkaz: https://doaj.org/article/32e1aac5e0574eb18458fd3e44c20631
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Total Synthesis of Zaragozic Acid C: Implementation of Photochemical C(sp3)–H Acylation
Autor: Masayuki Inoue, Takahiro Kawamata, Masanori Nagatomo
Publikováno v: Journal of the American Chemical Society. 139:1814-1817
Zaragozic acid C (1) was isolated as a potent squalene synthase inhibitor. The 2,8-dioxabicyclo[3.2.1]octane core of 1 is decorated with the three hydroxycarbonyl (C3,4,5), two hydroxy (C4,7), one acyloxy (C6), and one alkyl (C1) groups. Installation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2f5e61aae49447b274249876528a64b0
https://doi.org/10.1021/jacs.6b13263
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Convergent Total Synthesis of Asimicin via Decarbonylative Radical Dimerization
Autor: Akinori Yamaguchi, Takahiro Kawamata, Masayuki Inoue, Masanori Nagatomo
Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany). 24(71)
Asimicin (1) exhibits potent antitumor activity and comprises a central C2 -symmetric bis-tetrahydrofuran and two aliphatic side-chains, one of which terminates with (S)-methyl-2(5H)-furanone. This work reports a convergent total synthesis of 1 in 17
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b405e3e0650f01e6d358a7849c53729
https://pubmed.ncbi.nlm.nih.gov/33586822
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Symmetry-Driven Strategy for the Assembly of the Core Tetracycle of (+)-Ryanodine: Synthetic Utility of a Cobalt-Catalyzed Olefin Oxidation and α-Alkoxy Bridgehead Radical Reaction
Autor: Takahiro Kawamata, Masayuki Inoue, Masanori Nagatomo, Kengo Masuda, Masaki Koshimizu, Koji Hagiwara, Daisuke Urabe, Yuki Matsui
Publikováno v: Chemistry - A European Journal. 22:222-229
Ryanodine (1) is a potent modulator of intracellular calcium release channels, designated as ryanodine receptors. The exceptionally complex molecular architecture of 1 comprises a highly oxygenated pentacyclic system with eleven contiguous stereogeni
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a00d9f93563ff4917abcad0f9150a2
https://doi.org/10.1002/chem.201503640
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6
Total Synthesis of Zaragozic Acid C: Implementation of Photochemical C(sp
Autor: Takahiro, Kawamata, Masanori, Nagatomo, Masayuki, Inoue
Publikováno v: Journal of the American Chemical Society. 139(5)
Zaragozic acid C (1) was isolated as a potent squalene synthase inhibitor. The 2,8-dioxabicyclo[3.2.1]octane core of 1 is decorated with the three hydroxycarbonyl (C3,4,5), two hydroxy (C4,7), one acyloxy (C6), and one alkyl (C1) groups. Installation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e29511bfe50abea2a86c6d252f87e72e
https://pubmed.ncbi.nlm.nih.gov/28092952
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ChemInform Abstract: Symmetry-Driven Strategy for the Assembly of the Core Tetracycle of (+)-Ryanodine: Synthetic Utility of a Cobalt-Catalyzed Olefin Oxidation and α-Alkoxy Bridgehead Radical Reaction
Autor: Masayuki Inoue, Takahiro Kawamata, Koji Hagiwara, Masanori Nagatomo, Yuki Matsui, Masaki Koshimizu, Daisuke Urabe, Kengo Masuda
Publikováno v: ChemInform. 47
Ryanodine (1) is a potent modulator of intracellular calcium release channels, designated as ryanodine receptors. The exceptionally complex molecular architecture of 1 comprises a highly oxygenated pentacyclic system with eleven contiguous stereogeni
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::66eccf417f2f154fc608370234aad6c2
https://doi.org/10.1002/chin.201621048
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Continuous and precise particle separation by electroosmotic flow control in microfluidic devices
Autor: Masahiro Yasuda, Masumi Yamada, Takahiro Kawamata, Minoru Seki
Publikováno v: ELECTROPHORESIS. 29:1423-1430
A new scheme has been described for continuous particle separation using EOF in microfluidic devices. We have previously reported a method for particle separation, called "pinched flow fractionation (PFF)", in which size-dependent and continuous part
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71787728be8c340620fdc5fe16258629
https://doi.org/10.1002/elps.200700658
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NTT's R&D: A platform for multimedia
Autor: Takahiro Kawamata
Publikováno v: Telecommunications Policy. 21:143-163
This paper describes cooperative research and development (R&D) activities in the I&CT (information and communications technology) industry in Japan historically, and also brings out the features of NTT's R&D capital as a national asset and its techn
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bd202d4ce87ee364cfc9ef74de89b922
https://doi.org/10.1016/s0308-5961(96)00075-4
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