Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Takahiro Isono"'
Autor:
Takahiro Isono, Takehiro Matsumoto, Masafumi Suzaki, Shigehisa Kubota, Susumu Kageyama, Akihiro Kawauchi, Atuyuki Wada
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Fibrosis is an important pathological mechanism in heart failure (HF) and is associated with poor prognosis. We analyzed fibrosis in HF patients using transcriptomic data. Genes differentially expressed between normal control and congestive
Externí odkaz:
https://doaj.org/article/b3d0005093cc4d99b61e9b89adad46a3
Autor:
Shigehisa Kubota, Tetsuya Yoshida, Susumu Kageyama, Takahiro Isono, Takeshi Yuasa, Junji Yonese, Ryoji Kushima, Akihiro Kawauchi, Tokuhiro Chano
Publikováno v:
World Journal of Surgical Oncology, Vol 18, Iss 1, Pp 1-11 (2020)
Abstract Background Accurate prediction of the prognosis of RCC using a single biomarker is challenging due to the genetic heterogeneity of the disease. However, it is essential to develop an accurate system to allow better patient selection for opti
Externí odkaz:
https://doaj.org/article/2604439c6f0f4a88bcf6c2d73aff6600
Autor:
Tsukuru Amano, Tokuhiro Chano, Takahiro Isono, Fuminori Kimura, Ryoji Kushima, Takashi Murakami
Publikováno v:
World Journal of Surgical Oncology, Vol 17, Iss 1, Pp 1-7 (2019)
Abstract Background Endometrioid ovarian carcinoma and clear cell ovarian carcinoma are both classified as endometriosis-associated ovarian cancers (EAOCs). Despite the high rates of recurrence and mortality of EAOC, only a few prognostic biomarkers
Externí odkaz:
https://doaj.org/article/181791a49462459a9f84ae77c0860df2
Autor:
Takahiro Isono, Masafumi Suzaki
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225721 (2019)
Starvation-resistant renal cell carcinoma (RCC) cell lines are considered dormant-state cells that survive even under glucose starvation. The cellular biological and global transcriptional analysis using these cells identified potential markers of ch
Externí odkaz:
https://doaj.org/article/091499ac981c49edac496ae813e75fec
Autor:
Ryo Fujiwara, Susumu Kageyama, Keiji Tomita, Eiki Hanada, Teruhiko Tsuru, Tetsuya Yoshida, Mitsuhiro Narita, Takahiro Isono, Akihiro Kawauchi
Publikováno v:
Case Reports in Oncology, Vol 8, Iss 2, Pp 339-344 (2015)
A 68-year-old man presented with gross hematuria. A papillary urethral tumor adjacent to the verumontanum was found by cystourethroscopy. Serum prostate-specific antigen (PSA) was 3.246 ng/ml. A transurethral biopsy specimen was most suggestive of a
Externí odkaz:
https://doaj.org/article/e1d9e399dc8a48b79d7990118362496d
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96168 (2014)
Some cancer cells can survive under glucose deprivation within the microenvironment of a tumor. Recently, we reported that N-linked (β-N-acetylglucosamine)2 [N-GlcNAc2]-modified proteins induce G2/M arrest and cell death under glucose deprivation. H
Externí odkaz:
https://doaj.org/article/633d01c21ae44c55b751c9a4724636fb
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60397 (2013)
Increased levels of N-linked (β-N- acetylglucosamine)2 [N-GlcNAc2]-modified proteins have been recognized to be an effective response to glucose deprivation. In the first step of this study, using a next generation sequencer, we investigated the glo
Externí odkaz:
https://doaj.org/article/6e005975e0484845aa28d86312dd7a55
Publikováno v:
PLoS ONE, Vol 8, Iss 11 (2013)
Externí odkaz:
https://doaj.org/article/8dbbab549ba94e78a66c061c0ebc718c
Autor:
Aiko Amagai, Harry MacWilliams, Takahiro Isono, Mariko Omatsu-Kanbe, Shinya Urano, Kazuo Yamamoto, Yasuo Maeda
Publikováno v:
International Journal of Cell Biology, Vol 2012 (2012)
We have previously demonstrated that a novel protein ZYG1 induces sexual cell fusion (zygote formation) of Dictyostelium cells. In the process of cell fusion, involvements of signal transduction pathways via Ca2+ and PKC (protein kinase C) have been
Externí odkaz:
https://doaj.org/article/012b0a6f63b34bac86d7e0ca9aeb2871
Autor:
Takahiro Isono
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18959 (2011)
Modification of serine and threonine residues in proteins by O-linked β-N-acetylglucosamine (O-GlcNAc) glycosylation is a feature of many cellular responses to the nutritional state and to stress. O-GlcNAc modification is reversibly regulated by O-l
Externí odkaz:
https://doaj.org/article/8886ecad018a40e3bfef2037e618c5af